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Items: 1 to 20 of 108


Ultrasound-Induced Blood-Brain-Barrier Opening Enhances Anticancer Efficacy in the Treatment of Glioblastoma: Current Status and Future Prospects.

Deng Z, Sheng Z, Yan F.

J Oncol. 2019 Nov 3;2019:2345203. doi: 10.1155/2019/2345203. eCollection 2019. Review.


Focused ultrasound-induced blood-brain barrier opening to enhance temozolomide delivery for glioblastoma treatment: a preclinical study.

Wei KC, Chu PC, Wang HY, Huang CY, Chen PY, Tsai HC, Lu YJ, Lee PY, Tseng IC, Feng LY, Hsu PW, Yen TC, Liu HL.

PLoS One. 2013;8(3):e58995. doi: 10.1371/journal.pone.0058995. Epub 2013 Mar 19.


Focused ultrasound-mediated noninvasive blood-brain barrier modulation: preclinical examination of efficacy and safety in various sonication parameters.

Shin J, Kong C, Cho JS, Lee J, Koh CS, Yoon MS, Na YC, Chang WS, Chang JW.

Neurosurg Focus. 2018 Feb;44(2):E15. doi: 10.3171/2017.11.FOCUS17627.


Pharmacodynamic and therapeutic investigation of focused ultrasound-induced blood-brain barrier opening for enhanced temozolomide delivery in glioma treatment.

Liu HL, Huang CY, Chen JY, Wang HY, Chen PY, Wei KC.

PLoS One. 2014 Dec 9;9(12):e114311. doi: 10.1371/journal.pone.0114311. eCollection 2014.


Concurrent blood-brain barrier opening and local drug delivery using drug-carrying microbubbles and focused ultrasound for brain glioma treatment.

Ting CY, Fan CH, Liu HL, Huang CY, Hsieh HY, Yen TC, Wei KC, Yeh CK.

Biomaterials. 2012 Jan;33(2):704-12. doi: 10.1016/j.biomaterials.2011.09.096. Epub 2011 Oct 22.


Focused ultrasound-induced blood-brain barrier opening to enhance interleukin-12 delivery for brain tumor immunotherapy: a preclinical feasibility study.

Chen PY, Hsieh HY, Huang CY, Lin CY, Wei KC, Liu HL.

J Transl Med. 2015;13:93. doi: 10.1186/s12967-015-0451-y. Epub 2015 Mar 17.


Enhanced delivery of paclitaxel liposomes using focused ultrasound with microbubbles for treating nude mice bearing intracranial glioblastoma xenografts.

Shen Y, Pi Z, Yan F, Yeh CK, Zeng X, Diao X, Hu Y, Chen S, Chen X, Zheng H.

Int J Nanomedicine. 2017 Aug 9;12:5613-5629. doi: 10.2147/IJN.S136401. eCollection 2017.


Antiangiogenic-targeting drug-loaded microbubbles combined with focused ultrasound for glioma treatment.

Fan CH, Ting CY, Liu HL, Huang CY, Hsieh HY, Yen TC, Wei KC, Yeh CK.

Biomaterials. 2013 Mar;34(8):2142-55. doi: 10.1016/j.biomaterials.2012.11.048. Epub 2012 Dec 14.


Magnetic-resonance imaging for kinetic analysis of permeability changes during focused ultrasound-induced blood-brain barrier opening and brain drug delivery.

Chai WY, Chu PC, Tsai MY, Lin YC, Wang JJ, Wei KC, Wai YY, Liu HL.

J Control Release. 2014 Oct 28;192:1-9. doi: 10.1016/j.jconrel.2014.06.023. Epub 2014 Jun 23.


Mechanisms of enhanced antiglioma efficacy of polysorbate 80-modified paclitaxel-loaded PLGA nanoparticles by focused ultrasound.

Li Y, Wu M, Zhang N, Tang C, Jiang P, Liu X, Yan F, Zheng H.

J Cell Mol Med. 2018 Sep;22(9):4171-4182. doi: 10.1111/jcmm.13695. Epub 2018 Jun 29.


Prolonged survival upon ultrasound-enhanced doxorubicin delivery in two syngenic glioblastoma mouse models.

Kovacs Z, Werner B, Rassi A, Sass JO, Martin-Fiori E, Bernasconi M.

J Control Release. 2014 Aug 10;187:74-82. doi: 10.1016/j.jconrel.2014.05.033. Epub 2014 May 27. Erratum in: J Control Release. 2014 Oct 28;192:294.


Targeted drug delivery with focused ultrasound-induced blood-brain barrier opening using acoustically-activated nanodroplets.

Chen CC, Sheeran PS, Wu SY, Olumolade OO, Dayton PA, Konofagou EE.

J Control Release. 2013 Dec 28;172(3):795-804. doi: 10.1016/j.jconrel.2013.09.025. Epub 2013 Oct 2.


Theranostic Strategy of Focused Ultrasound Induced Blood-Brain Barrier Opening for CNS Disease Treatment.

Chen KT, Wei KC, Liu HL.

Front Pharmacol. 2019 Feb 7;10:86. doi: 10.3389/fphar.2019.00086. eCollection 2019. Review.


Focused ultrasound-induced blood-brain barrier opening for non-viral, non-invasive, and targeted gene delivery.

Lin CY, Hsieh HY, Pitt WG, Huang CY, Tseng IC, Yeh CK, Wei KC, Liu HL.

J Control Release. 2015 Aug 28;212:1-9. doi: 10.1016/j.jconrel.2015.06.010. Epub 2015 Jun 11.


Drug-loaded bubbles with matched focused ultrasound excitation for concurrent blood-brain barrier opening and brain-tumor drug delivery.

Fan CH, Ting CY, Chang YC, Wei KC, Liu HL, Yeh CK.

Acta Biomater. 2015 Mar;15:89-101. doi: 10.1016/j.actbio.2014.12.026. Epub 2015 Jan 7.


Folate-conjugated gene-carrying microbubbles with focused ultrasound for concurrent blood-brain barrier opening and local gene delivery.

Fan CH, Chang EL, Ting CY, Lin YC, Liao EC, Huang CY, Chang YC, Chan HL, Wei KC, Yeh CK.

Biomaterials. 2016 Nov;106:46-57. doi: 10.1016/j.biomaterials.2016.08.017. Epub 2016 Aug 12.


Brain tumor-targeted delivery and therapy by focused ultrasound introduced doxorubicin-loaded cationic liposomes.

Lin Q, Mao KL, Tian FR, Yang JJ, Chen PP, Xu J, Fan ZL, Zhao YP, Li WF, Zheng L, Zhao YZ, Lu CT.

Cancer Chemother Pharmacol. 2016 Feb;77(2):269-80. doi: 10.1007/s00280-015-2926-1. Epub 2015 Dec 14.


Trans-cranial opening of the blood-brain barrier in targeted regions using a stereotaxic brain atlas and focused ultrasound energy.

Bing C, Ladouceur-Wodzak M, Wanner CR, Shelton JM, Richardson JA, Chopra R.

J Ther Ultrasound. 2014 Aug 4;2:13. doi: 10.1186/2050-5736-2-13. eCollection 2014.


Contrast-enhanced ultrasound imaging for the detection of focused ultrasound-induced blood-brain barrier opening.

Fan CH, Lin WH, Ting CY, Chai WY, Yen TC, Liu HL, Yeh CK.

Theranostics. 2014 Aug 1;4(10):1014-25. doi: 10.7150/thno.9575. eCollection 2014.


Combining microbubbles and ultrasound for drug delivery to brain tumors: current progress and overview.

Liu HL, Fan CH, Ting CY, Yeh CK.

Theranostics. 2014 Feb 12;4(4):432-44. doi: 10.7150/thno.8074. eCollection 2014. Review.

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