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Therapeutic Targeting of Cancer Stem Cells in Human Glioblastoma by Manipulating the Renin-Angiotensin System.

Tan DC, Roth IM, Wickremesekera AC, Davis PF, Kaye AH, Mantamadiotis T, Stylli SS, Tan ST.

Cells. 2019 Oct 31;8(11). pii: E1364. doi: 10.3390/cells8111364. Review.


Therapeutic Targeting of Cancer Stem Cells via Modulation of the Renin-Angiotensin System.

Roth IM, Wickremesekera AC, Wickremesekera SK, Davis PF, Tan ST.

Front Oncol. 2019 Aug 8;9:745. doi: 10.3389/fonc.2019.00745. eCollection 2019. Review.


Circulating tumor stem cells and glioblastoma: A review.

van Schaijik B, Wickremesekera AC, Mantamadiotis T, Kaye AH, Tan ST, Stylli SS, Itinteang T.

J Clin Neurosci. 2019 Mar;61:5-9. doi: 10.1016/j.jocn.2018.12.019. Epub 2019 Jan 6. Review.


Glioblastoma Multiforme Cancer Stem Cells Express Components of the Renin-Angiotensin System.

Bradshaw AR, Wickremesekera AC, Brasch HD, Chibnall AM, Davis PF, Tan ST, Itinteang T.

Front Surg. 2016 Sep 27;3:51. eCollection 2016.


Mutual Influence of ROS, pH, and CLIC1 Membrane Protein in the Regulation of G1-S Phase Progression in Human Glioblastoma Stem Cells.

Peretti M, Raciti FM, Carlini V, Verduci I, Sertic S, Barozzi S, Garré M, Pattarozzi A, Daga A, Barbieri F, Costa A, Florio T, Mazzanti M.

Mol Cancer Ther. 2018 Nov;17(11):2451-2461. doi: 10.1158/1535-7163.MCT-17-1223. Epub 2018 Aug 22.


A novel berbamine derivative inhibits cell viability and induces apoptosis in cancer stem-like cells of human glioblastoma, via up-regulation of miRNA-4284 and JNK/AP-1 signaling.

Yang F, Nam S, Brown CE, Zhao R, Starr R, Ma Y, Xie J, Horne DA, Malkas LH, Jove R, Hickey RJ.

PLoS One. 2014 Apr 14;9(4):e94443. doi: 10.1371/journal.pone.0094443. eCollection 2014. Erratum in: PLoS One. 2014;9(6):e100708. Ma, Yuelong [added]; Xie, Jun [added].


Concise review: bullseye: targeting cancer stem cells to improve the treatment of gliomas by repurposing disulfiram.

Triscott J, Rose Pambid M, Dunn SE.

Stem Cells. 2015 Apr;33(4):1042-6. doi: 10.1002/stem.1956. Review.


Cancer Stem Cells in Moderately Differentiated Buccal Mucosal Squamous Cell Carcinoma Express Components of the Renin-Angiotensin System.

Featherston T, Yu HH, Dunne JC, Chibnall AM, Brasch HD, Davis PF, Tan ST, Itinteang T.

Front Surg. 2016 Sep 27;3:52. eCollection 2016.


Sox2, a stemness gene, regulates tumor-initiating and drug-resistant properties in CD133-positive glioblastoma stem cells.

Song WS, Yang YP, Huang CS, Lu KH, Liu WH, Wu WW, Lee YY, Lo WL, Lee SD, Chen YW, Huang PI, Chen MT.

J Chin Med Assoc. 2016 Oct;79(10):538-45. doi: 10.1016/j.jcma.2016.03.010. Epub 2016 Aug 13.


Cancer Stem Cells in Oral Cavity Squamous Cell Carcinoma: A Review.

Baillie R, Tan ST, Itinteang T.

Front Oncol. 2017 Jun 2;7:112. doi: 10.3389/fonc.2017.00112. eCollection 2017. Review.


Glioblastoma cancer stem cells: heterogeneity, microenvironment and related therapeutic strategies.

Denysenko T, Gennero L, Roos MA, Melcarne A, Juenemann C, Faccani G, Morra I, Cavallo G, Reguzzi S, Pescarmona G, Ponzetto A.

Cell Biochem Funct. 2010 Jul;28(5):343-51. doi: 10.1002/cbf.1666. Review.


Proteins of the Wnt signaling pathway as targets for the regulation of CD133+ cancer stem cells in glioblastoma.

Shevchenko V, Arnotskaya N, Korneyko M, Zaytsev S, Khotimchenko Y, Sharma H, Bryukhovetskiy I.

Oncol Rep. 2019 May;41(5):3080-3088. doi: 10.3892/or.2019.7043. Epub 2019 Mar 5.


Insights in the immunobiology of glioblastoma.

Strepkos D, Markouli M, Klonou A, Piperi C, Papavassiliou AG.

J Mol Med (Berl). 2020 Jan;98(1):1-10. doi: 10.1007/s00109-019-01835-4. Epub 2019 Oct 24. Review.


Constitutive activation of signal transducer and activator of transcription 3 (STAT3) and nuclear factor κB signaling in glioblastoma cancer stem cells regulates the Notch pathway.

Garner JM, Fan M, Yang CH, Du Z, Sims M, Davidoff AM, Pfeffer LM.

J Biol Chem. 2013 Sep 6;288(36):26167-76. doi: 10.1074/jbc.M113.477950. Epub 2013 Jul 31.


Response of primary glioblastoma cells to therapy is patient specific and independent of cancer stem cell phenotype.

Fouse SD, Nakamura JL, James CD, Chang S, Costello JF.

Neuro Oncol. 2014 Mar;16(3):361-71. doi: 10.1093/neuonc/not223. Epub 2013 Dec 4.


Brain malignancies: Glioblastoma and brain metastases.

Lah TT, Novak M, Breznik B.

Semin Cancer Biol. 2019 Oct 22. pii: S1044-579X(19)30227-5. doi: 10.1016/j.semcancer.2019.10.010. [Epub ahead of print] Review.


Targeting cancer stem cells for treatment of glioblastoma multiforme.

Cho DY, Lin SZ, Yang WK, Lee HC, Hsu DM, Lin HL, Chen CC, Liu CL, Lee WY, Ho LH.

Cell Transplant. 2013;22(4):731-9. doi: 10.3727/096368912X655136. Review.


The Akt/mTOR pathway in cancer stem/progenitor cells is a potential therapeutic target for glioblastoma and neuroblastoma.

Bahmad HF, Mouhieddine TH, Chalhoub RM, Assi S, Araji T, Chamaa F, Itani MM, Nokkari A, Kobeissy F, Daoud G, Abou-Kheir W.

Oncotarget. 2018 Sep 11;9(71):33549-33561. doi: 10.18632/oncotarget.26088. eCollection 2018 Sep 11.


Prediction of posthepatectomy recurrence of hepatocellular carcinoma by circulating cancer stem cells: a prospective study.

Fan ST, Yang ZF, Ho DW, Ng MN, Yu WC, Wong J.

Ann Surg. 2011 Oct;254(4):569-76. doi: 10.1097/SLA.0b013e3182300a1d.


Renin angiotensin system and its role in biomarkers and treatment in gliomas.

Perdomo-Pantoja A, Mejía-Pérez SI, Gómez-Flores-Ramos L, Lara-Velazquez M, Orillac C, Gómez-Amador JL, Wegman-Ostrosky T.

J Neurooncol. 2018 May;138(1):1-15. doi: 10.1007/s11060-018-2789-5. Epub 2018 Feb 16. Review.


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