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Items: 1 to 20 of 51

1.

Novel steroid 5 alpha-reductase inhibitor FK143: its dual inhibition against the two isozymes and its effect on transcription of the isozyme genes.

Kojo H, Nakayama O, Hirosumi J, Chida N, Notsu Y, Okuhara M.

Mol Pharmacol. 1995 Sep;48(3):401-6.

PMID:
7565619
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4-(1-benzoylindol-3-yl)butyric acids and FK143: novel nonsteroidal inhibitors of steroid 5 alpha-reductase (II).

Sawada K, Okada S, Golden P, Kayakiri N, Sawada Y, Hashimoto M, Tanaka H.

Chem Pharm Bull (Tokyo). 1999 Apr;47(4):481-91.

PMID:
10319427
5.

Actions of 5alpha-reductase inhibitors on the epididymis.

Robaire B, Henderson NA.

Mol Cell Endocrinol. 2006 May 16;250(1-2):190-5. Epub 2006 Feb 14. Review.

PMID:
16476520
6.

Preventive effect of FK143, a 5alpha-reductase inhibitor, on chemical hepatocarcinogenesis in rats.

Maruyama S, Nagasue N, Dhar DK, Yamanoi A, El-Assal ON, Satoh K, Okita K.

Clin Cancer Res. 2001 Jul;7(7):2096-104.

8.

Pharmacokinetics and pharmacodynamics of FK143, a nonsteroidal inhibitor of steroid 5 alpha-reductase, in healthy volunteers.

Katashima M, Irino T, Shimojo F, Kawamura A, Kageyama H, Higashi N, Miyao Y, Tokuma Y, Hata T, Yamamoto K, Sawada Y, Iga T.

Clin Pharmacol Ther. 1998 Mar;63(3):354-66.

PMID:
9542479
9.

Indole derivatives as a new class of steroid 5 alpha-reductase inhibitors.

Takami H, Koshimura H, Kishibayashi N, Ishii A, Nonaka H, Aoyama S, Kase H, Kumazawa T.

J Med Chem. 1996 Dec 20;39(26):5047-52.

PMID:
8978835
11.
12.

FK143, a novel nonsteroidal inhibitor of steroid 5 alpha-reductase: (1) In vitro effects on human and animal prostatic enzymes.

Hirosumi J, Nakayama O, Fagan T, Sawada K, Chida N, Inami M, Takahashi S, Kojo H, Notsu Y, Okuhara M.

J Steroid Biochem Mol Biol. 1995 Apr;52(4):357-63.

PMID:
7734404
13.

FK143, a novel nonsteroidal inhibitor of steroid 5 alpha-reductase: (2) In vivo effects on rat and dog prostates.

Hirosumi J, Nakayama O, Chida N, Inami M, Fagan T, Sawada K, Shigematsu S, Kojo H, Notsu Y, Okuhara M.

J Steroid Biochem Mol Biol. 1995 Apr;52(4):365-73.

PMID:
7734405
14.

Effects of a new non-steroidal 5 alpha-reductase inhibitor, FK143, on the prostate gland in beagle dogs.

Inami M, Kawamura I, Naoe Y, Tsujimoto S, Mizota T, Manda T, Shimomura K.

Jpn J Pharmacol. 1997 Jun;74(2):187-94.

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Cloning and differential expression of steroid 5 alpha-reductase type 1 (Srd5a1) and type 2 (Srd5a2) from the Harderian glands of hamsters.

Ramos L, Chávez B, Vilchis F.

Gen Comp Endocrinol. 2010 Apr 1;166(2):388-95. doi: 10.1016/j.ygcen.2009.12.010. Epub 2009 Dec 16.

PMID:
20018190
18.

Z-350, a novel compound with alpha 1-adrenoceptor antagonistic and steroid 5 alpha-reductase inhibitory actions: pharmacological properties in vivo.

Fukuta Y, Fukuda Y, Higashino R, Yoshida K, Ogishima M, Tamaki H, Takei M.

J Pharmacol Exp Ther. 1999 Sep;290(3):1013-8.

PMID:
10454472
19.

Characterization of Chinese hamster ovary cell lines expressing human steroid 5 alpha-reductase isozymes.

Thigpen AE, Cala KM, Russell DW.

J Biol Chem. 1993 Aug 15;268(23):17404-12.

20.

Selective non-steroidal inhibitors of 5 alpha-reductase type 1.

Occhiato EG, Guarna A, Danza G, Serio M.

J Steroid Biochem Mol Biol. 2004 Jan;88(1):1-16. Review.

PMID:
15026079

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