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The highly conserved skb1 gene encodes a protein that interacts with Shk1, a fission yeast Ste20/PAK homolog.

Gilbreth M, Yang P, Wang D, Frost J, Polverino A, Cobb MH, Marcus S.

Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):13802-7.


Negative regulation of mitosis in fission yeast by the shk1 interacting protein skb1 and its human homolog, Skb1Hs.

Gilbreth M, Yang P, Bartholomeusz G, Pimental RA, Kansra S, Gadiraju R, Marcus S.

Proc Natl Acad Sci U S A. 1998 Dec 8;95(25):14781-6.


Direct activation of the fission yeast PAK Shk1 by the novel SH3 domain protein, Skb5.

Yang P, Pimental R, Lai H, Marcus S.

J Biol Chem. 1999 Dec 17;274(51):36052-7.


Cloning and characterization of shk2, a gene encoding a novel p21-activated protein kinase from fission yeast.

Yang P, Kansra S, Pimental RA, Gilbreth M, Marcus S.

J Biol Chem. 1998 Jul 17;273(29):18481-9.


Direct binding and In vivo regulation of the fission yeast p21-activated kinase shk1 by the SH3 domain protein scd2.

Chang E, Bartholomeusz G, Pimental R, Chen J, Lai H, Wang Lh, Yang P, Marcus S.

Mol Cell Biol. 1999 Dec;19(12):8066-74.


Activation of mitogen-activated protein kinase cascades by p21-activated protein kinases in cell-free extracts of Xenopus oocytes.

Polverino A, Frost J, Yang P, Hutchison M, Neiman AM, Cobb MH, Marcus S.

J Biol Chem. 1995 Nov 3;270(44):26067-70.


The kelch repeat protein, Tea1, is a potential substrate target of the p21-activated kinase, Shk1, in the fission yeast, Schizosaccharomyces pombe.

Kim H, Yang P, Catanuto P, Verde F, Lai H, Du H, Chang F, Marcus S.

J Biol Chem. 2003 Aug 8;278(32):30074-82. Epub 2003 May 22.


The highly conserved protein methyltransferase, Skb1, is a mediator of hyperosmotic stress response in the fission yeast Schizosaccharomyces pombe.

Bao S, Qyang Y, Yang P, Kim H, Du H, Bartholomeusz G, Henkel J, Pimental R, Verde F, Marcus S.

J Biol Chem. 2001 May 4;276(18):14549-52. Epub 2001 Mar 9.


Multiple regulatory domains on the Byr2 protein kinase.

Tu H, Barr M, Dong DL, Wigler M.

Mol Cell Biol. 1997 Oct;17(10):5876-87.


Fission yeast pak1+ encodes a protein kinase that interacts with Cdc42p and is involved in the control of cell polarity and mating.

Ottilie S, Miller PJ, Johnson DI, Creasy CL, Sells MA, Bagrodia S, Forsburg SL, Chernoff J.

EMBO J. 1995 Dec 1;14(23):5908-19.


Interaction of the somatostatin receptor subtype 1 with the human homolog of the Shk1 kinase-binding protein from yeast.

Schwärzler A, Kreienkamp HJ, Richter D.

J Biol Chem. 2000 Mar 31;275(13):9557-62.


Characterization of Pak2p, a pleckstrin homology domain-containing, p21-activated protein kinase from fission yeast.

Sells MA, Barratt JT, Caviston J, Ottilie S, Leberer E, Chernoff J.

J Biol Chem. 1998 Jul 17;273(29):18490-8.


The human homologue of the yeast proteins Skb1 and Hsl7p interacts with Jak kinases and contains protein methyltransferase activity.

Pollack BP, Kotenko SV, He W, Izotova LS, Barnoski BL, Pestka S.

J Biol Chem. 1999 Oct 29;274(44):31531-42.


Genetic and molecular characterization of Skb15, a highly conserved inhibitor of the fission yeast PAK, Shk1.

Kim HW, Yang P, Qyang Y, Lai H, Du H, Henkel JS, Kumar K, Bao S, Liu M, Marcus S.

Mol Cell. 2001 May;7(5):1095-101.


Human Ste20 homologue hPAK1 links GTPases to the JNK MAP kinase pathway.

Brown JL, Stowers L, Baer M, Trejo J, Coughlin S, Chant J.

Curr Biol. 1996 May 1;6(5):598-605.


Pch1(+), a second essential C-type cyclin gene in Schizosaccharomyces pombe.

Furnari BA, Russell P, Leatherwood J.

J Biol Chem. 1997 May 2;272(18):12100-6.

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