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Items: 1 to 20 of 67

1.

Lyn tyrosine kinase is essential for erythropoietin-induced differentiation of J2E erythroid cells.

Tilbrook PA, Ingley E, Williams JH, Hibbs ML, Klinken SP.

EMBO J. 1997 Apr 1;16(7):1610-9.

2.

Disrupted signaling in a mutant J2E cell line that shows enhanced viability, but does not proliferate or differentiate, with erythropoietin.

Tilbrook PA, Bittorf T, Busfield SJ, Chappell D, Klinken SP.

J Biol Chem. 1996 Feb 16;271(7):3453-9.

3.

HS1 interacts with Lyn and is critical for erythropoietin-induced differentiation of erythroid cells.

Ingley E, Sarna MK, Beaumont JG, Tilbrook PA, Tsai S, Takemoto Y, Williams JH, Klinken SP.

J Biol Chem. 2000 Mar 17;275(11):7887-93.

4.

Maturation of erythroid cells and erythroleukemia development are affected by the kinase activity of Lyn.

Tilbrook PA, Palmer GA, Bittorf T, McCarthy DJ, Wright MJ, Sarna MK, Linnekin D, Cull VS, Williams JH, Ingley E, Schneider-Mergener J, Krystal G, Klinken SP.

Cancer Res. 2001 Mar 15;61(6):2453-8.

5.

Erythropoietin-stimulated Raf-1 tyrosine phosphorylation is associated with the tyrosine kinase Lyn in J2E erythroleukemic cells.

Tilbrook PA, Colley SM, McCarthy DJ, Marais R, Klinken SP.

Arch Biochem Biophys. 2001 Dec 1;396(1):128-32.

PMID:
11716471
6.
7.

Thyroid hormone receptor-interacting protein 1 modulates cytokine and nuclear hormone signaling in erythroid cells.

Ingley E, Chappell D, Poon SY, Sarna MK, Beaumont JG, Williams JH, Stillitano JP, Tsai S, Leedman PJ, Tilbrook PA, Klinken SP.

J Biol Chem. 2001 Nov 16;276(46):43428-34. Epub 2001 Sep 5.

8.

Amiloride suppresses erythropoietin-induced proliferation and MAP kinase, but potentiates differentiation of J2E cells.

Callus B, Tilbrook PA, Busfield SJ, Cull VS, Bittorf T, Klinken SP.

Exp Cell Res. 1995 Jul;219(1):39-46.

PMID:
7543055
10.

CD45 tyrosine phosphatase inhibits erythroid differentiation of umbilical cord blood CD34+ cells associated with selective inactivation of Lyn.

Harashima A, Suzuki M, Okochi A, Yamamoto M, Matsuo Y, Motoda R, Yoshioka T, Orita K.

Blood. 2002 Dec 15;100(13):4440-5. Epub 2002 Aug 8.

11.

Ectopic expression of transcription factor NF-E2 alters the phenotype of erythroid and monoblastoid cells.

Sayer MS, Tilbrook PA, Spadaccini A, Ingley E, Sarna MK, Williams JH, Andrews NC, Klinken SP.

J Biol Chem. 2000 Aug 18;275(33):25292-8.

12.

Retrovirally-produced erythropoietin effectively induces differentiation and proliferation of J2E erythroid cells.

Busfield SJ, Riches KJ, Sainsbury AJ, Rossi E, Garcia-Webb P, Klinken SP.

Growth Factors. 1993;9(2):87-97.

PMID:
8217220
13.

Role of a truncated erythropoietin receptor for erythroid differentiation.

Nakamura Y, Tokumoto Y, Nakauchi H.

Biochem Biophys Res Commun. 1996 Jan 5;218(1):205-9.

PMID:
8573132
14.

Lyn kinase plays important roles in erythroid expansion, maturation and erythropoietin receptor signalling by regulating inhibitory signalling pathways that control survival.

Slavova-Azmanova NS, Kucera N, Louw A, Satiaputra J, Handoko A, Singer P, Stone L, McCarthy DJ, Klinken SP, Hibbs ML, Ingley E.

Biochem J. 2014 May 1;459(3):455-66. doi: 10.1042/BJ20130903.

PMID:
24552351
15.

Erythropoietin exerts transcriptional and translational control over globin synthesis in J2E cells.

Busfield SJ, Chappell DS, Jennings G, Trengove NJ, Riches KJ, Callus BA, Tilbrook PA, Klinken SP.

Cell Growth Differ. 1995 Apr;6(4):429-37.

16.

Clonal analysis of erythropoietin stimulated J2E cells reveals asynchrony during terminal differentiation.

Busfield SJ, Farr TJ, Singh T, Sainsbury AJ, Klinken SP.

Growth Factors. 1993;9(4):307-15.

PMID:
8148159
17.

Enforced expression of HOX11 is associated with an immature phenotype in J2E erythroid cells.

Greene WK, Ford J, Dixon D, Tilbrook PA, Watt PM, Klinken SP, Kees UR.

Br J Haematol. 2002 Sep;118(3):909-17.

PMID:
12181065
19.
20.

Prevention of apoptosis in J2E erythroid cells by erythropoietin: involvement of JAK2 but not MAP kinases.

Chappell D, Tilbrook PA, Bittorf T, Colley SM, Meyer GT, Klinken SP.

Cell Death Differ. 1997 Feb;4(2):105-13.

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