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Items: 1 to 20 of 226

1.
3.

Maintenance of quaternary structure in the frozen state stabilizes lactate dehydrogenase during freeze-drying.

Anchordoquy TJ, Izutsu KI, Randolph TW, Carpenter JF.

Arch Biochem Biophys. 2001 Jun 1;390(1):35-41.

PMID:
11368512
4.

Polymers protect lactate dehydrogenase during freeze-drying by inhibiting dissociation in the frozen state.

Anchordoquy TJ, Carpenter JF.

Arch Biochem Biophys. 1996 Aug 15;332(2):231-8.

PMID:
8806730
5.
6.

Hydrogen bonding between sugar and protein is responsible for inhibition of dehydration-induced protein unfolding.

Allison SD, Chang B, Randolph TW, Carpenter JF.

Arch Biochem Biophys. 1999 May 15;365(2):289-98.

PMID:
10328824
7.

State transitions and physicochemical aspects of cryoprotection and stabilization in freeze-drying of Lactobacillus rhamnosus GG (LGG).

Pehkonen KS, Roos YH, Miao S, Ross RP, Stanton C.

J Appl Microbiol. 2008 Jun;104(6):1732-43. doi: 10.1111/j.1365-2672.2007.03719.x. Epub 2008 Jan 31.

8.

Interactions of stabilizing additives with proteins during freeze-thawing and freeze-drying.

Carpenter JF, Arakawa T, Crowe JH.

Dev Biol Stand. 1992;74:225-38; discussion 238-9. Review.

PMID:
1592173
9.

Rapid optimization of protein freeze-drying formulations using ultra scale-down and factorial design of experiment in microplates.

Grant Y, Matejtschuk P, Dalby PA.

Biotechnol Bioeng. 2009 Dec 1;104(5):957-64. doi: 10.1002/bit.22448.

PMID:
19530082
10.

Protein formulation and lyophilization cycle design: prevention of damage due to freeze-concentration induced phase separation.

Heller MC, Carpenter JF, Randolph TW.

Biotechnol Bioeng. 1999 Apr 20;63(2):166-74.

PMID:
10099593
11.

Trehalose and hyaluronic acid coordinately stabilized freeze-dried pancreatic kininogenase.

Zhang Y, Ji B, Ling P, Zhang T.

Eur J Pharm Biopharm. 2007 Jan;65(1):18-25. Epub 2006 Jul 15.

PMID:
16950608
12.

The effect of co-spray drying with polyethylene glycol 4000 on the crystallinity and physical form of lactose.

Chidavaenzi OC, Buckton G, Koosha F.

Int J Pharm. 2001 Mar 23;216(1-2):43-9.

PMID:
11274805
13.

Distinct effects of sucrose and trehalose on protein stability during supercritical fluid drying and freeze-drying.

Jovanović N, Bouchard A, Hofland GW, Witkamp GJ, Crommelin DJ, Jiskoot W.

Eur J Pharm Sci. 2006 Mar;27(4):336-45. Epub 2005 Dec 9.

PMID:
16338123
14.

Effect of mannitol crystallinity on the stabilization of enzymes during freeze-drying.

Izutsu K, Yoshioka S, Terao T.

Chem Pharm Bull (Tokyo). 1994 Jan;42(1):5-8.

PMID:
8124765
15.
16.

Excipient crystallinity and its protein-structure-stabilizing effect during freeze-drying.

Izutsu K, Kojima S.

J Pharm Pharmacol. 2002 Aug;54(8):1033-9.

PMID:
12195816
17.

The effect of mannitol crystallization in mannitol-sucrose systems on LDH stability during freeze-drying.

Al-Hussein A, Gieseler H.

J Pharm Sci. 2012 Jul;101(7):2534-44. doi: 10.1002/jps.23173. Epub 2012 Apr 25.

PMID:
22535541
18.

Stabilization of phosphofructokinase during air-drying with sugars and sugar/transition metal mixtures.

Carpenter JF, Martin B, Crowe LM, Crowe JH.

Cryobiology. 1987 Oct;24(5):455-64.

PMID:
2958239
19.

Protein stability during freezing: separation of stresses and mechanisms of protein stabilization.

Bhatnagar BS, Bogner RH, Pikal MJ.

Pharm Dev Technol. 2007;12(5):505-23. Review.

PMID:
17963151
20.

Physical characterisation of formulations for the development of two stable freeze-dried proteins during both dried and liquid storage.

Passot S, Fonseca F, Alarcon-Lorca M, Rolland D, Marin M.

Eur J Pharm Biopharm. 2005 Aug;60(3):335-48.

PMID:
15894475

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