Similar articles for PMID: 31899072

Year	Number of Results
1999	1
2003	1
2007	1
2008	3
2009	11
2010	11
2011	15
2012	11
2013	13
2014	14
2015	14
2016	16
2017	17
2018	24
2019	29
2020	42
2021	81
2022	38
2023	26
2024	0

1

Glucocerebrosidase Activity Modulates Neuronal Susceptibility to Pathological α-Synuclein Insult.

Henderson MX, Sedor S, McGeary I, Cornblath EJ, Peng C, Riddle DM, Li HL, Zhang B, Brown HJ, Olufemi MF, Bassett DS, Trojanowski JQ, Lee VMY. Henderson MX, et al. Neuron. 2020 Mar 4;105(5):822-836.e7. doi: 10.1016/j.neuron.2019.12.004. Epub 2019 Dec 30. Neuron. 2020. PMID: 31899072 Free PMC article.

2

A novel glucosylceramide synthase inhibitor attenuates alpha synuclein pathology and lysosomal dysfunction in preclinical models of synucleinopathy.

Cosden M, Jinn S, Yao L, Gretzula CA, Kandebo M, Toolan D, Hatcher NG, Ma L, Lemaire W, Adam GC, Burlein C, Minnick C, Flick R, Watt ML, Mulhearn J, Fraley M, Drolet RE, Marcus JN, Smith SM. Cosden M, et al. Neurobiol Dis. 2021 Nov;159:105507. doi: 10.1016/j.nbd.2021.105507. Epub 2021 Sep 9. Neurobiol Dis. 2021. PMID: 34509608 Free article.

3

Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons.

Mazzulli JR, Zunke F, Tsunemi T, Toker NJ, Jeon S, Burbulla LF, Patnaik S, Sidransky E, Marugan JJ, Sue CM, Krainc D. Mazzulli JR, et al. J Neurosci. 2016 Jul 20;36(29):7693-706. doi: 10.1523/JNEUROSCI.0628-16.2016. J Neurosci. 2016. PMID: 27445146 Free PMC article.

4

Neuronopathic GBA1L444P Mutation Accelerates Glucosylsphingosine Levels and Formation of Hippocampal Alpha-Synuclein Inclusions.

Mahoney-Crane CL, Viswanathan M, Russell D, Curtiss RAC, Freire J, Bobba SS, Coyle SD, Kandebo M, Yao L, Wan BL, Hatcher NG, Smith SM, Marcus JN, Volpicelli-Daley LA. Mahoney-Crane CL, et al. J Neurosci. 2023 Jan 18;43(3):501-521. doi: 10.1523/JNEUROSCI.0680-22.2022. Epub 2022 Dec 7. J Neurosci. 2023. PMID: 36639889 Free PMC article.

5

Augmenting CNS glucocerebrosidase activity as a therapeutic strategy for parkinsonism and other Gaucher-related synucleinopathies.

Sardi SP, Clarke J, Viel C, Chan M, Tamsett TJ, Treleaven CM, Bu J, Sweet L, Passini MA, Dodge JC, Yu WH, Sidman RL, Cheng SH, Shihabuddin LS. Sardi SP, et al. Proc Natl Acad Sci U S A. 2013 Feb 26;110(9):3537-42. doi: 10.1073/pnas.1220464110. Epub 2013 Jan 7. Proc Natl Acad Sci U S A. 2013. PMID: 23297226 Free PMC article.

6

Glucocerebrosidase gene therapy prevents α-synucleinopathy of midbrain dopamine neurons.

Rocha EM, Smith GA, Park E, Cao H, Brown E, Hayes MA, Beagan J, McLean JR, Izen SC, Perez-Torres E, Hallett PJ, Isacson O. Rocha EM, et al. Neurobiol Dis. 2015 Oct;82:495-503. doi: 10.1016/j.nbd.2015.09.009. Epub 2015 Sep 25. Neurobiol Dis. 2015. PMID: 26392287 Free article.

7

Acid ceramidase inhibition ameliorates α-synuclein accumulation upon loss of GBA1 function.

Kim MJ, Jeon S, Burbulla LF, Krainc D. Kim MJ, et al. Hum Mol Genet. 2018 Jun 1;27(11):1972-1988. doi: 10.1093/hmg/ddy105. Hum Mol Genet. 2018. PMID: 29579237 Free PMC article.

8

Sustained Systemic Glucocerebrosidase Inhibition Induces Brain α-Synuclein Aggregation, Microglia and Complement C1q Activation in Mice.

Rocha EM, Smith GA, Park E, Cao H, Graham AR, Brown E, McLean JR, Hayes MA, Beagan J, Izen SC, Perez-Torres E, Hallett PJ, Isacson O. Rocha EM, et al. Antioxid Redox Signal. 2015 Aug 20;23(6):550-64. doi: 10.1089/ars.2015.6307. Epub 2015 Jul 29. Antioxid Redox Signal. 2015. PMID: 26094487 Free PMC article.

9

GBA1 mutations: Prospects for exosomal biomarkers in α-synuclein pathologies.

Johnson PH, Weinreb NJ, Cloyd JC, Tuite PJ, Kartha RV. Johnson PH, et al. Mol Genet Metab. 2020 Feb;129(2):35-46. doi: 10.1016/j.ymgme.2019.10.006. Epub 2019 Oct 23. Mol Genet Metab. 2020. PMID: 31761523 Free PMC article. Review.

10

GBA1 Gene Mutations in α-Synucleinopathies-Molecular Mechanisms Underlying Pathology and Their Clinical Significance.

Granek Z, Barczuk J, Siwecka N, Rozpędek-Kamińska W, Kucharska E, Majsterek I. Granek Z, et al. Int J Mol Sci. 2023 Jan 20;24(3):2044. doi: 10.3390/ijms24032044. Int J Mol Sci. 2023. PMID: 36768367 Free PMC article. Review.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Results by year

Text availability

Article attribute

Article type

Publication date

327 results

Results by year