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Items: 1 to 20 of 92


Disruption of Robo2-Baiap2 integrated signaling drives cystic disease.

Li Q, Cui S, Ma Q, Liu Y, Yu H, Geng G, Agborbesong E, Ren C, Wei K, Zhang Y, Yang J, Bai X, Cai G, Xie Y, Li X, Chen X.

JCI Insight. 2019 Sep 19;4(18). pii: 127602. doi: 10.1172/jci.insight.127602.


Tulp3 Regulates Renal Cystogenesis by Trafficking of Cystoproteins to Cilia.

Hwang SH, Somatilaka BN, Badgandi H, Palicharla VR, Walker R, Shelton JM, Qian F, Mukhopadhyay S.

Curr Biol. 2019 Mar 4;29(5):790-802.e5. doi: 10.1016/j.cub.2019.01.047. Epub 2019 Feb 21.


Molecular basis of autosomal dominant polycystic kidney disease.

Al-Bhalal L, Akhtar M.

Adv Anat Pathol. 2005 May;12(3):126-33. Review.


Overexpression of Robo2 causes defects in the recruitment of metanephric mesenchymal cells and ureteric bud branching morphogenesis.

Ji J, Li Q, Xie Y, Zhang X, Cui S, Shi S, Chen X.

Biochem Biophys Res Commun. 2012 May 11;421(3):494-500. doi: 10.1016/j.bbrc.2012.04.029. Epub 2012 Apr 10.


The exocyst protein Sec10 is necessary for primary ciliogenesis and cystogenesis in vitro.

Zuo X, Guo W, Lipschutz JH.

Mol Biol Cell. 2009 May;20(10):2522-9. doi: 10.1091/mbc.E08-07-0772. Epub 2009 Mar 18.


Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome.

Cui C, Chatterjee B, Francis D, Yu Q, SanAgustin JT, Francis R, Tansey T, Henry C, Wang B, Lemley B, Pazour GJ, Lo CW.

Dis Model Mech. 2011 Jan;4(1):43-56. doi: 10.1242/dmm.006262. Epub 2010 Nov 2.


Diffuse expression of PAX2 and PAX8 in the cystic epithelium of mixed epithelial stromal tumor, angiomyolipoma with epithelial cysts, and primary renal synovial sarcoma: evidence supporting renal tubular differentiation.

Karafin M, Parwani AV, Netto GJ, Illei PB, Epstein JI, Ladanyi M, Argani P.

Am J Surg Pathol. 2011 Sep;35(9):1264-73. doi: 10.1097/PAS.0b013e31822539a1.


Toxic tubular injury in kidneys from Pkd1-deletion mice accelerates cystogenesis accompanied by dysregulated planar cell polarity and canonical Wnt signaling pathways.

Happé H, Leonhard WN, van der Wal A, van de Water B, Lantinga-van Leeuwen IS, Breuning MH, de Heer E, Peters DJ.

Hum Mol Genet. 2009 Jul 15;18(14):2532-42. doi: 10.1093/hmg/ddp190. Epub 2009 Apr 28.


Loss of primary cilia upregulates renal hypertrophic signaling and promotes cystogenesis.

Bell PD, Fitzgibbon W, Sas K, Stenbit AE, Amria M, Houston A, Reichert R, Gilley S, Siegal GP, Bissler J, Bilgen M, Chou PC, Guay-Woodford L, Yoder B, Haycraft CJ, Siroky B.

J Am Soc Nephrol. 2011 May;22(5):839-48. doi: 10.1681/ASN.2010050526. Epub 2011 Apr 14.


Polycystin-1 binds Par3/aPKC and controls convergent extension during renal tubular morphogenesis.

Castelli M, Boca M, Chiaravalli M, Ramalingam H, Rowe I, Distefano G, Carroll T, Boletta A.

Nat Commun. 2013;4:2658. doi: 10.1038/ncomms3658.


Shear Stress-Induced Alteration of Epithelial Organization in Human Renal Tubular Cells.

Maggiorani D, Dissard R, Belloy M, Saulnier-Blache JS, Casemayou A, Ducasse L, Grès S, Bellière J, Caubet C, Bascands JL, Schanstra JP, Buffin-Meyer B.

PLoS One. 2015 Jul 6;10(7):e0131416. doi: 10.1371/journal.pone.0131416. eCollection 2015.


Rho small G-protein-dependent binding of mDia to an Src homology 3 domain-containing IRSp53/BAIAP2.

Fujiwara T, Mammoto A, Kim Y, Takai Y.

Biochem Biophys Res Commun. 2000 May 19;271(3):626-9.


VIP17/MAL expression modulates epithelial cyst formation and ciliogenesis.

Takiar V, Mistry K, Carmosino M, Schaeren-Wiemers N, Caplan MJ.

Am J Physiol Cell Physiol. 2012 Oct 15;303(8):C862-71. doi: 10.1152/ajpcell.00338.2011. Epub 2012 Aug 15.


ROBO2 restricts the nephrogenic field and regulates Wolffian duct-nephrogenic cord separation.

Wainwright EN, Wilhelm D, Combes AN, Little MH, Koopman P.

Dev Biol. 2015 Aug 15;404(2):88-102. doi: 10.1016/j.ydbio.2015.05.023. Epub 2015 Jun 23.


Disruption of IFT complex A causes cystic kidneys without mitotic spindle misorientation.

Jonassen JA, SanAgustin J, Baker SP, Pazour GJ.

J Am Soc Nephrol. 2012 Apr;23(4):641-51. doi: 10.1681/ASN.2011080829. Epub 2012 Jan 26.


Novel insights into the role of the tumor suppressor von Hippel Lindau in cellular differentiation, ciliary biology, and cyst repression.

Wiesener MS, Maxwell PH, Eckardt KU.

J Mol Med (Berl). 2009 Sep;87(9):871-7. doi: 10.1007/s00109-009-0504-x. Epub 2009 Jul 24.


P53-Rb signaling pathway is involved in tubular cell senescence in renal ischemia/reperfusion injury.

Kailong L, Du X, Yani H, Lin Z, Jvrong Y, Ruihua S, Lin C.

Biocell. 2007 Aug;31(2):213-23.


Combined deletion of Vhl, Trp53 and Kif3a causes cystic and neoplastic renal lesions.

Guinot A, Lehmann H, Wild PJ, Frew IJ.

J Pathol. 2016 Jul;239(3):365-73. doi: 10.1002/path.4736. Epub 2016 May 30.


Plasticity of epithelial cells derived from human normal and ADPKD kidneys in primary cultures.

Elberg G, Guruswamy S, Logan CJ, Chen L, Turman MA.

Cell Tissue Res. 2008 Feb;331(2):495-508. Epub 2007 Nov 15.


The Joubert Syndrome Protein Inpp5e Controls Ciliogenesis by Regulating Phosphoinositides at the Apical Membrane.

Xu W, Jin M, Hu R, Wang H, Zhang F, Yuan S, Cao Y.

J Am Soc Nephrol. 2017 Jan;28(1):118-129. doi: 10.1681/ASN.2015080906. Epub 2016 Jul 8.

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