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Items: 1 to 20 of 101

1.

Polygala tenuifolia-Acori tatarinowii herbal pair as an inspiration for substituted cinnamic α-asaronol esters: Design, synthesis, anticonvulsant activity, and inhibition of lactate dehydrogenase study.

Bai Y, He X, Bai Y, Sun Y, Zhao Z, Chen X, Li B, Xie J, Li Y, Jia P, Meng X, Zhao Y, Ding Y, Xiao C, Wang S, Yu J, Liao S, Zhang Y, Zhu Z, Zhang Q, Zhao Y, Qin F, Zhang Y, Wei X, Zeng M, Liang J, Cuan Y, Shan G, Fan TP, Wu B, Zheng X.

Eur J Med Chem. 2019 Sep 6;183:111650. doi: 10.1016/j.ejmech.2019.111650. [Epub ahead of print]

PMID:
31539780
2.

Excavating precursors from the traditional Chinese herb Polygala tenuifolia and Gastrodia elata: Synthesis, anticonvulsant activity evaluation of 3,4,5-trimethoxycinnamic acid (TMCA) ester derivatives.

Zhao Z, Bai Y, Xie J, Chen X, He X, Sun Y, Bai Y, Zhang Y, Wu S, Zheng X.

Bioorg Chem. 2019 Jul;88:102832. doi: 10.1016/j.bioorg.2019.03.006. Epub 2019 Mar 4.

PMID:
31102809
3.

Anticonvulsant activities of α-asaronol ((E)-3'-hydroxyasarone), an active constituent derived from α-asarone.

He X, Bai Y, Zeng M, Zhao Z, Zhang Q, Xu N, Qin F, Wei X, Zhao M, Wu N, Li Z, Zhang Y, Fan TP, Zheng X.

Pharmacol Rep. 2018 Feb;70(1):69-74. doi: 10.1016/j.pharep.2017.08.004. Epub 2017 Aug 31.

PMID:
29331789
4.

[Research on network pharmacology of Acori Tatarinowii Rhizoma combined with Curcumae Radix in treating epilepsy].

Wang Q, Yuan LL, Zhang YL, Fan WT.

Zhongguo Zhong Yao Za Zhi. 2019 Jul;44(13):2701-2708. doi: 10.19540/j.cnki.cjcmm.20190416.403. Chinese.

PMID:
31359680
5.
6.

Discrimination of Acori Tatarinowii Rhizoma and Acori Calami Rhizoma based on quantitative gas chromatographic fingerprints and chemometric methods.

Zhang X, Yi L, Deng B, Chen L, Shi S, Zhuang Y, Zhang Y.

J Sep Sci. 2015 Dec;38(23):4078-85. doi: 10.1002/jssc.201500730. Epub 2015 Oct 27.

PMID:
26396060
7.

Optimizing the compatibility of paired-herb in an ancient Chinese herbal decoction Kai-Xin-San in activating neurofilament expression in cultured PC12 cells.

Yan L, Xu SL, Zhu KY, Lam KY, Xin G, Maiwulanjiang M, Li N, Dong TT, Lin H, Tsim KW.

J Ethnopharmacol. 2015 Mar 13;162:155-62. doi: 10.1016/j.jep.2014.12.049. Epub 2015 Jan 2.

PMID:
25560671
8.

[UPLC/Q-TOF MS-Based Metabolomics Analysis of Chemical uiterences in Different Polygala tenuifolia Varieties].

Bai L, Xu XS, Zhang FS, Peng B, Zeng ZP, Tian HL, Qin XM.

Zhong Yao Cai. 2015 Sep;38(9):1819-24. Chinese.

PMID:
26930975
9.

[Roles and mechanisms of traditional Chinese medicine and its active ingredients in treating epilepsy].

Yuan X, Li Z, Wang XT, Li XY, Hua H, Li XC, Tang RX, Liu XM.

Zhongguo Zhong Yao Za Zhi. 2019 Jan;44(1):9-18. doi: 10.19540/j.cnki.cjcmm.20181012.006. Review. Chinese.

PMID:
30868806
10.

[Rationality of commodity criteria and traditional breeding of Polygala tenuifolia based on agronomic traits and determination of chemical components].

Wang DD, Bai L, Xu XS, Zhang FS, Xing J, Jia JP, Tian HL, Qin XM.

Zhongguo Zhong Yao Za Zhi. 2016 Oct;41(20):3733-3740. doi: 10.4268/cjcmm20162006. Chinese.

PMID:
28929649
11.

Pharmacokinetics and tissue distribution evaluation of α-asaronol and its main metabolite in rats by HPLC method.

Sun Y, Bai Y, Zeng M, Chen X, Xie J, Li B, He X, Bai Y, Jia P, Meng X, Liang J, Wang S, Fan TP, Wu B, Zheng X.

J Pharm Biomed Anal. 2019 Aug 5;172:349-356. doi: 10.1016/j.jpba.2019.05.004. Epub 2019 May 3.

PMID:
31085397
12.
13.

The synthetic neuroactive steroid SGE-516 reduces seizure burden and improves survival in a Dravet syndrome mouse model.

Hawkins NA, Lewis M, Hammond RS, Doherty JJ, Kearney JA.

Sci Rep. 2017 Nov 10;7(1):15327. doi: 10.1038/s41598-017-15609-w.

14.

[Mechanism of Acori Tatarinowii Rhizoma-Curcumae Radix treating depression based on network pharmacology].

Fan WT, Wang Q.

Zhongguo Zhong Yao Za Zhi. 2018 Jun;43(12):2607-2611. doi: 10.19540/j.cnki.cjcmm.2018.0084. Chinese.

PMID:
29950083
15.

Anti-inflammatory effects of Polygala tenuifolia root through inhibition of NF-κB activation in lipopolysaccharide-induced BV2 microglial cells.

Cheong MH, Lee SR, Yoo HS, Jeong JW, Kim GY, Kim WJ, Jung IC, Choi YH.

J Ethnopharmacol. 2011 Oct 11;137(3):1402-8. doi: 10.1016/j.jep.2011.08.008. Epub 2011 Aug 10.

PMID:
21856398
16.

Bioactivity screening, extraction, and separation of lactate dehydrogenase inhibitors from Polygala tenuifolia Willd. based on a hyphenated strategy.

Li S, Liu S, Liu Z, Liu C, Song F, Pi Z.

J Sep Sci. 2017 Mar;40(6):1385-1395. doi: 10.1002/jssc.201601216. Epub 2017 Feb 22.

PMID:
28134488
17.

Stiripentol: A Novel Antiseizure Medication for the Management of Dravet Syndrome.

Buck ML, Goodkin HP.

Ann Pharmacother. 2019 Nov;53(11):1136-1144. doi: 10.1177/1060028019856008. Epub 2019 Jun 6.

PMID:
31167540
18.

Isolation and characterization of an oxidosqualene cyclase gene encoding a β-amyrin synthase involved in Polygala tenuifolia Willd. saponin biosynthesis.

Jin ML, Lee DY, Um Y, Lee JH, Park CG, Jetter R, Kim OT.

Plant Cell Rep. 2014 Mar;33(3):511-9. doi: 10.1007/s00299-013-1554-7. Epub 2014 Jan 14.

PMID:
24420413
19.

[Comparative Study on Quality of Volatile Oil of Acori Tatarinowii Rhizoma from Two Habitats].

Chen XL, Yuan DJ, Wu XR, Wu QD.

Zhong Yao Cai. 2015 Apr;38(4):770-3. Chinese.

PMID:
26672346
20.

Asarones from Acori Tatarinowii Rhizoma stimulate expression and secretion of neurotrophic factors in cultured astrocytes.

Lam KYC, Wu QY, Hu WH, Yao P, Wang HY, Dong TTX, Tsim KWK.

Neurosci Lett. 2019 Aug 10;707:134308. doi: 10.1016/j.neulet.2019.134308. Epub 2019 May 31.

PMID:
31153972

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