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Items: 1 to 20 of 67

1.

A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).

Vlahos CJ, Matter WF, Hui KY, Brown RF.

J Biol Chem. 1994 Feb 18;269(7):5241-8.

PMID:
8106507
2.

The inhibition of phosphatidylinositol 3-kinase by quercetin and analogs.

Matter WF, Brown RF, Vlahos CJ.

Biochem Biophys Res Commun. 1992 Jul 31;186(2):624-31.

PMID:
1323287
3.

Inhibition of MG-63 cell proliferation and PDGF-stimulated cellular processes by inhibitors of phosphatidylinositol 3-kinase.

Thomas JE, Venugopalan M, Galvin R, Wang Y, Bokoch GM, Vlahos CJ.

J Cell Biochem. 1997 Feb;64(2):182-95.

PMID:
9027579
4.
5.

Antagonists of phosphatidylinositol 3-kinase block activation of several novel protein kinases in neutrophils.

Ding J, Vlahos CJ, Liu R, Brown RF, Badwey JA.

J Biol Chem. 1995 May 12;270(19):11684-91.

7.

Biochemical and pharmacological studies with KT7692 and LY294002 on the role of phosphatidylinositol 3-kinase in Fc epsilon RI-mediated signal transduction.

Yano H, Agatsuma T, Nakanishi S, Saitoh Y, Fukui Y, Nonomura Y, Matsuda Y.

Biochem J. 1995 Nov 15;312 ( Pt 1):145-50.

8.

Characterization of a soluble adrenal phosphatidylinositol 4-kinase reveals wortmannin sensitivity of type III phosphatidylinositol kinases.

Downing GJ, Kim S, Nakanishi S, Catt KJ, Balla T.

Biochemistry. 1996 Mar 19;35(11):3587-94.

PMID:
8639510
9.

The phosphatidylinositol 3-kinase inhibitors wortmannin and LY294002 inhibit autophagy in isolated rat hepatocytes.

Blommaart EF, Krause U, Schellens JP, Vreeling-Sindelárová H, Meijer AJ.

Eur J Biochem. 1997 Jan 15;243(1-2):240-6.

10.

Investigation of neutrophil signal transduction using a specific inhibitor of phosphatidylinositol 3-kinase.

Vlahos CJ, Matter WF, Brown RF, Traynor-Kaplan AE, Heyworth PG, Prossnitz ER, Ye RD, Marder P, Schelm JA, Rothfuss KJ, et al.

J Immunol. 1995 Mar 1;154(5):2413-22.

PMID:
7868907
15.

Phosphatidylinositol 3-kinase activity is required for early endosome fusion.

Jones AT, Clague MJ.

Biochem J. 1995 Oct 1;311 ( Pt 1):31-4.

16.
18.

Potent inhibitors of phosphatidylinositol 3 (PI3) kinase that have antiproliferative activity only when delivered as prodrug forms.

O'Brien NJ, Amran S, Medan J, Cleary B, Deady LW, Jennings IG, Thompson PE, Abbott BM.

ChemMedChem. 2013 Jun;8(6):914-8. doi: 10.1002/cmdc.201200583. Epub 2013 Apr 8.

PMID:
23568455
19.

Structural determinants of phosphoinositide 3-kinase inhibition by wortmannin, LY294002, quercetin, myricetin, and staurosporine.

Walker EH, Pacold ME, Perisic O, Stephens L, Hawkins PT, Wymann MP, Williams RL.

Mol Cell. 2000 Oct;6(4):909-19.

20.

Possible involvement of phosphatidylinositol 3-kinase in regulated exocytosis: studies in chromaffin cells with inhibitor LY294002.

Chasserot-Golaz S, Hubert P, Thiersé D, Dirrig S, Vlahos CJ, Aunis D, Bader MF.

J Neurochem. 1998 Jun;70(6):2347-56.

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