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Items: 1 to 20 of 99

1.

Development of a novel radioligand for imaging 18-kD translocator protein (TSPO) in a rat model of Parkinson's disease.

Wu CY, Chen YY, Lin JJ, Li JP, Chen JK, Hsieh TC, Kao CH.

BMC Med Imaging. 2019 Sep 18;19(1):78. doi: 10.1186/s12880-019-0375-8.

2.

Exploration of the impact of stereochemistry on the identification of the novel translocator protein PET imaging agent [(18)F]GE-180.

Chau WF, Black AM, Clarke A, Durrant C, Gausemel I, Khan I, Mantzilas D, Oulie I, Rogstad A, Trigg W, Jones PA.

Nucl Med Biol. 2015 Sep;42(9):711-9. doi: 10.1016/j.nucmedbio.2015.05.004. Epub 2015 May 27.

3.

DPA-714, a new translocator protein-specific ligand: synthesis, radiofluorination, and pharmacologic characterization.

James ML, Fulton RR, Vercoullie J, Henderson DJ, Garreau L, Chalon S, Dolle F, Costa B, Guilloteau D, Kassiou M.

J Nucl Med. 2008 May;49(5):814-22. doi: 10.2967/jnumed.107.046151. Epub 2008 Apr 15. Erratum in: J Nucl Med. 2008 Jul;49(7):1096. Selleri, Silvia [corrected to Costa, Barbara].

4.

The translocator protein ligand [¹⁸F]DPA-714 images glioma and activated microglia in vivo.

Winkeler A, Boisgard R, Awde AR, Dubois A, Thézé B, Zheng J, Ciobanu L, Dollé F, Viel T, Jacobs AH, Tavitian B.

Eur J Nucl Med Mol Imaging. 2012 May;39(5):811-23. doi: 10.1007/s00259-011-2041-4. Epub 2012 Jan 21.

5.

N-(6-[18F]Fluoro-4-phenoxypyridin-3-yl)-N-(2-methoxybenzyl)acetamide.

Chopra A.

Molecular Imaging and Contrast Agent Database (MICAD) [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2004-2013.
2013 Mar 26 [updated 2013 Apr 25].

6.

Synthesis of [¹¹C]PBR06 and [¹⁸F]PBR06 as agents for positron emission tomographic (PET) imaging of the translocator protein (TSPO).

Wang M, Gao M, Miller KD, Zheng QH.

Steroids. 2011 Nov;76(12):1331-40. doi: 10.1016/j.steroids.2011.06.012. Epub 2011 Jul 3.

PMID:
21756927
7.

Reactive astrocytes overexpress TSPO and are detected by TSPO positron emission tomography imaging.

Lavisse S, Guillermier M, Hérard AS, Petit F, Delahaye M, Van Camp N, Ben Haim L, Lebon V, Remy P, Dollé F, Delzescaux T, Bonvento G, Hantraye P, Escartin C.

J Neurosci. 2012 Aug 8;32(32):10809-18. doi: 10.1523/JNEUROSCI.1487-12.2012.

8.

Radiosynthesis and Preclinical Evaluation of [18F]F-DPA, A Novel Pyrazolo[1,5a]pyrimidine Acetamide TSPO Radioligand, in Healthy Sprague Dawley Rats.

Keller T, Krzyczmonik A, Forsback S, Picón FRL, Kirjavainen AK, Takkinen J, Rajander J, Cacheux F, Damont A, Dollé F, Rinne JO, Haaparanta-Solin M, Solin O.

Mol Imaging Biol. 2017 Oct;19(5):736-745. doi: 10.1007/s11307-016-1040-z.

9.

In Vivo Detection of Age- and Disease-Related Increases in Neuroinflammation by 18F-GE180 TSPO MicroPET Imaging in Wild-Type and Alzheimer's Transgenic Mice.

Liu B, Le KX, Park MA, Wang S, Belanger AP, Dubey S, Frost JL, Holton P, Reiser V, Jones PA, Trigg W, Di Carli MF, Lemere CA.

J Neurosci. 2015 Nov 25;35(47):15716-30. doi: 10.1523/JNEUROSCI.0996-15.2015.

10.

Detection of microglial activation in an acute model of neuroinflammation using PET and radiotracers 11C-(R)-PK11195 and 18F-GE-180.

Dickens AM, Vainio S, Marjamäki P, Johansson J, Lehtiniemi P, Rokka J, Rinne J, Solin O, Haaparanta-Solin M, Jones PA, Trigg W, Anthony DC, Airas L.

J Nucl Med. 2014 Mar;55(3):466-72. doi: 10.2967/jnumed.113.125625. Epub 2014 Feb 10.

11.

Characterization of a novel acetamidobenzoxazolone-based PET ligand for translocator protein (18 kDa) imaging of neuroinflammation in the brain.

Tiwari AK, Yui J, Fujinaga M, Kumata K, Shimoda Y, Yamasaki T, Xie L, Hatori A, Maeda J, Nengaki N, Zhang MR.

J Neurochem. 2014 May;129(4):712-20. doi: 10.1111/jnc.12670. Epub 2014 Feb 24.

12.

PET imaging of lung inflammation with [18F]FEDAC, a radioligand for translocator protein (18 kDa).

Hatori A, Yui J, Yamasaki T, Xie L, Kumata K, Fujinaga M, Yoshida Y, Ogawa M, Nengaki N, Kawamura K, Fukumura T, Zhang MR.

PLoS One. 2012;7(9):e45065. doi: 10.1371/journal.pone.0045065. Epub 2012 Sep 12.

13.

[18F]FEPPA a TSPO Radioligand: Optimized Radiosynthesis and Evaluation as a PET Radiotracer for Brain Inflammation in a Peripheral LPS-Injected Mouse Model.

Vignal N, Cisternino S, Rizzo-Padoin N, San C, Hontonnou F, Gelé T, Declèves X, Sarda-Mantel L, Hosten B.

Molecules. 2018 Jun 7;23(6). pii: E1375. doi: 10.3390/molecules23061375.

14.

[18F]DAA1106: Automated radiosynthesis using spirocyclic iodonium ylide and preclinical evaluation for positron emission tomography imaging of translocator protein (18 kDa).

Kumata K, Zhang Y, Fujinaga M, Ohkubo T, Mori W, Yamasaki T, Hanyu M, Xie L, Hatori A, Zhang MR.

Bioorg Med Chem. 2018 Sep 15;26(17):4817-4822. doi: 10.1016/j.bmc.2018.08.017. Epub 2018 Aug 12.

PMID:
30166255
15.

Visualization of acute liver damage induced by cycloheximide in rats using PET with [(18)F]FEDAC, a radiotracer for translocator protein (18 kDa).

Hatori A, Yui J, Xie L, Yamasaki T, Kumata K, Fujinaga M, Wakizaka H, Ogawa M, Nengaki N, Kawamura K, Zhang MR.

PLoS One. 2014 Jan 23;9(1):e86625. doi: 10.1371/journal.pone.0086625. eCollection 2014.

16.

Imaging microglial/macrophage activation in spinal cords of experimental autoimmune encephalomyelitis rats by positron emission tomography using the mitochondrial 18 kDa translocator protein radioligand [¹⁸F]DPA-714.

Abourbeh G, Thézé B, Maroy R, Dubois A, Brulon V, Fontyn Y, Dollé F, Tavitian B, Boisgard R.

J Neurosci. 2012 Apr 25;32(17):5728-36. doi: 10.1523/JNEUROSCI.2900-11.2012.

17.

Synthesis and evaluation of new (18)F-labelled acetamidobenzoxazolone-based radioligands for imaging of the translocator protein (18 kDa, TSPO) in the brain.

Tiwari AK, Fujinaga M, Yui J, Yamasaki T, Xie L, Kumata K, Mishra AK, Shimoda Y, Hatori A, Ji B, Ogawa M, Kawamura K, Wang F, Zhang MR.

Org Biomol Chem. 2014 Dec 21;12(47):9621-30. doi: 10.1039/c4ob01933d. Epub 2014 Oct 23.

PMID:
25339090
18.

PET imaging of [11C]PBR28 in Parkinson's disease patients does not indicate increased binding to TSPO despite reduced dopamine transporter binding.

Varnäs K, Cselényi Z, Jucaite A, Halldin C, Svenningsson P, Farde L, Varrone A.

Eur J Nucl Med Mol Imaging. 2019 Feb;46(2):367-375. doi: 10.1007/s00259-018-4161-6. Epub 2018 Oct 1.

19.

Synthesis of two novel [18F]fluorobenzene-containing radiotracers via spirocyclic iodonium ylides and positron emission tomography imaging of translocator protein (18 kDa) in ischemic brain.

Fujinaga M, Kumata K, Zhang Y, Hatori A, Yamasaki T, Mori W, Ohkubo T, Xie L, Nengaki N, Zhang MR.

Org Biomol Chem. 2018 Sep 26;16(37):8325-8335. doi: 10.1039/c8ob01700j.

PMID:
30206613
20.

A Novel PET Imaging Probe for the Detection and Monitoring of Translocator Protein 18 kDa Expression in Pathological Disorders.

Perrone M, Moon BS, Park HS, Laquintana V, Jung JH, Cutrignelli A, Lopedota A, Franco M, Kim SE, Lee BC, Denora N.

Sci Rep. 2016 Feb 8;6:20422. doi: 10.1038/srep20422.

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