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Items: 1 to 20 of 89

1.

Clonal gene therapy: transplanted mouse fibroblast clones express human alpha 1-antitrypsin gene in vivo.

Garver RI Jr, Chytil A, Courtney M, Crystal RG.

Science. 1987 Aug 14;237(4816):762-4.

PMID:
3497452
2.

Production of glycosylated physiologically "normal" human alpha 1-antitrypsin by mouse fibroblasts modified by insertion of a human alpha 1-antitrypsin cDNA using a retroviral vector.

Garver RI Jr, Chytil A, Karlsson S, Fells GA, Brantly ML, Courtney M, Kantoff PW, Nienhuis AW, Anderson WF, Crystal RG.

Proc Natl Acad Sci U S A. 1987 Feb;84(4):1050-4.

3.

Adenovirus-mediated transfer of a recombinant alpha 1-antitrypsin gene to the lung epithelium in vivo.

Rosenfeld MA, Siegfried W, Yoshimura K, Yoneyama K, Fukayama M, Stier LE, Pääkkö PK, Gilardi P, Stratford-Perricaudet LD, Perricaudet M, et al.

Science. 1991 Apr 19;252(5004):431-4.

PMID:
2017680
4.
5.

Alpha 1-antitrypsin deficiency caused by the alpha 1-antitrypsin Nullmattawa gene. An insertion mutation rendering the alpha 1-antitrypsin gene incapable of producing alpha 1-antitrypsin.

Curiel D, Brantly M, Curiel E, Stier L, Crystal RG.

J Clin Invest. 1989 Apr;83(4):1144-52. Erratum in: J Clin Invest 1989 Sep;84(3):following 1041.

7.

Adenovirus-mediated transfer of a recombinant human alpha 1-antitrypsin cDNA to human endothelial cells.

Lemarchand P, Jaffe HA, Danel C, Cid MC, Kleinman HK, Stratford-Perricaudet LD, Perricaudet M, Pavirani A, Lecocq JP, Crystal RG.

Proc Natl Acad Sci U S A. 1992 Jul 15;89(14):6482-6.

8.

Retroviral mediated transfer and expression of human alpha 1-antitrypsin in cultured cells.

Ledley FD, Grenett HE, Bartos DP, Woo SL.

Gene. 1987;61(1):113-8.

PMID:
3502102
9.

Intraperitoneal in vivo gene therapy to deliver alpha 1-antitrypsin to the systemic circulation.

Setoguchi Y, Jaffe HA, Chu CS, Crystal RG.

Am J Respir Cell Mol Biol. 1994 Apr;10(4):369-77.

PMID:
8136153
10.

The human alpha-1-antitrypsin gene is efficiently expressed from two tissue-specific promotors in transgenic mice.

Rüther U, Tripodi M, Cortese R, Wagner EF.

Nucleic Acids Res. 1987 Sep 25;15(18):7519-29.

11.
12.

Implantation of genetically manipulated fibroblasts into mice as antitumor alpha-interferon therapy.

Ogura H, Tani K, Ozawa K, Nagata S, Asano S, Takaku F.

Cancer Res. 1990 Aug 15;50(16):5102-6.

13.

Clonal gene therapy: in vivo expression of a transplanted monoclonal population of murine fibroblasts containing a retrovirus inserted human alpha 1-antitrypsin gene.

Garver RI Jr, Chytil A, Courtney M, Crystal RG.

Trans Assoc Am Physicians. 1987;100:10-20. No abstract available.

PMID:
2842911
14.

Human neutrophils express the alpha 1-antitrypsin gene and produce alpha 1-antitrypsin.

du Bois RM, Bernaudin JF, Paakko P, Hubbard R, Takahashi H, Ferrans V, Crystal RG.

Blood. 1991 Jun 15;77(12):2724-30.

15.

Characterization of a human alpha 1-antitrypsin null allele involving aberrant mRNA splicing.

Laubach VE, Ryan WJ, Brantly M.

Hum Mol Genet. 1993 Jul;2(7):1001-5.

PMID:
8364536
16.

Molecular characterisation of the defective alpha 1-antitrypsin alleles PI Mwurzburg (Pro369Ser), Mheerlen (Pro369Leu), and Q0lisbon (Thr68Ile).

Poller W, Merklein F, Schneider-Rasp S, Haack A, Fechner H, Wang H, Anagnostopoulos I, Weidinger S.

Eur J Hum Genet. 1999 Apr;7(3):321-31.

17.

Species- and tissue-specific expression of human alpha 1-antitrypsin in transgenic mice.

Kelsey GD, Povey S, Bygrave AE, Lovell-Badge RH.

Genes Dev. 1987 Apr;1(2):161-71.

18.

Hepatic gene therapy: efficient retroviral-mediated gene transfer into rat hepatocytes in vivo.

Kolodka TM, Finegold M, Kay MA, Woo SL.

Somat Cell Mol Genet. 1993 Sep;19(5):491-7. Erratum in: Somat Cell Mol Genet 1994 May;20(3):251.

PMID:
7980740
19.

[The effects on melanoma and immunological mechanism of human interferon-alpha gene therapy by fibroblasts].

Chen M, Lin Z, Cao X.

Zhonghua Zheng Xing Wai Ke Za Zhi. 2000 Sep;16(5):298-301. Chinese.

PMID:
11593666
20.

Evaluation of recombinant DNA-directed E.coli produced alpha 1-antitrypsin as an anti-neutrophil elastase for potential use as replacement therapy of alpha 1-antitrypsin deficiency.

Straus SD, Fells GA, Wewers MD, Courtney M, Tessier LH, Tolstoshev P, Lecocq JP, Crystal RG.

Biochem Biophys Res Commun. 1985 Aug 15;130(3):1177-84.

PMID:
3896239

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