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Items: 1 to 20 of 128

1.

Pharmacokinetics and pharmacodynamics of dichloroacetate in children with lactic acidosis due to severe malaria.

Krishna S, Agbenyega T, Angus BJ, Bedu-Addo G, Ofori-Amanfo G, Henderson G, Szwandt IS, O'Brien R, Stacpoole PW.

QJM. 1995 May;88(5):341-9.

PMID:
7796089
2.

Population kinetics, efficacy, and safety of dichloroacetate for lactic acidosis due to severe malaria in children.

Agbenyega T, Planche T, Bedu-Addo G, Ansong D, Owusu-Ofori A, Bhattaram VA, Nagaraja NV, Shroads AL, Henderson GN, Hutson AD, Derendorf H, Krishna S, Stacpoole PW.

J Clin Pharmacol. 2003 Apr;43(4):386-96.

PMID:
12723459
3.

The disposition and effects of two doses of dichloroacetate in adults with severe falciparum malaria.

Krishna S, Supanaranond W, Pukrittayakamee S, Kuile FT, Ruprah M, White NJ.

Br J Clin Pharmacol. 1996 Jan;41(1):29-34.

4.

Amelioration of lactic acidosis with dichloroacetate during liver transplantation in humans.

Shangraw RE, Winter R, Hromco J, Robinson ST, Gallaher EJ.

Anesthesiology. 1994 Nov;81(5):1127-38.

PMID:
7978471
5.

Dichloroacetate for lactic acidosis in severe malaria: a pharmacokinetic and pharmacodynamic assessment.

Krishna S, Supanaranond W, Pukrittayakamee S, Karter D, Supputamongkol Y, Davis TM, Holloway PA, White NJ.

Metabolism. 1994 Aug;43(8):974-81.

PMID:
8052155
6.

Plasmodium berghei infection: dichloroacetate improves survival in rats with lactic acidosis.

Holloway PA, Knox K, Bajaj N, Chapman D, White NJ, O'Brien R, Stacpoole PW, Krishna S.

Exp Parasitol. 1995 Jun;80(4):624-32.

PMID:
7758543
7.

Controlled clinical trial of dichloroacetate for treatment of congenital lactic acidosis in children.

Stacpoole PW, Kerr DS, Barnes C, Bunch ST, Carney PR, Fennell EM, Felitsyn NM, Gilmore RL, Greer M, Henderson GN, Hutson AD, Neiberger RE, O'Brien RG, Perkins LA, Quisling RG, Shroads AL, Shuster JJ, Silverstein JH, Theriaque DW, Valenstein E.

Pediatrics. 2006 May;117(5):1519-31.

PMID:
16651305
8.
9.

Efficacy of dichloroacetate as a lactate-lowering drug.

Stacpoole PW, Nagaraja NV, Hutson AD.

J Clin Pharmacol. 2003 Jul;43(7):683-91. Review.

PMID:
12856382
10.

[Dose dependent effects of dichloroacetate on lactic acidosis in dogs].

Fujita Y, Fukui A, Yoshida H, Ohsumi A, Sakai T, Takaori M.

Masui. 1989 Aug;38(8):1005-11. Japanese.

PMID:
2810694
11.

A controlled clinical trial of dichloroacetate for treatment of lactic acidosis in adults. The Dichloroacetate-Lactic Acidosis Study Group.

Stacpoole PW, Wright EC, Baumgartner TG, Bersin RM, Buchalter S, Curry SH, Duncan CA, Harman EM, Henderson GN, Jenkinson S, et al.

N Engl J Med. 1992 Nov 26;327(22):1564-9.

12.

Effect of dichloroacetate in the treatment of anoxic lactic acidosis in dogs.

Sheikh A, Fleisher G, Delgado Paredes C, Caputo G, Schaible D, Egler J, Swedlow D.

Crit Care Med. 1986 Nov;14(11):970-3.

PMID:
3021391
13.

Dichloroacetate stabilizes the intraoperative acid-base balance during liver transplantation.

Shangraw RE, Lohan-Mannion D, Hayes A, Moriarty RM, Fu R, Robinson ST.

Liver Transpl. 2008 Jul;14(7):989-98. doi: 10.1002/lt.21485.

14.

Effects of dichloroacetate following canine asphyxial arrest.

Gin-Shaw SL, Barsan WG, Eymer V, Hedges J.

Ann Emerg Med. 1988 May;17(5):473-7.

PMID:
3129970
15.

Effects of various doses of sodium dichloroacetate on hyperlactatemia in fed ischemic rats.

Dimlich RV, Kaplan J, Timerding BL, Van Ligten PF.

Ann Emerg Med. 1989 Nov;18(11):1162-71. Review.

PMID:
2683899
16.

Pharmacokinetics of dichloroacetate in adult patients with lactic acidosis.

Henderson GN, Curry SH, Derendorf H, Wright EC, Stacpoole PW.

J Clin Pharmacol. 1997 May;37(5):416-25.

PMID:
9156374
17.

Congenital lactic acidosis.

Kuroda Y, Naito E, Takeda E, Yokota I, Miyao M.

Enzyme. 1987;38(1-4):108-14.

PMID:
3440441
18.

Treatment of severe lactic acidosis with dichloroacetate.

Blackshear PJ, Fang LS, Axelrod L.

Diabetes Care. 1982 Jul-Aug;5(4):391-4.

PMID:
7151655
19.

Depletion of lactate by dichloroacetate reduces cardiac efficiency after hemorrhagic shock.

Barbee RW, Kline JA, Watts JA.

Shock. 2000 Aug;14(2):208-14.

PMID:
10947168
20.

Mechanism of dichloroacetate-induced hypolactatemia in humans with or without cirrhosis.

Shangraw RE, Jahoor F.

Metabolism. 2004 Aug;53(8):1087-94.

PMID:
15281024

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