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Items: 1 to 20 of 91

1.

Pennyroyal toxicity: measurement of toxic metabolite levels in two cases and review of the literature.

Anderson IB, Mullen WH, Meeker JE, Khojasteh-BakhtSC, Oishi S, Nelson SD, Blanc PD.

Ann Intern Med. 1996 Apr 15;124(8):726-34. Review.

PMID:
8633832
2.

Multiple organ failure after ingestion of pennyroyal oil from herbal tea in two infants.

Bakerink JA, Gospe SM Jr, Dimand RJ, Eldridge MW.

Pediatrics. 1996 Nov;98(5):944-7.

PMID:
8909490
3.

Menthofuran-dependent and independent aspects of pulegone hepatotoxicity: roles of glutathione.

Thomassen D, Slattery JT, Nelson SD.

J Pharmacol Exp Ther. 1990 May;253(2):567-72.

PMID:
2338648
4.

Metabolism of (R)-(+)-pulegone in F344 rats.

Chen LJ, Lebetkin EH, Burka LT.

Drug Metab Dispos. 2001 Dec;29(12):1567-77.

5.

The metabolism of the abortifacient terpene, (R)-(+)-pulegone, to a proximate toxin, menthofuran.

Gordon WP, Huitric AC, Seth CL, McClanahan RH, Nelson SD.

Drug Metab Dispos. 1987 Sep-Oct;15(5):589-94.

PMID:
2891472
6.
7.

Metabolism of (R)-(+)-pulegone and (R)-(+)-menthofuran by human liver cytochrome P-450s: evidence for formation of a furan epoxide.

Khojasteh-Bakht SC, Chen W, Koenigs LL, Peter RM, Nelson SD.

Drug Metab Dispos. 1999 May;27(5):574-80.

8.
10.

Metabolism of (R)-(+)-menthofuran in Fischer-344 rats: identification of sulfonic acid metabolites.

Chen LJ, Lebetkin EH, Burka LT.

Drug Metab Dispos. 2003 Oct;31(10):1208-13.

11.

Safety and nutritional assessment of GM plants and derived food and feed: the role of animal feeding trials.

EFSA GMO Panel Working Group on Animal Feeding Trials.

Food Chem Toxicol. 2008 Mar;46 Suppl 1:S2-70. doi: 10.1016/j.fct.2008.02.008. Epub 2008 Feb 13. Review.

PMID:
18328408
12.

Mitigation of pennyroyal oil hepatotoxicity in the mouse.

Sztajnkrycer MD, Otten EJ, Bond GR, Lindsell CJ, Goetz RJ.

Acad Emerg Med. 2003 Oct;10(10):1024-8.

13.

14C-labeled pulegone and metabolites binding to alpha2u-globulin in kidneys of male F-344 rats.

Ferguson LJ, Lebetkin EH, Lih FB, Tomer KB, Parkinson HD, Borghoff SJ, Burka LT.

J Toxicol Environ Health A. 2007 Sep;70(17):1416-23.

PMID:
17687727
14.

Biotransformations of R-(+)-pulegone and menthofuran in vitro: chemical basis for toxicity.

Madyastha KM, Raj CP.

Biochem Biophys Res Commun. 1990 Dec 31;173(3):1086-92.

PMID:
2268314
17.

Quantitative determination of pulegone in pennyroyal oil by FT-IR spectroscopy.

Petrakis EA, Kimbaris AC, Pappas CS, Tarantilis PA, Polissiou MG.

J Agric Food Chem. 2009 Nov 11;57(21):10044-8. doi: 10.1021/jf9026052.

PMID:
19817373
18.

A decades-long investigation of acute metabolism-based hepatotoxicity by herbal constituents: a case study of pennyroyal oil.

Gordon P, Khojasteh SC.

Drug Metab Rev. 2015 Feb;47(1):12-20. doi: 10.3109/03602532.2014.990032. Epub 2014 Dec 16. Review.

PMID:
25512112
19.

Glutathione S-transferase catalyzes the isomerization of (R)-2-hydroxymenthofuran to mintlactones.

Khojasteh-Bakht SC, Nelson SD, Atkins WM.

Arch Biochem Biophys. 1999 Oct 1;370(1):59-65.

PMID:
10496977
20.

Biotransformation of 1,8-cineole in the brushtail possum (Trichosurus vulpecula).

Boyle R, McLean S, Davies NW.

Xenobiotica. 2000 Sep;30(9):915-32.

PMID:
11055269

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