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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1996 2
1997 2
1998 2
2001 2
2003 2
2005 2
2006 1
2007 3
2008 1
2009 2
2010 5
2011 1
2012 5
2013 15
2014 16
2015 16
2016 13
2017 18
2018 12
2019 6
2020 12
2021 15
2022 14
2023 4
2024 0

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Similar articles for PMID: 31887252

145 results

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Page 1
The 1,2,4-Triazolo[4,3-a]pyrazin-3-one as a Versatile Scaffold for the Design of Potent Adenosine Human Receptor Antagonists. Structural Investigations to Target the A2A Receptor Subtype.
Falsini M, Squarcialupi L, Catarzi D, Varano F, Betti M, Dal Ben D, Marucci G, Buccioni M, Volpini R, De Vita T, Cavalli A, Colotta V. Falsini M, et al. J Med Chem. 2017 Jul 13;60(13):5772-5790. doi: 10.1021/acs.jmedchem.7b00457. Epub 2017 Jun 16. J Med Chem. 2017. PMID: 28590753
The role of 5-arylalkylamino- and 5-piperazino- moieties on the 7-aminopyrazolo[4,3-d]pyrimidine core in affecting adenosine A1 and A2A receptor affinity and selectivity profiles.
Squarcialupi L, Betti M, Catarzi D, Varano F, Falsini M, Ravani A, Pasquini S, Vincenzi F, Salmaso V, Sturlese M, Varani K, Moro S, Colotta V. Squarcialupi L, et al. J Enzyme Inhib Med Chem. 2017 Dec;32(1):248-263. doi: 10.1080/14756366.2016.1247060. J Enzyme Inhib Med Chem. 2017. PMID: 28114825 Free PMC article.
Characterization of the potent and highly selective A2A receptor antagonists preladenant and SCH 412348 [7-[2-[4-2,4-difluorophenyl]-1-piperazinyl]ethyl]-2-(2-furanyl)-7H-pyrazolo[4,3-e][1,2,4]triazolo[1,5-c]pyrimidin-5-amine] in rodent models of movement disorders and depression.
Hodgson RA, Bertorelli R, Varty GB, Lachowicz JE, Forlani A, Fredduzzi S, Cohen-Williams ME, Higgins GA, Impagnatiello F, Nicolussi E, Parra LE, Foster C, Zhai Y, Neustadt BR, Stamford AW, Parker EM, Reggiani A, Hunter JC. Hodgson RA, et al. J Pharmacol Exp Ther. 2009 Jul;330(1):294-303. doi: 10.1124/jpet.108.149617. Epub 2009 Mar 30. J Pharmacol Exp Ther. 2009. PMID: 19332567
145 results