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Results by year

Year	Number of Results
1999	1
2003	1
2007	2
2008	9
2009	15
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690 results

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Riluzole enhances the antitumor effects of temozolomide via suppression of MGMT expression in glioblastoma.

Yamada T, Tsuji S, Nakamura S, Egashira Y, Shimazawa M, Nakayama N, Yano H, Iwama T, Hara H. Yamada T, et al. J Neurosurg. 2020 Mar 13;134(3):701-710. doi: 10.3171/2019.12.JNS192682. J Neurosurg. 2020. PMID: 32168477

Pharmacological inhibition of serine synthesis enhances temozolomide efficacy by decreasing O⁶-methylguanine DNA methyltransferase (MGMT) expression and reactive oxygen species (ROS)-mediated DNA damage in glioblastoma.

Jin L, Kiang KM, Cheng SY, Leung GK. Jin L, et al. Lab Invest. 2022 Feb;102(2):194-203. doi: 10.1038/s41374-021-00666-7. Epub 2021 Oct 8. Lab Invest. 2022. PMID: 34625658 Free article.

Delineation of MGMT Hypermethylation as a Biomarker for Veliparib-Mediated Temozolomide-Sensitizing Therapy of Glioblastoma.

Gupta SK, Kizilbash SH, Carlson BL, Mladek AC, Boakye-Agyeman F, Bakken KK, Pokorny JL, Schroeder MA, Decker PA, Cen L, Eckel-Passow JE, Sarkar G, Ballman KV, Reid JM, Jenkins RB, Verhaak RG, Sulman EP, Kitange GJ, Sarkaria JN. Gupta SK, et al. J Natl Cancer Inst. 2015 Nov 27;108(5):djv369. doi: 10.1093/jnci/djv369. Print 2016 May. J Natl Cancer Inst. 2015. PMID: 26615020 Free PMC article.

Up-Regulation of Cyclooxygenase-2 (COX-2) Expression by Temozolomide (TMZ) in Human Glioblastoma (GBM) Cell Lines.

Lombardi F, Augello FR, Artone S, Gugu MK, Cifone MG, Cinque B, Palumbo P. Lombardi F, et al. Int J Mol Sci. 2022 Jan 28;23(3):1545. doi: 10.3390/ijms23031545. Int J Mol Sci. 2022. PMID: 35163465 Free PMC article.

Effect of lomeguatrib-temozolomide combination on MGMT promoter methylation and expression in primary glioblastoma tumor cells.

Taspinar M, Ilgaz S, Ozdemir M, Ozkan T, Oztuna D, Canpinar H, Rey JA, Sunguroğlu A, Castresana JS, Ugur HC. Taspinar M, et al. Tumour Biol. 2013 Jun;34(3):1935-47. doi: 10.1007/s13277-013-0738-7. Epub 2013 Mar 22. Tumour Biol. 2013. PMID: 23519841

NMDA receptor signaling induces the chemoresistance of temozolomide via upregulation of MGMT expression in glioblastoma cells.

Tsuji S, Nakamura S, Shoda K, Yamada T, Shimazawa M, Nakayama N, Iwama T, Hara H. Tsuji S, et al. J Neurooncol. 2022 Nov;160(2):375-388. doi: 10.1007/s11060-022-04154-w. Epub 2022 Oct 29. J Neurooncol. 2022. PMID: 36308592

Inhibition of GSH synthesis potentiates temozolomide-induced bystander effect in glioblastoma.

Kohsaka S, Takahashi K, Wang L, Tanino M, Kimura T, Nishihara H, Tanaka S. Kohsaka S, et al. Cancer Lett. 2013 Apr 30;331(1):68-75. doi: 10.1016/j.canlet.2012.12.005. Epub 2012 Dec 12. Cancer Lett. 2013. PMID: 23246370

Efficacy of protracted temozolomide dosing is limited in MGMT unmethylated GBM xenograft models.

Cen L, Carlson BL, Pokorny JL, Mladek AC, Grogan PT, Schroeder MA, Decker PA, Anderson SK, Giannini C, Wu W, Ballman KV, Kitange GJ, Sarkaria JN. Cen L, et al. Neuro Oncol. 2013 Jun;15(6):735-46. doi: 10.1093/neuonc/not010. Epub 2013 Mar 10. Neuro Oncol. 2013. PMID: 23479134 Free PMC article.

Evaluation of MGMT promoter methylation status and correlation with temozolomide response in orthotopic glioblastoma xenograft model.

Kitange GJ, Carlson BL, Mladek AC, Decker PA, Schroeder MA, Wu W, Grogan PT, Giannini C, Ballman KV, Buckner JC, James CD, Sarkaria JN. Kitange GJ, et al. J Neurooncol. 2009 Mar;92(1):23-31. doi: 10.1007/s11060-008-9737-8. Epub 2008 Nov 15. J Neurooncol. 2009. PMID: 19011762 Free PMC article.

Optimizing glioblastoma temozolomide chemotherapy employing lentiviral-based anti-MGMT shRNA technology.

Viel T, Monfared P, Schelhaas S, Fricke IB, Kuhlmann MT, Fraefel C, Jacobs AH. Viel T, et al. Mol Ther. 2013 Mar;21(3):570-9. doi: 10.1038/mt.2012.278. Epub 2013 Jan 15. Mol Ther. 2013. PMID: 23319055 Free PMC article.

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