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Items: 1 to 20 of 95


Nanotherapy Targeting NF-κB Attenuates Acute Pain After Joint Injury.

Yan H, Duan X, Collins KH, Springer LE, Guilak F, Wickline SA, Rai MF, Pan H, Pham CTN.

Precis Nanomed. 2019;2(1):245-248. doi: 10.33218/prnano2(1).181129.1. Epub 2019 Jan 12.


Suppression of NF-κB activity via nanoparticle-based siRNA delivery alters early cartilage responses to injury.

Yan H, Duan X, Pan H, Holguin N, Rai MF, Akk A, Springer LE, Wickline SA, Sandell LJ, Pham CT.

Proc Natl Acad Sci U S A. 2016 Oct 11;113(41):E6199-E6208. Epub 2016 Sep 28. Erratum in: Proc Natl Acad Sci U S A. 2017 May 9;114(19):E3871.


Malvidin attenuates pain and inflammation in rats with osteoarthritis by suppressing NF-κB signaling pathway.

Dai T, Shi K, Chen G, Shen Y, Pan T.

Inflamm Res. 2017 Dec;66(12):1075-1084. doi: 10.1007/s00011-017-1087-6. Epub 2017 Aug 29.


Hydrogen-Rich Saline Attenuated Subarachnoid Hemorrhage-Induced Early Brain Injury in Rats by Suppressing Inflammatory Response: Possible Involvement of NF-κB Pathway and NLRP3 Inflammasome.

Shao A, Wu H, Hong Y, Tu S, Sun X, Wu Q, Zhao Q, Zhang J, Sheng J.

Mol Neurobiol. 2016 Jul;53(5):3462-3476. doi: 10.1007/s12035-015-9242-y. Epub 2015 Jun 20.


Polyphyllin I Ameliorates Collagen-Induced Arthritis by Suppressing the Inflammation Response in Macrophages Through the NF-κB Pathway.

Wang Q, Zhou X, Zhao Y, Xiao J, Lu Y, Shi Q, Wang Y, Wang H, Liang Q.

Front Immunol. 2018 Sep 27;9:2091. doi: 10.3389/fimmu.2018.02091. eCollection 2018.


Isoliquiritigenin attenuates LPS-induced AKI by suppression of inflammation involving NF-κB pathway.

Tang Y, Wang C, Wang Y, Zhang J, Wang F, Li L, Meng X, Li G, Li Y, Wang L.

Am J Transl Res. 2018 Dec 15;10(12):4141-4151. eCollection 2018.


Nobiletin Inhibits IL-1β-Induced Inflammation in Chondrocytes via Suppression of NF-κB Signaling and Attenuates Osteoarthritis in Mice.

Lin Z, Wu D, Huang L, Jiang C, Pan T, Kang X, Pan J.

Front Pharmacol. 2019 May 31;10:570. doi: 10.3389/fphar.2019.00570. eCollection 2019.


Valproic acid attenuates traumatic spinal cord injury-induced inflammation via STAT1 and NF-κB pathway dependent of HDAC3.

Chen S, Ye J, Chen X, Shi J, Wu W, Lin W, Lin W, Li Y, Fu H, Li S.

J Neuroinflammation. 2018 May 18;15(1):150. doi: 10.1186/s12974-018-1193-6.


Anemonin attenuates osteoarthritis progression through inhibiting the activation of IL-1β/NF-κB pathway.

Wang Z, Huang J, Zhou S, Luo F, Xu W, Wang Q, Tan Q, Chen L, Wang J, Chen H, Chen L, Xie Y, Du X.

J Cell Mol Med. 2017 Dec;21(12):3231-3243. doi: 10.1111/jcmm.13227. Epub 2017 Jun 23.


Pogostone attenuates TNF-α-induced injury in A549 cells via inhibiting NF-κB and activating Nrf2 pathways.

Yang HM, Zhuo JY, Sun CY, Nie J, Yuan J, Liu YL, Lin RF, Lai XP, Su ZR, Li YC.

Int Immunopharmacol. 2018 Sep;62:15-22. doi: 10.1016/j.intimp.2018.06.029. Epub 2018 Jun 30.


In vivo luminescence imaging of NF-κB activity and serum cytokine levels predict pain sensitivities in a rodent model of osteoarthritis.

Bowles RD, Mata BA, Bell RD, Mwangi TK, Huebner JL, Kraus VB, Setton LA.

Arthritis Rheumatol. 2014 Mar;66(3):637-46. doi: 10.1002/art.38279.


Small interfering RNA targeting NF-κB attenuates lipopolysaccharide-induced acute lung injury in rats.

Li N, Song Y, Zhao W, Han T, Lin S, Ramirez O, Liang L.

BMC Physiol. 2016 Dec 28;16(1):7. doi: 10.1186/s12899-016-0027-y.


The peroxisome proliferator-activated receptor γ agonist pioglitazone prevents NF-κB activation in cisplatin nephrotoxicity through the reduction of p65 acetylation via the AMPK-SIRT1/p300 pathway.

Zhang J, Zhang Y, Xiao F, Liu Y, Wang J, Gao H, Rong S, Yao Y, Li J, Xu G.

Biochem Pharmacol. 2016 Feb 1;101:100-11. doi: 10.1016/j.bcp.2015.11.027. Epub 2015 Dec 7.


Baicalin suppresses IL-1β-induced expression of inflammatory cytokines via blocking NF-κB in human osteoarthritis chondrocytes and shows protective effect in mice osteoarthritis models.

Chen C, Zhang C, Cai L, Xie H, Hu W, Wang T, Lu D, Chen H.

Int Immunopharmacol. 2017 Nov;52:218-226. doi: 10.1016/j.intimp.2017.09.017. Epub 2017 Sep 22.


Nuclear factor (NF)-κB and its associated pathways are major molecular regulators of blood-induced joint damage in a murine model of hemophilia.

Sen D, Chapla A, Walter N, Daniel V, Srivastava A, Jayandharan GR.

J Thromb Haemost. 2013 Feb;11(2):293-306. doi: 10.1111/jth.12101.


Omega-3 polyunsaturated fatty acid supplementation attenuates microglial-induced inflammation by inhibiting the HMGB1/TLR4/NF-κB pathway following experimental traumatic brain injury.

Chen X, Wu S, Chen C, Xie B, Fang Z, Hu W, Chen J, Fu H, He H.

J Neuroinflammation. 2017 Jul 24;14(1):143. doi: 10.1186/s12974-017-0917-3.


Paeonol protects endotoxin-induced acute kidney injury: potential mechanism of inhibiting TLR4-NF-κB signal pathway.

Fan HY, Qi D, Yu C, Zhao F, Liu T, Zhang ZK, Yang MY, Zhang LM, Chen DQ, Du Y.

Oncotarget. 2016 Jun 28;7(26):39497-39510. doi: 10.18632/oncotarget.8347.


Pioglitazone inhibits advanced glycation end product-induced matrix metalloproteinases and apoptosis by suppressing the activation of MAPK and NF-κB.

Zhang HB, Zhang Y, Chen C, Li YQ, Ma C, Wang ZJ.

Apoptosis. 2016 Oct;21(10):1082-93. doi: 10.1007/s10495-016-1280-z.


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