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Items: 1 to 20 of 92

1.

Grap is a novel SH3-SH2-SH3 adaptor protein that couples tyrosine kinases to the Ras pathway.

Feng GS, Ouyang YB, Hu DP, Shi ZQ, Gentz R, Ni J.

J Biol Chem. 1996 May 24;271(21):12129-32.

2.

Molecular cloning and expression of human grap-2, a novel leukocyte-specific SH2- and SH3-containing adaptor-like protein that binds to gab-1.

Qiu M, Hua S, Agrawal M, Li G, Cai J, Chan E, Zhou H, Luo Y, Liu M.

Biochem Biophys Res Commun. 1998 Dec 18;253(2):443-7.

PMID:
9878555
3.

The SH2 and SH3 domains of mammalian Grb2 couple the EGF receptor to the Ras activator mSos1.

Rozakis-Adcock M, Fernley R, Wade J, Pawson T, Bowtell D.

Nature. 1993 May 6;363(6424):83-5.

PMID:
8479540
4.

The role of a lymphoid-restricted, Grb2-like SH3-SH2-SH3 protein in T cell receptor signaling.

TrĂ¼b T, Frantz JD, Miyazaki M, Band H, Shoelson SE.

J Biol Chem. 1997 Jan 10;272(2):894-902.

6.

The SH2 and SH3 domain-containing protein GRB2 links receptor tyrosine kinases to ras signaling.

Lowenstein EJ, Daly RJ, Batzer AG, Li W, Margolis B, Lammers R, Ullrich A, Skolnik EY, Bar-Sagi D, Schlessinger J.

Cell. 1992 Aug 7;70(3):431-42.

PMID:
1322798
7.

Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells.

Jackman JK, Motto DG, Sun Q, Tanemoto M, Turck CW, Peltz GA, Koretzky GA, Findell PR.

J Biol Chem. 1995 Mar 31;270(13):7029-32.

8.
9.

The Grb2 adaptor.

Chardin P, Cussac D, Maignan S, Ducruix A.

FEBS Lett. 1995 Aug 1;369(1):47-51.

10.

SH2 and SH3-containing adaptor proteins: redundant or independent mediators of intracellular signal transduction.

Birge RB, Knudsen BS, Besser D, Hanafusa H.

Genes Cells. 1996 Jul;1(7):595-613. Review.

11.

Guanine-nucleotide-releasing factor hSos1 binds to Grb2 and links receptor tyrosine kinases to Ras signalling.

Li N, Batzer A, Daly R, Yajnik V, Skolnik E, Chardin P, Bar-Sagi D, Margolis B, Schlessinger J.

Nature. 1993 May 6;363(6424):85-8.

PMID:
8479541
12.
13.

The C-terminal SH3 domain of the adapter protein Grb2 binds with high affinity to sequences in Gab1 and SLP-76 which lack the SH3-typical P-x-x-P core motif.

Lewitzky M, Kardinal C, Gehring NH, Schmidt EK, Konkol B, Eulitz M, Birchmeier W, Schaeper U, Feller SM.

Oncogene. 2001 Mar 1;20(9):1052-62.

14.

Disabled-2 (Dab2) is an SH3 domain-binding partner of Grb2.

Xu XX, Yi T, Tang B, Lambeth JD.

Oncogene. 1998 Mar 26;16(12):1561-9.

15.

SH2/SH3 adaptor proteins can link tyrosine kinases to a Ste20-related protein kinase, HPK1.

Anafi M, Kiefer F, Gish GD, Mbamalu G, Iscove NN, Pawson T.

J Biol Chem. 1997 Oct 31;272(44):27804-11.

16.

Dynamin II associates with Grb2 SH3 domain in Ras transformed NIH3T3 cells.

Yoon SY, Koh WS, Lee MK, Park YM, Han MY.

Biochem Biophys Res Commun. 1997 May 29;234(3):539-43.

PMID:
9175747
17.

Tyrosine kinase signalling pathways.

Pawson T.

Princess Takamatsu Symp. 1994;24:303-22. Review.

PMID:
8983084
18.

Crystal structures of the SH2 domain of Grb2: highlight on the binding of a new high-affinity inhibitor.

Nioche P, Liu WQ, Broutin I, Charbonnier F, Latreille MT, Vidal M, Roques B, Garbay C, Ducruix A.

J Mol Biol. 2002 Feb 1;315(5):1167-77.

PMID:
11827484
19.

Inhibitors of Ras signal transduction as antitumor agents.

Garbay C, Liu WQ, Vidal M, Roques BP.

Biochem Pharmacol. 2000 Oct 15;60(8):1165-9. Review.

PMID:
11007954
20.

Hyaluronan promotes CD44v3-Vav2 interaction with Grb2-p185(HER2) and induces Rac1 and Ras signaling during ovarian tumor cell migration and growth.

Bourguignon LY, Zhu H, Zhou B, Diedrich F, Singleton PA, Hung MC.

J Biol Chem. 2001 Dec 28;276(52):48679-92. Epub 2001 Oct 17.

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