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Items: 1 to 20 of 102

1.

In vivo characterization of enTRinsic™ drug delivery technology capsule after intake in fed state: A cross-validation approach using salivary tracer technique in comparison to MRI.

Sager M, Grimm M, Aude P, Schick P, Merdivan S, Hasan M, Kromrey ML, Sivert A, Benameur H, Koziolek M, Tzvetkov MV, Weitschies W.

J Control Release. 2019 Nov 10;313:24-32. doi: 10.1016/j.jconrel.2019.10.023. Epub 2019 Oct 15.

PMID:
31626859
2.

Combined Application of MRI and the Salivary Tracer Technique to Determine the in Vivo Disintegration Time of Immediate Release Formulation Administered to Healthy, Fasted Subjects.

Sager M, Grimm M, Jedamzik P, Merdivan S, Kromrey ML, Hasan M, Koziolek M, Tzvetkov MV, Weitschies W.

Mol Pharm. 2019 Apr 1;16(4):1782-1786. doi: 10.1021/acs.molpharmaceut.8b01320. Epub 2019 Mar 8.

PMID:
30821987
3.

Low dose caffeine as a salivary tracer for the determination of gastric water emptying in fed and fasted state: A MRI validation study.

Sager M, Jedamzik P, Merdivan S, Grimm M, Schneider F, Kromrey ML, Hasan M, Oswald S, Kühn J, Koziolek M, Weitschies W.

Eur J Pharm Biopharm. 2018 Jun;127:443-452. doi: 10.1016/j.ejpb.2018.03.011. Epub 2018 Mar 27.

PMID:
29602018
4.

Characterization of the gastrointestinal transit and disintegration behavior of floating and sinking acid-resistant capsules using a novel MRI labeling technique.

Grimm M, Ball K, Scholz E, Schneider F, Sivert A, Benameur H, Kromrey ML, Kühn JP, Weitschies W.

Eur J Pharm Sci. 2019 Mar 1;129:163-172. doi: 10.1016/j.ejps.2019.01.012. Epub 2019 Jan 10.

PMID:
30639530
5.

Evaluation of intestinal pressure-controlled colon delivery capsule containing caffeine as a model drug in human volunteers.

Muraoka M, Hu Z, Shimokawa T, Sekino S, Kurogoshi R, Kuboi Y, Yoshikawa Y, Takada K.

J Control Release. 1998 Mar 2;52(1-2):119-29.

PMID:
9685942
6.
8.

Effects of food on a gastrically degraded drug: azithromycin fast-dissolving gelatin capsules and HPMC capsules.

Curatolo W, Liu P, Johnson BA, Hausberger A, Quan E, Vendola T, Vatsaraj N, Foulds G, Vincent J, Chandra R.

Pharm Res. 2011 Jul;28(7):1531-9. doi: 10.1007/s11095-011-0386-9. Epub 2011 Feb 18.

PMID:
21331473
9.

Characterization of the behavior of alginate-based microcapsules in vitro and in vivo.

Anschütz M, Garbacz G, Kosch O, Donath F, Wiedmann J, Hoeckh W, Trahms L, Schug B, Weitschies W, Blume H.

Int J Clin Pharmacol Ther. 2009 Sep;47(9):556-63.

PMID:
19761714
10.

Evaluation of gastrointestinal transit characteristics of oral patch preparation using caffeine as a model drug in human volunteers.

Eaimtrakarn S, Prasad YV, Puthli SP, Yoshikawa Y, Shibata N, Takada K.

Drug Metab Pharmacokinet. 2002;17(4):284-91.

11.

Investigation of human pharmacoscintigraphic behavior of two tablets and a capsule formulation of a high dose, poorly water soluble/highly permeable drug (efavirenz).

Gao JZh, Hussain MA, Motheram R, Gray DA, Benedek IH, Fiske WD, Doll WJ, Sandefer E, Page RC, Digenis GA.

J Pharm Sci. 2007 Nov;96(11):2970-7.

PMID:
17542016
12.

In Vivo Dissolution and Systemic Absorption of Immediate Release Ibuprofen in Human Gastrointestinal Tract under Fed and Fasted Conditions.

Koenigsknecht MJ, Baker JR, Wen B, Frances A, Zhang H, Yu A, Zhao T, Tsume Y, Pai MP, Bleske BE, Zhang X, Lionberger R, Lee A, Amidon GL, Hasler WL, Sun D.

Mol Pharm. 2017 Dec 4;14(12):4295-4304. doi: 10.1021/acs.molpharmaceut.7b00425. Epub 2017 Oct 5.

PMID:
28937221
13.

Error occurred: cannot get document summary

PMID:
31817867

14.

Formulation of Broccoli Sprout Powder in Gastro-Resistant Capsules Protects against the Acidic pH of the Stomach In Vitro but Does Not Increase Isothiocyanate Bioavailability In Vivo.

Zawari M, Poller B, Walker G, Pearson A, Hampton M, Carr AC.

Antioxidants (Basel). 2019 Sep 1;8(9). pii: E359. doi: 10.3390/antiox8090359.

15.

Gastro intestinal tracking and gastric emptying of solid dosage forms in rats using X-ray imaging.

Saphier S, Rosner A, Brandeis R, Karton Y.

Int J Pharm. 2010 Mar 30;388(1-2):190-5. doi: 10.1016/j.ijpharm.2010.01.001. Epub 2010 Jan 14.

PMID:
20079410
16.
17.

Comparison of the rates of disintegration, gastric emptying, and drug absorption following administration of a new and a conventional paracetamol formulation, using gamma scintigraphy.

Kelly K, O'Mahony B, Lindsay B, Jones T, Grattan TJ, Rostami-Hodjegan A, Stevens HN, Wilson CG.

Pharm Res. 2003 Oct;20(10):1668-73.

PMID:
14620524
18.

Scintigraphic evaluation of a new capsule-type colon specific drug delivery system in healthy volunteers.

Ishibashi T, Pitcairn GR, Yoshino H, Mizobe M, Wilding IR.

J Pharm Sci. 1998 May;87(5):531-5.

PMID:
9572900
19.

In vivo evaluation of the absorption and gastrointestinal transit of avitriptan in fed and fasted subjects using gamma scintigraphy.

Marathe PH, Sandefer EP, Kollia GE, Greene DS, Barbhaiya RH, Lipper RA, Page RC, Doll WJ, Ryo UY, Digenis GA.

J Pharmacokinet Biopharm. 1998 Feb;26(1):1-20.

PMID:
9773390
20.

Intragastric behavior and absorption kinetics of a normal and "floating" modified-release capsule of isradipine under fasted and fed conditions.

Mazer N, Abisch E, Gfeller JC, Laplanche R, Bauerfeind P, Cucala M, Lukachich M, Blum A.

J Pharm Sci. 1988 Aug;77(8):647-57.

PMID:
2974884

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