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Items: 1 to 20 of 110

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Mcl-1 in transgenic mice promotes survival in a spectrum of hematopoietic cell types and immortalization in the myeloid lineage.

Zhou P, Qian L, Bieszczad CK, Noelle R, Binder M, Levy NB, Craig RW.

Blood. 1998 Nov 1;92(9):3226-39.

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Mcl-1, a member of the Bcl-2 family, delays apoptosis induced by c-Myc overexpression in Chinese hamster ovary cells.

Reynolds JE, Yang T, Qian L, Jenkinson JD, Zhou P, Eastman A, Craig RW.

Cancer Res. 1994 Dec 15;54(24):6348-52.

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Mcl-1 regulates survival and sensitivity to diverse apoptotic stimuli in human non-small cell lung cancer cells.

Song L, Coppola D, Livingston S, Cress D, Haura EB.

Cancer Biol Ther. 2005 Mar;4(3):267-76. Epub 2005 Mar 20.

PMID:
15753661
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Vascular endothelial growth factor inhibits apoptotic death in hematopoietic cells after exposure to chemotherapeutic drugs by inducing MCL1 acting as an antiapoptotic factor.

Katoh O, Takahashi T, Oguri T, Kuramoto K, Mihara K, Kobayashi M, Hirata S, Watanabe H.

Cancer Res. 1998 Dec 1;58(23):5565-9.

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Exon skipping in Mcl-1 results in a bcl-2 homology domain 3 only gene product that promotes cell death.

Bingle CD, Craig RW, Swales BM, Singleton V, Zhou P, Whyte MK.

J Biol Chem. 2000 Jul 21;275(29):22136-46.

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Protection from cell death by mcl-1 is mediated by membrane hyperpolarization induced by K(+) channel activation.

Wang L, Zhou P, Craig RW, Lu L.

J Membr Biol. 1999 Nov 15;172(2):113-20.

PMID:
10556359
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EAT/mcl-1, a member of the bcl-2 related genes, confers resistance to apoptosis induced by cis-diammine dichloroplatinum (II) via a p53-independent pathway.

Ando T, Umezawa A, Suzuki A, Okita H, Sano M, Hiraoka Y, Aiso S, Saruta T, Hata J.

Jpn J Cancer Res. 1998 Dec;89(12):1326-33.

PMID:
10081494
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Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.

Opferman JT, Iwasaki H, Ong CC, Suh H, Mizuno S, Akashi K, Korsmeyer SJ.

Science. 2005 Feb 18;307(5712):1101-4.

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Elevated Mcl-1 perturbs lymphopoiesis, promotes transformation of hematopoietic stem/progenitor cells, and enhances drug resistance.

Campbell KJ, Bath ML, Turner ML, Vandenberg CJ, Bouillet P, Metcalf D, Scott CL, Cory S.

Blood. 2010 Oct 28;116(17):3197-207. doi: 10.1182/blood-2010-04-281071. Epub 2010 Jul 14.

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Influence of bcl-2 on cell death during the cultivation of a Chinese hamster ovary cell line expressing a chimeric antibody.

Tey BT, Singh RP, Piredda L, Piacentini M, Al-Rubeai M.

Biotechnol Bioeng. 2000 Apr 5;68(1):31-43.

PMID:
10699869
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Prolactin regulation of Bcl-2 family members: increased expression of bcl-xL but not mcl-1 or bad in Nb2-T cells.

Kochendoerfer SK, Krishnan N, Buckley DJ, Buckley AR.

J Endocrinol. 2003 Aug;178(2):265-73.

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Triggering of apoptosis by Puma is determined by the threshold set by prosurvival Bcl-2 family proteins.

Callus BA, Moujallad DM, Silke J, Gerl R, Jabbour AM, Ekert PG, Vaux DL.

J Mol Biol. 2008 Dec 12;384(2):313-23. doi: 10.1016/j.jmb.2008.09.041. Epub 2008 Sep 25.

PMID:
18835564
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Bim and Mcl-1 exert key roles in regulating JAK2V617F cell survival.

Rubert J, Qian Z, Andraos R, Guthy DA, Radimerski T.

BMC Cancer. 2011 Jan 19;11:24. doi: 10.1186/1471-2407-11-24.

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