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Items: 1 to 20 of 201

1.

The tumour-suppressor gene patched encodes a candidate receptor for Sonic hedgehog.

Stone DM, Hynes M, Armanini M, Swanson TA, Gu Q, Johnson RL, Scott MP, Pennica D, Goddard A, Phillips H, Noll M, Hooper JE, de Sauvage F, Rosenthal A.

Nature. 1996 Nov 14;384(6605):129-34.

PMID:
8906787
2.

Sonic hedgehog signaling by the patched-smoothened receptor complex.

Murone M, Rosenthal A, de Sauvage FJ.

Curr Biol. 1999 Jan 28;9(2):76-84.

3.

Regional distribution of Sonic Hedgehog, patched, and smoothened mRNA in the adult rat brain.

Traiffort E, Charytoniuk DA, Faure H, Ruat M.

J Neurochem. 1998 Mar;70(3):1327-30.

4.

Effects of oncogenic mutations in Smoothened and Patched can be reversed by cyclopamine.

Taipale J, Chen JK, Cooper MK, Wang B, Mann RK, Milenkovic L, Scott MP, Beachy PA.

Nature. 2000 Aug 31;406(6799):1005-9.

PMID:
10984056
5.

Spatial regulation of a zebrafish patched homologue reflects the roles of sonic hedgehog and protein kinase A in neural tube and somite patterning.

Concordet JP, Lewis KE, Moore JW, Goodrich LV, Johnson RL, Scott MP, Ingham PW.

Development. 1996 Sep;122(9):2835-46.

6.

Characterization of two patched receptors for the vertebrate hedgehog protein family.

Carpenter D, Stone DM, Brush J, Ryan A, Armanini M, Frantz G, Rosenthal A, de Sauvage FJ.

Proc Natl Acad Sci U S A. 1998 Nov 10;95(23):13630-4.

7.

Expression of sonic hedgehog signal transducers, patched and smoothened, in human basal cell carcinoma.

Tojo M, Mori T, Kiyosawa H, Honma Y, Tanno Y, Kanazawa KY, Yokoya S, Kaneko F, Wanaka A.

Pathol Int. 1999 Aug;49(8):687-94.

PMID:
10504535
8.

Conservation of the hedgehog/patched signaling pathway from flies to mice: induction of a mouse patched gene by Hedgehog.

Goodrich LV, Johnson RL, Milenkovic L, McMahon JA, Scott MP.

Genes Dev. 1996 Feb 1;10(3):301-12.

9.

Human homolog of patched, a candidate gene for the basal cell nevus syndrome.

Johnson RL, Rothman AL, Xie J, Goodrich LV, Bare JW, Bonifas JM, Quinn AG, Myers RM, Cox DR, Epstein EH Jr, Scott MP.

Science. 1996 Jun 14;272(5268):1668-71.

PMID:
8658145
10.

Patching up Hedgehog.

Nusse R.

Nature. 1996 Nov 14;384(6605):119-20. No abstract available.

PMID:
8906783
11.

Patched acts catalytically to suppress the activity of Smoothened.

Taipale J, Cooper MK, Maiti T, Beachy PA.

Nature. 2002 Aug 22;418(6900):892-7. Erratum in: Nature 2002 Nov 28;420(6914):445.

PMID:
12192414
12.

The Shh signalling pathway in early tooth development.

Hardcastle Z, Hui CC, Sharpe PT.

Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):567-78.

PMID:
10512189
13.

Sonic Hedgehog signalling in the developing and adult brain.

Charytoniuk D, Porcel B, Rodríguez Gomez J, Faure H, Ruat M, Traiffort E.

J Physiol Paris. 2002 Jan-Mar;96(1-2):9-16.

PMID:
11755778
14.

Biochemical evidence that patched is the Hedgehog receptor.

Marigo V, Davey RA, Zuo Y, Cunningham JM, Tabin CJ.

Nature. 1996 Nov 14;384(6605):176-9.

PMID:
8906794
15.

Activating Smoothened mutations in sporadic basal-cell carcinoma.

Xie J, Murone M, Luoh SM, Ryan A, Gu Q, Zhang C, Bonifas JM, Lam CW, Hynes M, Goddard A, Rosenthal A, Epstein EH Jr, de Sauvage FJ.

Nature. 1998 Jan 1;391(6662):90-2.

PMID:
9422511
16.

Vertebrate Hedgehog signalling modulated by induction of a Hedgehog-binding protein.

Chuang PT, McMahon AP.

Nature. 1999 Feb 18;397(6720):617-21.

PMID:
10050855
17.

Cloning of a mouse smoothened cDNA and expression patterns of hedgehog signalling molecules during chondrogenesis and cartilage differentiation in clonal mouse EC cells, ATDC5.

Akiyama H, Shigeno C, Hiraki Y, Shukunami C, Kohno H, Akagi M, Konishi J, Nakamura T.

Biochem Biophys Res Commun. 1997 Jun 9;235(1):142-7.

PMID:
9196051
18.

Analysis of PTCH/SMO/SHH pathway genes in medulloblastoma.

Zurawel RH, Allen C, Chiappa S, Cato W, Biegel J, Cogen P, de Sauvage F, Raffel C.

Genes Chromosomes Cancer. 2000 Jan;27(1):44-51.

PMID:
10564585
19.

Conservation in hedgehog signaling: induction of a chicken patched homolog by Sonic hedgehog in the developing limb.

Marigo V, Scott MP, Johnson RL, Goodrich LV, Tabin CJ.

Development. 1996 Apr;122(4):1225-33.

20.

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