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Impact of ApoE Polymorphism and Physical Activity on Plasma Antioxidant Capability and Erythrocyte Membranes.

Piccarducci R, Daniele S, Fusi J, Chico L, Baldacci F, Siciliano G, Bonuccelli U, Franzoni F, Martini C.

Antioxidants (Basel). 2019 Nov 9;8(11). pii: E538. doi: 10.3390/antiox8110538.


[Expression of apolipoprotein E in Alzheimer's disease and its significance].

He SR, Liu DG, Wang S, Xia YJ.

Zhonghua Bing Li Xue Za Zhi. 2005 Sep;34(9):556-60. Chinese.


Profiles of β-Amyloid Peptides and Key Secretases in Brain Autopsy Samples Differ with Sex and APOE ε4 Status: Impact for Risk and Progression of Alzheimer Disease.

Nyarko JNK, Quartey MO, Pennington PR, Heistad RM, Dea D, Poirier J, Baker GB, Mousseau DD.

Neuroscience. 2018 Mar 1;373:20-36. doi: 10.1016/j.neuroscience.2018.01.005. Epub 2018 Jan 11.


α-Synuclein Aggregates with β-Amyloid or Tau in Human Red Blood Cells: Correlation with Antioxidant Capability and Physical Exercise in Human Healthy Subjects.

Daniele S, Pietrobono D, Fusi J, Iofrida C, Chico L, Petrozzi L, Gerfo AL, Baldacci F, Galetta F, Siciliano G, Bonuccelli U, Santoro G, Trincavelli ML, Franzoni F, Martini C.

Mol Neurobiol. 2018 Mar;55(3):2653-2675. doi: 10.1007/s12035-017-0523-5. Epub 2017 Apr 18.


Apolipoprotein E genotype and the diagnostic accuracy of cerebrospinal fluid biomarkers for Alzheimer disease.

Lautner R, Palmqvist S, Mattsson N, Andreasson U, Wallin A, Pålsson E, Jakobsson J, Herukka SK, Owenius R, Olsson B, Hampel H, Rujescu D, Ewers M, Landén M, Minthon L, Blennow K, Zetterberg H, Hansson O; Alzheimer’s Disease Neuroimaging Initiative.

JAMA Psychiatry. 2014 Oct;71(10):1183-91. doi: 10.1001/jamapsychiatry.2014.1060.


Cerebral β-amyloid deposition predicts HIV-associated neurocognitive disorders in APOE ε4 carriers.

Soontornniyomkij V, Moore DJ, Gouaux B, Soontornniyomkij B, Tatro ET, Umlauf A, Masliah E, Levine AJ, Singer EJ, Vinters HV, Gelman BB, Morgello S, Cherner M, Grant I, Achim CL.

AIDS. 2012 Nov 28;26(18):2327-35. doi: 10.1097/QAD.0b013e32835a117c.


Oxidative balance in Alzheimer's disease: relationship to APOE, Braak tangle stage, and the concentrations of soluble and insoluble amyloid-β.

Tayler H, Fraser T, Miners JS, Kehoe PG, Love S.

J Alzheimers Dis. 2010;22(4):1363-73. doi: 10.3233/JAD-2010-101368.


The apolipoprotein E ε4 allele plays pathological roles in AD through high protein expression and interaction with butyrylcholinesterase.

Darreh-Shori T, Modiri N, Blennow K, Baza S, Kamil C, Ahmed H, Andreasen N, Nordberg A.

Neurobiol Aging. 2011 Jul;32(7):1236-48. doi: 10.1016/j.neurobiolaging.2009.07.015. Epub 2009 Aug 26.


Total apolipoprotein E levels and specific isoform composition in cerebrospinal fluid and plasma from Alzheimer's disease patients and controls.

Martínez-Morillo E, Hansson O, Atagi Y, Bu G, Minthon L, Diamandis EP, Nielsen HM.

Acta Neuropathol. 2014 May;127(5):633-43. doi: 10.1007/s00401-014-1266-2. Epub 2014 Mar 15.


Apolipoprotein E-epsilon4 alleles in cerebral amyloid angiopathy and cerebrovascular pathology associated with Alzheimer's disease.

Premkumar DR, Cohen DL, Hedera P, Friedland RP, Kalaria RN.

Am J Pathol. 1996 Jun;148(6):2083-95.


Multiple Effect of APOE Genotype on Clinical and Neuroimaging Biomarkers Across Alzheimer's Disease Spectrum.

Liu Y, Tan L, Wang HF, Liu Y, Hao XK, Tan CC, Jiang T, Liu B, Zhang DQ, Yu JT; Alzheimer’s Disease Neuroimaging Initiative.

Mol Neurobiol. 2016 Sep;53(7):4539-47. doi: 10.1007/s12035-015-9388-7. Epub 2015 Aug 23.


Effects of APOE rs429358, rs7412 and GSTM1/GSTT1 Polymorphism on Plasma and Erythrocyte Antioxidant Parameters and Cognition in Old Chinese Adults.

Yuan L, Liu J, Dong L, Cai C, Wang S, Wang B, Xiao R.

Nutrients. 2015 Sep 24;7(10):8261-73. doi: 10.3390/nu7105391.


Interactive effects of physical activity and APOE-ε4 on white matter tract diffusivity in healthy elders.

Smith JC, Lancaster MA, Nielson KA, Woodard JL, Seidenberg M, Durgerian S, Sakaie K, Rao SM.

Neuroimage. 2016 May 1;131:102-12. doi: 10.1016/j.neuroimage.2015.08.007. Epub 2015 Aug 8.


Gene-environment interactions: lifetime cognitive activity, APOE genotype, and β-amyloid burden.

Wirth M, Villeneuve S, La Joie R, Marks SM, Jagust WJ.

J Neurosci. 2014 Jun 18;34(25):8612-7. doi: 10.1523/JNEUROSCI.4612-13.2014.


Apolipoprotein E co-localizes with newly formed amyloid beta-protein (Abeta) deposits lacking immunoreactivity against N-terminal epitopes of Abeta in a genotype-dependent manner.

Thal DR, Capetillo-Zarate E, Schultz C, Rüb U, Saido TC, Yamaguchi H, Haass C, Griffin WS, Del Tredici K, Braak H, Ghebremedhin E.

Acta Neuropathol. 2005 Nov;110(5):459-71. Epub 2005 Sep 30.


Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.

Castellano JM, Kim J, Stewart FR, Jiang H, DeMattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C, Goate AM, Bales KR, Paul SM, Bateman RJ, Holtzman DM.

Sci Transl Med. 2011 Jun 29;3(89):89ra57. doi: 10.1126/scitranslmed.3002156.


Blocking the apoE/Aβ interaction ameliorates Aβ-related pathology in APOE ε2 and ε4 targeted replacement Alzheimer model mice.

Pankiewicz JE, Guridi M, Kim J, Asuni AA, Sanchez S, Sullivan PM, Holtzman DM, Sadowski MJ.

Acta Neuropathol Commun. 2014 Jun 28;2:75. doi: 10.1186/s40478-014-0075-0.


Independent and Interactive Influences of the APOE Genotype and Beta-Amyloid Burden on Cognitive Function in Mild Cognitive Impairment.

Seo EH, Kim SH, Park SH, Kang SH, Choo IH; Alzheimer's Disease Neuroimaging Initiative.

J Korean Med Sci. 2016 Feb;31(2):286-95. doi: 10.3346/jkms.2016.31.2.286. Epub 2016 Jan 13.


Association of Apolipoprotein E ε4 With Transactive Response DNA-Binding Protein 43.

Wennberg AM, Tosakulwong N, Lesnick TG, Murray ME, Whitwell JL, Liesinger AM, Petrucelli L, Boeve BF, Parisi JE, Knopman DS, Petersen RC, Dickson DW, Josephs KA.

JAMA Neurol. 2018 Nov 1;75(11):1347-1354. doi: 10.1001/jamaneurol.2018.3139.


Cerebral beta-amyloid deposition is augmented by the -491AA promoter polymorphism in non-demented elderly individuals bearing the apolipoprotein E epsilon4 allele.

Pahnke J, Walker LC, Schroeder E, Vogelgesang S, Stausske D, Walther R, Warzok RW.

Acta Neuropathol. 2003 Jan;105(1):25-9. Epub 2002 Nov 5.


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