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Items: 1 to 20 of 94

1.

Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53.

Jones SN, Roe AE, Donehower LA, Bradley A.

Nature. 1995 Nov 9;378(6553):206-8.

PMID:
7477327
2.

Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53.

Montes de Oca Luna R, Wagner DS, Lozano G.

Nature. 1995 Nov 9;378(6553):203-6.

PMID:
7477326
3.

The tumorigenic potential and cell growth characteristics of p53-deficient cells are equivalent in the presence or absence of Mdm2.

Jones SN, Sands AT, Hancock AR, Vogel H, Donehower LA, Linke SP, Wahl GM, Bradley A.

Proc Natl Acad Sci U S A. 1996 Nov 26;93(24):14106-11.

4.

The loss of mdm2 induces p53-mediated apoptosis.

de Rozieres S, Maya R, Oren M, Lozano G.

Oncogene. 2000 Mar 23;19(13):1691-7.

5.

Rescue of embryonic lethality in Mdm4-null mice by loss of Trp53 suggests a nonoverlapping pathway with MDM2 to regulate p53.

Parant J, Chavez-Reyes A, Little NA, Yan W, Reinke V, Jochemsen AG, Lozano G.

Nat Genet. 2001 Sep;29(1):92-5.

PMID:
11528400
6.

MDM2 expression during mouse embryogenesis and the requirement of p53.

Léveillard T, Gorry P, Niederreither K, Wasylyk B.

Mech Dev. 1998 Jun;74(1-2):189-93.

7.

mdm2 deletion does not alter growth characteristics of p53-deficient embryo fibroblasts.

McMasters KM, Montes de Oca Luna R, Peña JR, Lozano G.

Oncogene. 1996 Oct 17;13(8):1731-6.

PMID:
8895519
8.

Mutation at p53 serine 389 does not rescue the embryonic lethality in mdm2 or mdm4 null mice.

Iwakuma T, Parant JM, Fasulo M, Zwart E, Jacks T, de Vries A, Lozano G.

Oncogene. 2004 Oct 7;23(46):7644-50.

PMID:
15361844
9.

Rescue of Mdm4-deficient mice by Mdm2 reveals functional overlap of Mdm2 and Mdm4 in development.

Steinman HA, Hoover KM, Keeler ML, Sands AT, Jones SN.

Oncogene. 2005 Nov 24;24(53):7935-40.

PMID:
16027727
10.

Switching mechanisms of cell death in mdm2- and mdm4-null mice by deletion of p53 downstream targets.

Chavez-Reyes A, Parant JM, Amelse LL, de Oca Luna RM, Korsmeyer SJ, Lozano G.

Cancer Res. 2003 Dec 15;63(24):8664-9.

11.

The mdm2 proto-oncogene.

Haines DS.

Leuk Lymphoma. 1997 Jul;26(3-4):227-38. Review.

PMID:
9322885
12.

Overexpression of Mdm2 in mice reveals a p53-independent role for Mdm2 in tumorigenesis.

Jones SN, Hancock AR, Vogel H, Donehower LA, Bradley A.

Proc Natl Acad Sci U S A. 1998 Dec 22;95(26):15608-12.

13.

Mdm2: keeping p53 under control.

Piette J, Neel H, Maréchal V.

Oncogene. 1997 Aug 28;15(9):1001-10. Review.

14.

Targeted expression of MDM2 uncouples S phase from mitosis and inhibits mammary gland development independent of p53.

Lundgren K, Montes de Oca Luna R, McNeill YB, Emerick EP, Spencer B, Barfield CR, Lozano G, Rosenberg MP, Finlay CA.

Genes Dev. 1997 Mar 15;11(6):714-25.

15.

The expression of MDM2 and other p53-regulated proteins in the tissues of the developing rat.

Ibrahim AP, Gallimore PH, Grand RJ.

Biochim Biophys Acta. 1997 Feb 28;1350(3):306-16.

PMID:
9061027
16.

Loss of one but not two mdm2 null alleles alters the tumour spectrum in p53 null mice.

McDonnell TJ, Montes de Oca Luna R, Cho S, Amelse LL, Chavez-Reyes A, Lozano G.

J Pathol. 1999 Jul;188(3):322-8.

PMID:
10419603
17.

MDM2 oncogene as a novel target for human cancer therapy.

Zhang, Wang H.

Curr Pharm Des. 2000 Mar;6(4):393-416. Review.

PMID:
10788589
18.

An alternative splice form of Mdm2 induces p53-independent cell growth and tumorigenesis.

Steinman HA, Burstein E, Lengner C, Gosselin J, Pihan G, Duckett CS, Jones SN.

J Biol Chem. 2004 Feb 6;279(6):4877-86.

19.

Deletion of p21 cannot substitute for p53 loss in rescue of mdm2 null lethality.

Montes de Oca Luna R, Amelse LL, Chavez-Reyes A, Evans SC, Brugarolas J, Jacks T, Lozano G.

Nat Genet. 1997 Aug;16(4):336-7. No abstract available.

PMID:
9241268
20.

MDM2--master regulator of the p53 tumor suppressor protein.

Momand J, Wu HH, Dasgupta G.

Gene. 2000 Jan 25;242(1-2):15-29. Review.

PMID:
10721693

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