Similar articles for PMID: 31577424

Year	Number of Results
1996	1
1999	1
2001	1
2003	2
2004	1
2005	5
2006	4
2007	1
2008	3
2009	5
2010	5
2011	3
2012	4
2013	5
2014	8
2015	6
2016	8
2017	12
2018	8
2019	8
2020	2
2021	2
2022	1
2023	1
2024	0

1

Determinants of Active-Site Inhibitor Interaction with HIV-1 RNase H.

Xi Z, Wang Z, Sarafianos SG, Myshakina NS, Ishima R. Xi Z, et al. ACS Infect Dis. 2019 Nov 8;5(11):1963-1974. doi: 10.1021/acsinfecdis.9b00300. Epub 2019 Oct 2. ACS Infect Dis. 2019. PMID: 31577424 Free PMC article.

2

A 2-Hydroxyisoquinoline-1,3-Dione Active-Site RNase H Inhibitor Binds in Multiple Modes to HIV-1 Reverse Transcriptase.

Kirby KA, Myshakina NA, Christen MT, Chen YL, Schmidt HA, Huber AD, Xi Z, Kim S, Rao RK, Kramer ST, Yang Q, Singh K, Parniak MA, Wang Z, Ishima R, Sarafianos SG. Kirby KA, et al. Antimicrob Agents Chemother. 2017 Sep 22;61(10):e01351-17. doi: 10.1128/AAC.01351-17. Print 2017 Oct. Antimicrob Agents Chemother. 2017. PMID: 28760905 Free PMC article.

3

Structural basis of the allosteric inhibitor interaction on the HIV-1 reverse transcriptase RNase H domain.

Christen MT, Menon L, Myshakina NS, Ahn J, Parniak MA, Ishima R. Christen MT, et al. Chem Biol Drug Des. 2012 Nov;80(5):706-16. doi: 10.1111/cbdd.12010. Epub 2012 Aug 31. Chem Biol Drug Des. 2012. PMID: 22846652 Free PMC article.

4

Entire-Dataset Analysis of NMR Fast-Exchange Titration Spectra: A Mg²⁺ Titration Analysis for HIV-1 Ribonuclease H Domain.

Karki I, Christen MT, Spiriti J, Slack RL, Oda M, Kanaori K, Zuckerman DM, Ishima R. Karki I, et al. J Phys Chem B. 2016 Dec 15;120(49):12420-12431. doi: 10.1021/acs.jpcb.6b08323. Epub 2016 Dec 5. J Phys Chem B. 2016. PMID: 27973819 Free PMC article.

5

Quinolinonyl Non-Diketo Acid Derivatives as Inhibitors of HIV-1 Ribonuclease H and Polymerase Functions of Reverse Transcriptase.

Messore A, Corona A, Madia VN, Saccoliti F, Tudino V, De Leo A, Ialongo D, Scipione L, De Vita D, Amendola G, Novellino E, Cosconati S, Métifiot M, Andreola ML, Esposito F, Grandi N, Tramontano E, Costi R, Di Santo R. Messore A, et al. J Med Chem. 2021 Jun 24;64(12):8579-8598. doi: 10.1021/acs.jmedchem.1c00535. Epub 2021 Jun 9. J Med Chem. 2021. PMID: 34106711 Free PMC article.

6

Pharmacophore-based design of novel 3-hydroxypyrimidine-2,4-dione subtypes as inhibitors of HIV reverse transcriptase-associated RNase H: Tolerance of a nonflexible linker.

Tang J, Do HT, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Parniak MA, Sarafianos SG, Wang Z. Tang J, et al. Eur J Med Chem. 2019 Mar 15;166:390-399. doi: 10.1016/j.ejmech.2019.01.081. Epub 2019 Feb 2. Eur J Med Chem. 2019. PMID: 30739822 Free PMC article.

7

Structural basis for the inhibition of RNase H activity of HIV-1 reverse transcriptase by RNase H active site-directed inhibitors.

Su HP, Yan Y, Prasad GS, Smith RF, Daniels CL, Abeywickrema PD, Reid JC, Loughran HM, Kornienko M, Sharma S, Grobler JA, Xu B, Sardana V, Allison TJ, Williams PD, Darke PL, Hazuda DJ, Munshi S. Su HP, et al. J Virol. 2010 Aug;84(15):7625-33. doi: 10.1128/JVI.00353-10. Epub 2010 May 19. J Virol. 2010. PMID: 20484498 Free PMC article.

8

Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase.

Tang J, Vernekar SKV, Chen YL, Miller L, Huber AD, Myshakina N, Sarafianos SG, Parniak MA, Wang Z. Tang J, et al. Eur J Med Chem. 2017 Jun 16;133:85-96. doi: 10.1016/j.ejmech.2017.03.059. Epub 2017 Mar 29. Eur J Med Chem. 2017. PMID: 28384548 Free PMC article.

9

Recent progress in the research of small molecule HIV-1 RNase H inhibitors.

Cao L, Song W, De Clercq E, Zhan P, Liu X. Cao L, et al. Curr Med Chem. 2014 Jun;21(17):1956-67. doi: 10.2174/0929867321666140120121158. Curr Med Chem. 2014. PMID: 24438523 Review.

10

6-Biphenylmethyl-3-hydroxypyrimidine-2,4-diones potently and selectively inhibited HIV reverse transcriptase-associated RNase H.

Wang L, Tang J, Huber AD, Casey MC, Kirby KA, Wilson DJ, Kankanala J, Parniak MA, Sarafianos SG, Wang Z. Wang L, et al. Eur J Med Chem. 2018 Aug 5;156:680-691. doi: 10.1016/j.ejmech.2018.07.035. Epub 2018 Jul 17. Eur J Med Chem. 2018. PMID: 30031978 Free PMC article.

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