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31760766,29248441,26408346,23958541,22052106,31352001,23719586,29367759,25127677,21859833,25623042,34302028,29363536,17804724,23999170,26257060,26722025,23308056,34547282,26771140,19028870,22549877,32029896,26279302,34859959,30510993,32428833,34311032,22287227,25683115,23689354,27941872,29059173,17360542,22665051,27215660,31300513,19629168,28461470,23887057,28639695,25042889,31078621,33009500,32768595,33388318,29651002,29621546,30989379,32360551,31046123,30154150,31843590,30705405,29490942,24607504,21984419,36271032,29273451,32279996,29604291,27318148,33537098,31310834,31268604,23019409,22113502,29050937,32393543,31330317,31490946,17114585,34303658,27506299,21684285,27244456,34922945,23598351,24075515,34973294,31313401,29433879,31545922,22234980,33864001,26166469,25248858,24462734,31263025,21996748,25311989,21455033,28473229,28934293,24998203,27523981,28837246,23828595,28738823,21084261,31276933,31923844,36231137,17591971,28057438,36351408,23302291,32794627,35743139,32717220,23555182,31505723,26297056,31649109,23891977,35626644,30185628,27639167,30135483,22264792,17114584,27659014,24469904,31057295,24026351,21856775,32541781,24803537,36180487,33052229,20303350,34249932,21926469,20807812,32709695,36367161,35562376,32778157,36970723,23989613,34021083,22266668,24713432,34001163,36775484,24954535,35418690,35247012,35316682,22784710,20452353,22140463,36151074,36107485,32606001,19440048,34695382,22469842,32277014,35681705,36443441,20018721,24944064,25199993,19292977,24550494,22541435,36241718,23761168,32810598,33230218,35663242,34345207,26438693,27546622,35428659,24902898,36453576,21699781,25261239,36802267,22684718,28874965,23645620,24216479,35229994,17652141,33839689,21311774,19878870,21042537,33079429,35907592,31920150,21984975,36262061,22806240,24953430,29364867,23712558,29153842,35501460,22374815,34792696,24608432,31526907,24278292,22945649,36375776,32882403,33801246,29249692,35088684,29142904,31969677,23980075,33949915,31941709,20959479,21262926,37143164,34100198,33824054,32368735,19387337,24178582,33244099,35082383,36848578,31685994,21075310,33509790,35302596,34044069,36614194,32251323,30918400,27775692,35732240,32291806,33649537,30250298,27087446,34599002,36210625,19147554,30468734,34531315,27764699,35604033,19501586,33674596,35510530,33087490,23355395,22698407,36624189,33115526,35478937,36741230,32791343,29279356,33833413,33915081,32593694,36782009,35472437,21750515,36715788,25906749,36178225,35271824,35646902,36216931,33422093,34583087,36741265,32179733,34735515,32580961,34009137,35352018,33099471,35701533,35286386,34998392,34943970,34580018,24755884,35454872,36882214,34518296,35850360,36382086,35579947,35867735,36824971,21738581,36384095,34276991,32542554,34052323,32039734,36619305,29229669,32569010,35346801,34262644,33882289,32046984,21163920,35231699,36291712,34133937,36592214,36644936,33501895,35219699,25322341,28752115,23102107,34046348,35333412,15894267,35686834,22509024,37081806,32580737,36563135,33110094,28031255,37030634,18621715,34944918,19896097,23943783,30266763,33448017,34117030,33668583,32341020,26077591,20725998,35247912,25261994,20814421,36209277,36534167,30386596,35879546,21481787,36069770,36378658,29051265,25843002,33489473,31369062,36579622,33670598,35189981,35972810,25283383,36055991,26883357,25371176,37140994,35121887,32694385,36077614,35093877,22221894,32433397,35120712,33603164,23077629,34968866,32887255,28510280,32829010,36514219,35821188,36078040,33643692,35474735,35127250,32929194,32029124,20944652,35839440,24290880,20631070,27058937,24856586,21611096,35320003,23438477,34649604,32475178,27453905,33060649,19631339,35525794,24062691,24670819,29564165,29693047,32200350,36291766,36754903,22898636,35980869,36473072,34733795,37152291,33810510,34875393,36828627,27308552,35684434,36582783,35409135,35205746,35005111,35760494,36138073,35838046,34662582,35681634,31428515,34859257,22446714,36341459,24466367,23506980,34356340,35295896,36617502,34771644,34049974,35326559,35626213,35141005,34579548,32816911,35988455,33608310,34439202,35565279,36118526,35159117,35114204,36207523,36573057,35159064,36036243,36711764,36908331,34680275,20335777,34440587,29721157,35800049,34031785,32775353,35071236,31032094,28042501,35204468,35047000,33505964,35008235,33409403,36266629,36590644,26155420,35114730,35243242,36848888,33467038,34944784,28751357,33917380,34830866,34136388,35418199,33807330,33796221,37057680,36946782,36551971,32859281,30792639,36618907,36912021,34940031,35982180,34503200,24474939,34680288,28282928,23544163,34703570,35740306,36230607,18589869,35149528,27239482,21589862,36829437,25352950,24058792,34079044,19164086,32355703,34795853,34112697,33589421,34516754,33654171[uid]

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Results by year

Year	Number of Results
2005	1
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2007	4
2008	3
2009	11
2010	14
2011	22
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2015	18
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2019	30
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517 results

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Page 1

Moderate alcohol intake promotes pancreatic ductal adenocarcinoma development in mice expressing oncogenic Kras.

Asahina K, Balog S, Hwang E, Moon E, Wan E, Skrypek K, Chen Y, Fernandez J, Romo J, Yang Q, Lai K, French SW, Tsukamoto H. Asahina K, et al. Am J Physiol Gastrointest Liver Physiol. 2020 Feb 1;318(2):G265-G276. doi: 10.1152/ajpgi.00218.2019. Epub 2019 Nov 25. Am J Physiol Gastrointest Liver Physiol. 2020. PMID: 31760766 Free PMC article.

Krüppel-like Factor 5, Increased in Pancreatic Ductal Adenocarcinoma, Promotes Proliferation, Acinar-to-Ductal Metaplasia, Pancreatic Intraepithelial Neoplasia, and Tumor Growth in Mice.

He P, Yang JW, Yang VW, Bialkowska AB. He P, et al. Gastroenterology. 2018 Apr;154(5):1494-1508.e13. doi: 10.1053/j.gastro.2017.12.005. Epub 2017 Dec 15. Gastroenterology. 2018. PMID: 29248441 Free PMC article.

Loss of Activin Receptor Type 1B Accelerates Development of Intraductal Papillary Mucinous Neoplasms in Mice With Activated KRAS.

Qiu W, Tang SM, Lee S, Turk AT, Sireci AN, Qiu A, Rose C, Xie C, Kitajewski J, Wen HJ, Crawford HC, Sims PA, Hruban RH, Remotti HE, Su GH. Qiu W, et al. Gastroenterology. 2016 Jan;150(1):218-228.e12. doi: 10.1053/j.gastro.2015.09.013. Epub 2015 Sep 25. Gastroenterology. 2016. PMID: 26408346 Free PMC article.

A high-fat diet activates oncogenic Kras and COX2 to induce development of pancreatic ductal adenocarcinoma in mice.

Philip B, Roland CL, Daniluk J, Liu Y, Chatterjee D, Gomez SB, Ji B, Huang H, Wang H, Fleming JB, Logsdon CD, Cruz-Monserrate Z. Philip B, et al. Gastroenterology. 2013 Dec;145(6):1449-58. doi: 10.1053/j.gastro.2013.08.018. Epub 2013 Aug 16. Gastroenterology. 2013. PMID: 23958541 Free PMC article.

RAGE gene deletion inhibits the development and progression of ductal neoplasia and prolongs survival in a murine model of pancreatic cancer.

DiNorcia J, Lee MK, Moroziewicz DN, Winner M, Suman P, Bao F, Remotti HE, Zou YS, Yan SF, Qiu W, Su GH, Schmidt AM, Allendorf JD. DiNorcia J, et al. J Gastrointest Surg. 2012 Jan;16(1):104-12; discussion 112. doi: 10.1007/s11605-011-1754-9. Epub 2011 Nov 4. J Gastrointest Surg. 2012. PMID: 22052106 Free PMC article.

Oncogenic KRAS Reduces Expression of FGF21 in Acinar Cells to Promote Pancreatic Tumorigenesis in Mice on a High-Fat Diet.

Luo Y, Yang Y, Liu M, Wang D, Wang F, Bi Y, Ji J, Li S, Liu Y, Chen R, Huang H, Wang X, Swidnicka-Siergiejko AK, Janowitz T, Beyaz S, Wang G, Xu S, Bialkowska AB, Luo CK, Pin CL, Liang G, Lu X, Wu M, Shroyer KR, Wolff RA, Plunkett W, Ji B, Li Z, Li E, Li X, Yang VW, Logsdon CD, Abbruzzese JL, Lu W. Luo Y, et al. Gastroenterology. 2019 Nov;157(5):1413-1428.e11. doi: 10.1053/j.gastro.2019.07.030. Epub 2019 Jul 25. Gastroenterology. 2019. PMID: 31352001 Free PMC article.

The conditional expression of KRAS G12D in mouse pancreas induces disorganization of endocrine islets prior the onset of ductal pre-cancerous lesions.

Gout J, Pommier RM, Vincent DF, Ripoche D, Goddard-Léon S, Colombe A, Treilleux I, Valcourt U, Tomasini R, Dufresne M, Bertolino P, Bartholin L. Gout J, et al. Pancreatology. 2013 May-Jun;13(3):191-5. doi: 10.1016/j.pan.2013.02.001. Epub 2013 Feb 18. Pancreatology. 2013. PMID: 23719586

Genetic and pharmacologic abrogation of Snail1 inhibits acinar-to-ductal metaplasia in precursor lesions of pancreatic ductal adenocarcinoma and pancreatic injury.

Fendrich V, Jendryschek F, Beeck S, Albers M, Lauth M, Esni F, Heeger K, Dengler J, Slater EP, Holler JPN, Baier A, Bartsch DK, Waldmann J. Fendrich V, et al. Oncogene. 2018 Apr;37(14):1845-1856. doi: 10.1038/s41388-017-0100-4. Epub 2018 Jan 25. Oncogene. 2018. PMID: 29367759

Nicotine promotes initiation and progression of KRAS-induced pancreatic cancer via Gata6-dependent dedifferentiation of acinar cells in mice.

Hermann PC, Sancho P, Cañamero M, Martinelli P, Madriles F, Michl P, Gress T, de Pascual R, Gandia L, Guerra C, Barbacid M, Wagner M, Vieira CR, Aicher A, Real FX, Sainz B Jr, Heeschen C. Hermann PC, et al. Gastroenterology. 2014 Nov;147(5):1119-33.e4. doi: 10.1053/j.gastro.2014.08.002. Epub 2014 Aug 12. Gastroenterology. 2014. PMID: 25127677

Inhibition of chronic pancreatitis and pancreatic intraepithelial neoplasia (PanIN) by capsaicin in LSL-KrasG12D/Pdx1-Cre mice.

Bai H, Li H, Zhang W, Matkowskyj KA, Liao J, Srivastava SK, Yang GY. Bai H, et al. Carcinogenesis. 2011 Nov;32(11):1689-96. doi: 10.1093/carcin/bgr191. Epub 2011 Aug 22. Carcinogenesis. 2011. PMID: 21859833 Free PMC article.

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