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Kinase suppressor of Ras is ceramide-activated protein kinase.

Zhang Y, Yao B, Delikat S, Bayoumy S, Lin XH, Basu S, McGinley M, Chan-Hui PY, Lichenstein H, Kolesnick R.

Cell. 1997 Apr 4;89(1):63-72.


Kinase suppressor of Ras signals through Thr269 of c-Raf-1.

Xing HR, Kolesnick R.

J Biol Chem. 2001 Mar 30;276(13):9733-41. Epub 2000 Dec 27. Retraction in: J Biol Chem. 2013 Nov 22;288(47):34053.


Murine Ksr interacts with MEK and inhibits Ras-induced transformation.

Denouel-Galy A, Douville EM, Warne PH, Papin C, Laugier D, Calothy G, Downward J, Eychène A.

Curr Biol. 1998 Jan 1;8(1):46-55.


The protein kinase KSR interacts with 14-3-3 protein and Raf.

Xing H, Kornfeld K, Muslin AJ.

Curr Biol. 1997 May 1;7(5):294-300.


Phosphorylation of the kinase suppressor of ras by associated kinases.

Volle DJ, Fulton JA, Chaika OV, McDermott K, Huang H, Steinke LA, Lewis RE.

Biochemistry. 1999 Apr 20;38(16):5130-7.


Regulation of Raf-1 kinase by TNF via its second messenger ceramide and cross-talk with mitogenic signalling.

Müller G, Storz P, Bourteele S, Döppler H, Pfizenmaier K, Mischak H, Philipp A, Kaiser C, Kolch W.

EMBO J. 1998 Feb 2;17(3):732-42.


Kinase suppressor of Ras forms a multiprotein signaling complex and modulates MEK localization.

Stewart S, Sundaram M, Zhang Y, Lee J, Han M, Guan KL.

Mol Cell Biol. 1999 Aug;19(8):5523-34.


Phosphorylation of Raf by ceramide-activated protein kinase.

Yao B, Zhang Y, Delikat S, Mathias S, Basu S, Kolesnick R.

Nature. 1995 Nov 16;378(6554):307-10.


KSR stimulates Raf-1 activity in a kinase-independent manner.

Michaud NR, Therrien M, Cacace A, Edsall LC, Spiegel S, Rubin GM, Morrison DK.

Proc Natl Acad Sci U S A. 1997 Nov 25;94(24):12792-6. Erratum in: Proc Natl Acad Sci U S A 1998 mAR 3;95(5):2714-5.


Epidermal growth factor treatment enhances the kinase activity of kinase suppressor of Ras.

Xing HR, Lozano J, Kolesnick R.

J Biol Chem. 2000 Jun 9;275(23):17276-80.


Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase.

Yoder JH, Chong H, Guan KL, Han M.

EMBO J. 2004 Jan 14;23(1):111-9. Epub 2003 Dec 11.


KSR, a novel protein kinase required for RAS signal transduction.

Therrien M, Chang HC, Solomon NM, Karim FD, Wassarman DA, Rubin GM.

Cell. 1995 Dec 15;83(6):879-88.


C. elegans ksr-1 and ksr-2 have both unique and redundant functions and are required for MPK-1 ERK phosphorylation.

Ohmachi M, Rocheleau CE, Church D, Lambie E, Schedl T, Sundaram MV.

Curr Biol. 2002 Mar 5;12(5):427-33.


BAD enables ceramide to signal apoptosis via Ras and Raf-1.

Basu S, Bayoumy S, Zhang Y, Lozano J, Kolesnick R.

J Biol Chem. 1998 Nov 13;273(46):30419-26.


C-TAK1 regulates Ras signaling by phosphorylating the MAPK scaffold, KSR1.

Müller J, Ory S, Copeland T, Piwnica-Worms H, Morrison DK.

Mol Cell. 2001 Nov;8(5):983-93.

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