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Items: 1 to 20 of 114

1.

Werner syndrome and biological ageing: a molecular genetic hypothesis.

Thweatt R, Goldstein S.

Bioessays. 1993 Jun;15(6):421-6. Review.

PMID:
8357345
2.

Studies on the molecular-genetic basis of replicative senescence in Werner syndrome and normal fibroblasts.

Goldstein S, Murano S, Benes H, Moerman EJ, Jones RA, Thweatt R, Shmookler Reis RJ, Howard BH.

Exp Gerontol. 1989;24(5-6):461-8.

PMID:
2632280
3.
4.

Identification of gene sequences overexpressed in senescent and Werner syndrome human fibroblasts.

Lecka-Czernik B, Moerman EJ, Jones RA, Goldstein S.

Exp Gerontol. 1996 Jan-Apr;31(1-2):159-74.

PMID:
8706786
5.

Werner syndrome: a molecular genetic hypothesis.

Goldstein S, Murano S, Shmookler Reis RJ.

J Gerontol. 1990 Jan;45(1):B3-8. Review.

PMID:
2404059
6.

Investigation of the signaling pathways involved in the proliferative life span barriers in werner syndrome fibroblasts.

Davis T, Faragher RG, Jones CJ, Kipling D.

Ann N Y Acad Sci. 2004 Jun;1019:274-7.

PMID:
15247028
7.

Diverse gene sequences are overexpressed in werner syndrome fibroblasts undergoing premature replicative senescence.

Murano S, Thweatt R, Shmookler Reis RJ, Jones RA, Moerman EJ, Goldstein S.

Mol Cell Biol. 1991 Aug;11(8):3905-14.

8.
9.

Telomere-based proliferative lifespan barriers in Werner-syndrome fibroblasts involve both p53-dependent and p53-independent mechanisms.

Davis T, Singhrao SK, Wyllie FS, Haughton MF, Smith PJ, Wiltshire M, Wynford-Thomas D, Jones CJ, Faragher RG, Kipling D.

J Cell Sci. 2003 Apr 1;116(Pt 7):1349-57.

11.

Normal telomere erosion rates at the single cell level in Werner syndrome fibroblast cells.

Baird DM, Davis T, Rowson J, Jones CJ, Kipling D.

Hum Mol Genet. 2004 Jul 15;13(14):1515-24. Epub 2004 May 18.

PMID:
15150162
12.

No increase in senescence-associated beta-galactosidase activity in Werner syndrome fibroblasts after exposure to H2O2.

de Magalhães JP, Migeot V, Mainfroid V, de Longueville F, Remacle J, Toussaint O.

Ann N Y Acad Sci. 2004 Jun;1019:375-8. Review.

PMID:
15247048
13.
14.

Gene expression profiling in Werner syndrome closely resembles that of normal aging.

Kyng KJ, May A, Kølvraa S, Bohr VA.

Proc Natl Acad Sci U S A. 2003 Oct 14;100(21):12259-64. Epub 2003 Oct 3.

15.

DNA repair fine structure in Werner's syndrome cell lines.

Webb DK, Evans MK, Bohr VA.

Exp Cell Res. 1996 May 1;224(2):272-8.

PMID:
8612704
16.

Accelerated loss of telomeric repeats may not explain accelerated replicative decline of Werner syndrome cells.

Schulz VP, Zakian VA, Ogburn CE, McKay J, Jarzebowicz AA, Edland SD, Martin GM.

Hum Genet. 1996 Jun;97(6):750-4.

PMID:
8641691
17.

Analysis of microsatellite instability and hypermutation of immunoglobulin variable genes in Werner syndrome.

Rosner K, Winter DB, Skovgaard GL, Oshima J, Gearhart PJ, Bohr VA.

Mech Ageing Dev. 2001 Aug;122(11):1121-33.

PMID:
11389928
18.

Can we say that senescent cells cause ageing?

Bird J, Ostler EL, Faragher RG.

Exp Gerontol. 2003 Nov-Dec;38(11-12):1319-26. Review.

PMID:
14698811
19.

Gene expression responses to DNA damage are altered in human aging and in Werner Syndrome.

Kyng KJ, May A, Stevnsner T, Becker KG, Kølvrå S, Bohr VA.

Oncogene. 2005 Jul 28;24(32):5026-42.

PMID:
15897889
20.

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