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Items: 1 to 20 of 98

1.

Synthesis and structure-activity relationships of new dimeric mitomycin derivatives; 7-N,7'-N'-bis(omega-thioalkyl)dimitomycins.

Kono M, Saitoh Y, Kasai M, Shirahata K, Morimoto M, Ashizawa T.

J Antibiot (Tokyo). 1993 Sep;46(9):1428-38.

2.

New potent mitomycin derivatives: synthesis and antitumor activity of 7,7-(ethylenedioxy)mitomycins.

Kanda Y, Arai H, Ashizawa T, Morimoto M, Kasai M.

J Med Chem. 1992 Jul 24;35(15):2781-6.

PMID:
1495011
3.

Synthesis and antitumor activity of novel mitomycin derivatives containing functional groups at the C-6-methyl position.

Arai H, Kanda Y, Ashizawa T, Morimoto M, Gomi K, Kono M, Kasai M.

J Med Chem. 1994 Jun 10;37(12):1794-804.

PMID:
8021918
4.

Synthesis and antitumor activity of a novel water soluble mitomycin analog; 7-N-[2-[[2-(gamma-L-glutamylamino)ethyl]dithio]ethyl]mitomycin C.

Kono M, Saitoh Y, Kasai M, Sato A, Shirahata K, Morimoto M, Ashizawa T.

Chem Pharm Bull (Tokyo). 1989 Apr;37(4):1128-30.

PMID:
2766417
5.

Synthesis and antitumor activity of various 6-demethylmitomycins and 6-demethyl-6-halomitomycins.

Arai H, Ashizawa T, Gomi K, Kono M, Saito H, Kasai M.

J Med Chem. 1995 Aug 4;38(16):3025-33.

PMID:
7636865
6.

Synthesis and biological evaluation of quinocarcin derivatives: thioalkyl-substituted quinones and hydroquinones.

Saito H, Hirata T, Kasai M, Fujimoto K, Ashizawa T, Morimoto M, Sato A.

J Med Chem. 1991 Jul;34(7):1959-66.

PMID:
2066968
7.

New sugar mitomycin C analogues: preparation, murine P388 antitumor activity, and leukopenia induction.

Talebian A, Green D, Hammer CF, McPherson E, Schein PS.

J Pharm Sci. 1990 Dec;79(12):1105-8.

PMID:
2127804
8.

Synthesis and antineoplastic activity of CNC-cysteamine and related compounds.

Tang WC, Schmid J, Fiebig HH, Eisenbrand G.

J Cancer Res Clin Oncol. 1986;111(1):25-30.

PMID:
3949847
9.

Mitomycin derivatives having unique condensed-ring structures. Their synthesis and antitumor activity.

Arai H, Kanda Y, Ashizawa T, Morimoto M, Gomi K, Kono M, Kasai M.

J Antibiot (Tokyo). 1994 Nov;47(11):1312-21.

10.

6H-pyrazolo[4,5,1-de]acridin-6-ones as a novel class of antitumor agents. Synthesis and biological activity.

Sugaya T, Mimura Y, Shida Y, Osawa Y, Matsukuma I, Ikeda S, Akinaga S, Morimoto M, Ashizawa T, Okabe M, et al.

J Med Chem. 1994 Apr 1;37(7):1028-32.

PMID:
8151613
11.

Synthesis and antineoplastic activity of mitosene analogues of the mitomycins.

Hodges JC, Remers WA, Bradner WT.

J Med Chem. 1981 Oct;24(10):1184-91.

PMID:
7328580
12.

Antitumor activity of 7-N-phenyl derivatives of mitomycin C in the leukemia P388 system.

Imai R, Ashizawa T, Urakawa C, Morimoto M, Nakamura N.

Gan. 1980 Aug;71(4):560-2.

PMID:
7437130
13.

Characteristics of the antitumor activity of M-16 and M-18, major metabolites of a new mitomycin C derivative KW-2149, in mice.

Ashizawa T, Okamoto A, Okabe M, Kobayashi S, Arai H, Saito H, Kasai M, Gomi K.

Anticancer Drugs. 1995 Dec;6(6):763-70.

PMID:
8845489
14.

Antitumor activity and toxicity in animals of N-7[2-(4-nitrophenyldithio) ethyl] mitomycin C (BMY-25067).

Bradner WT, Rose WC, Schurig JE, Florczyk AP.

Invest New Drugs. 1990;8 Suppl 1:S1-7.

PMID:
2380013
15.
16.

Antitumor activity of 7-N-[[2-[[2-(gamma-L-glutamylamino)ethyl]dithio]ethyl]]-mitomycin C.

Morimoto M, Ashizawa T, Ohno H, Azuma M, Kobayashi E, Okabe M, Gomi K, Kono M, Saitoh Y, Kanda Y, et al.

Cancer Res. 1991 Jan 1;51(1):110-5.

17.

Synthesis, cell growth inhibition, and antitumor screening of 2-(p-n-butylanilino)purines and their nucleoside analogues.

Wright GE, Dudycz LW, Kazimierczuk Z, Brown NC, Khan NN.

J Med Chem. 1987 Jan;30(1):109-16.

PMID:
3806587
18.

Antineoplastic activity of azacarbazoles. I. Synthesis and antitumor properties of alpha-carboline and its selected derivatives.

Wieczorek J, PeczyƄska-Czoch W, Mordarski M, Kaczmarek L, Nantka-Namirski P.

Arch Immunol Ther Exp (Warsz). 1986;34(3):315-21.

PMID:
3592935
19.

Synthesis and antitumor activity of novel 6-alkyl-6-demethylmitomycins.

Arai H, Kanda Y, Ashizawa T, Morimoto M, Gomi K, Kono M, Kasai M.

J Med Chem. 1994 Jun 10;37(12):1805-9.

PMID:
8021919
20.

Synthesis and antitumor activities of novel benzoylphenylurea derivatives.

Okada H, Koyanagi T, Yamada N, Haga T.

Chem Pharm Bull (Tokyo). 1991 Sep;39(9):2308-15.

PMID:
1804543

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