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Items: 1 to 20 of 374

1.

Phenoxyl radicals of etoposide (VP-16) can directly oxidize intracellular thiols: protective versus damaging effects of phenolic antioxidants.

Tyurina YY, Tyurin VA, Yalowich JC, Quinn PJ, Claycamp HG, Schor NF, Pitt BR, Kagan VE.

Toxicol Appl Pharmacol. 1995 Apr;131(2):277-88.

PMID:
7716769
2.

Ascorbate is the primary reductant of the phenoxyl radical of etoposide in the presence of thiols both in cell homogenates and in model systems.

Kagan VE, Yalowich JC, Day BW, Goldman R, Gantchev TG, Stoyanovsky DA.

Biochemistry. 1994 Aug 16;33(32):9651-60.

PMID:
8068642
3.
5.
6.

Mechanism-based chemopreventive strategies against etoposide-induced acute myeloid leukemia: free radical/antioxidant approach.

Kagan VE, Yalowich JC, Borisenko GG, Tyurina YY, Tyurin VA, Thampatty P, Fabisiak JP.

Mol Pharmacol. 1999 Sep;56(3):494-506.

7.

Pro-oxidant and antioxidant mechanisms of etoposide in HL-60 cells: role of myeloperoxidase.

Kagan VE, Kuzmenko AI, Tyurina YY, Shvedova AA, Matsura T, Yalowich JC.

Cancer Res. 2001 Nov 1;61(21):7777-84.

8.

Recycling and redox cycling of phenolic antioxidants.

Kagan VE, Tyurina YY.

Ann N Y Acad Sci. 1998 Nov 20;854:425-34. Review.

PMID:
9928449
9.

Anti-/pro-oxidant effects of phenolic compounds in cells: are colchicine metabolites chain-breaking antioxidants?

Modriansky M, Tyurina YY, Tyurin VA, Matsura T, Shvedova AA, Yalowich JC, Kagan VE.

Toxicology. 2002 Aug 1;177(1):105-17.

PMID:
12126799
10.

Phenoxyl radical-induced thiol-dependent generation of reactive oxygen species: implications for benzene toxicity.

Stoyanovsky DA, Goldman R, Claycamp HG, Kagan VE.

Arch Biochem Biophys. 1995 Mar 10;317(2):315-23.

PMID:
7893144
11.

Direct evidence for recycling of myeloperoxidase-catalyzed phenoxyl radicals of a vitamin E homologue, 2,2,5,7,8-pentamethyl-6-hydroxy chromane, by ascorbate/dihydrolipoate in living HL-60 cells.

Kagan VE, Kuzmenko AI, Shvedova AA, Kisin ER, Li R, Martin I, Quinn PJ, Tyurin VA, Tyurina YY, Yalowich JC.

Biochim Biophys Acta. 2003 Mar 17;1620(1-3):72-84.

PMID:
12595076
12.
13.

Inhibition of Na+/K(+)-ATPase by phenoxyl radicals of etoposide (VP-16): role of sulfhydryls oxidation.

Kurella EG, Osipov AN, Goldman R, Boldyrev AA, Kagan VE.

Biochim Biophys Acta. 1995 Nov 21;1232(1-2):52-8.

14.

Reversible thiol-dependent activation of ryanodine-sensitive Ca2+ release channel by etoposide (VP-16) phenoxyl radical.

Fabisiak JP, Ritov VB, Kagan VE.

Antioxid Redox Signal. 2000 Spring;2(1):73-82.

PMID:
11232603
15.

Myeloperoxidase-catalyzed phenoxyl radicals of vitamin E homologue, 2,2,5,7,8-pentamethyl- 6-hydroxychromane, do not induce oxidative stress in live HL-60 cells.

Kagan VE, Kuzmenko AI, Shvedova AA, Kisin ER, Tyurina YY, Yalowich JC.

Biochem Biophys Res Commun. 2000 Apr 21;270(3):1086-92.

PMID:
10772954
16.

Endogenous ascorbate regenerates vitamin E in the retina directly and in combination with exogenous dihydrolipoic acid.

Stoyanovsky DA, Goldman R, Darrow RM, Organisciak DT, Kagan VE.

Curr Eye Res. 1995 Mar;14(3):181-9.

PMID:
7796601
17.

Phenol-induced in vivo oxidative stress in skin: evidence for enhanced free radical generation, thiol oxidation, and antioxidant depletion.

Murray AR, Kisin E, Castranova V, Kommineni C, Gunther MR, Shvedova AA.

Chem Res Toxicol. 2007 Dec;20(12):1769-77. Epub 2007 Oct 9.

PMID:
17922553
18.

Interactions of the antitumor drug, etoposide, with reduced thiols in vitro and in vivo.

Katki AG, Kalyanaraman B, Sinha BK.

Chem Biol Interact. 1987;62(3):237-47.

PMID:
3040275
19.

Generation and recycling of radicals from phenolic antioxidants.

Kagan VE, Serbinova EA, Packer L.

Arch Biochem Biophys. 1990 Jul;280(1):33-9.

PMID:
2162153
20.

Antioxidant and pro-oxidant effect of the thiolic compounds N-acetyl-L-cysteine and glutathione against free radical-induced lipid peroxidation.

Sagristá ML, García AE, Africa De Madariaga M, Mora M.

Free Radic Res. 2002 Mar;36(3):329-40.

PMID:
12071352

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