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Effects of Helicobacter pylori treatment and vitamin and garlic supplementation on gastric cancer incidence and mortality: follow-up of a randomized intervention trial.

Li WQ, Zhang JY, Ma JL, Li ZX, Zhang L, Zhang Y, Guo Y, Zhou T, Li JY, Shen L, Liu WD, Han ZX, Blot WJ, Gail MH, Pan KF, You WC.

BMJ. 2019 Sep 11;366:l5016. doi: 10.1136/bmj.l5016.


Randomized double-blind factorial trial of three treatments to reduce the prevalence of precancerous gastric lesions.

You WC, Brown LM, Zhang L, Li JY, Jin ML, Chang YS, Ma JL, Pan KF, Liu WD, Hu Y, Crystal-Mansour S, Pee D, Blot WJ, Fraumeni JF Jr, Xu GW, Gail MH.

J Natl Cancer Inst. 2006 Jul 19;98(14):974-83.


Fifteen-year effects of Helicobacter pylori, garlic, and vitamin treatments on gastric cancer incidence and mortality.

Ma JL, Zhang L, Brown LM, Li JY, Shen L, Pan KF, Liu WD, Hu Y, Han ZX, Crystal-Mansour S, Pee D, Blot WJ, Fraumeni JF Jr, You WC, Gail MH.

J Natl Cancer Inst. 2012 Mar 21;104(6):488-92. doi: 10.1093/jnci/djs003. Epub 2012 Jan 23.


Helicobacter pylori eradication to prevent gastric cancer in a high-risk region of China: a randomized controlled trial.

Wong BC, Lam SK, Wong WM, Chen JS, Zheng TT, Feng RE, Lai KC, Hu WH, Yuen ST, Leung SY, Fong DY, Ho J, Ching CK, Chen JS; China Gastric Cancer Study Group.

JAMA. 2004 Jan 14;291(2):187-94.


Factorial trial of three interventions to reduce the progression of precancerous gastric lesions in Shandong, China: design issues and initial data.

Gail MH, You WC, Chang YS, Zhang L, Blot WJ, Brown LM, Groves FD, Heinrich JP, Hu J, Jin ML, Li JY, Liu WD, Ma JL, Mark SD, Rabkin CS, Fraumeni JF Jr, Xu GW.

Control Clin Trials. 1998 Aug;19(4):352-69.


A factorial trial including garlic supplements assesses effect in reducing precancerous gastric lesions.

Gail MH, You WC.

J Nutr. 2006 Mar;136(3 Suppl):813S-815S. doi: 10.1093/jn/136.3.813S.


Long-term garlic or micronutrient supplementation, but not anti-Helicobacter pylori therapy, increases serum folate or glutathione without affecting serum vitamin B-12 or homocysteine in a rural Chinese population.

Wang Y, Zhang L, Moslehi R, Ma J, Pan K, Zhou T, Liu W, Brown LM, Hu Y, Pee D, Gail MH, You W.

J Nutr. 2009 Jan;139(1):106-12. doi: 10.3945/jn.108.091389. Epub 2008 Dec 3.


Chemoprevention of precancerous gastric lesions with antioxidant vitamin supplementation: a randomized trial in a high-risk population.

Plummer M, Vivas J, Lopez G, Bravo JC, Peraza S, Carillo E, Cano E, Castro D, Andrade O, Sánchez V, Garcia R, Buiatti E, Aebischer C, Franceschi S, Oliver W, Muñoz N.

J Natl Cancer Inst. 2007 Jan 17;99(2):137-46.


Helicobacter pylori infection, garlic intake and precancerous lesions in a Chinese population at low risk of gastric cancer.

You WC, Zhang L, Gail MH, Ma JL, Chang YS, Blot WJ, Li JY, Zhao CL, Liu WD, Li HQ, Hu YR, Bravo JC, Correa P, Xu GW, Fraumeni JF Jr.

Int J Epidemiol. 1998 Dec;27(6):941-4.


An intervention trial to inhibit the progression of precancerous gastric lesions: compliance, serum micronutrients and S-allyl cysteine levels, and toxicity.

You WC, Chang YS, Heinrich J, Ma JL, Liu WD, Zhang L, Brown LM, Yang CS, Gail MH, Fraumeni JF Jr, Xu GW.

Eur J Cancer Prev. 2001 Jun;10(3):257-63.


Effects of selective COX-2 inhibitor and Helicobacter pylori eradication on precancerous gastric lesions.

Wong BC, Zhang L, Ma JL, Pan KF, Li JY, Shen L, Liu WD, Feng GS, Zhang XD, Li J, Lu AP, Xia HH, Lam S, You WC.

Gut. 2012 Jun;61(6):812-8. doi: 10.1136/gutjnl-2011-300154. Epub 2011 Sep 13.


Effects of Helicobacter pylori treatment on gastric cancer incidence and mortality in subgroups.

Li WQ, Ma JL, Zhang L, Brown LM, Li JY, Shen L, Pan KF, Liu WD, Hu Y, Han ZX, Crystal-Mansour S, Pee D, Blot WJ, Fraumeni JF Jr, You WC, Gail MH.

J Natl Cancer Inst. 2014 Jun 12;106(7). pii: dju116. doi: 10.1093/jnci/dju116. Print 2014 Jul.


[Helicobacter pylori and the progression of gastric cancer: a 10-year cohort study].

Ma JL, Zhang L, Pan KF, Liu WD, Feng GS, You WC.

Zhonghua Yi Xue Za Zhi. 2005 Oct 19;85(39):2758-61. Chinese.


Helicobacter pylori Therapy for the Prevention of Metachronous Gastric Cancer.

Choi IJ, Kook MC, Kim YI, Cho SJ, Lee JY, Kim CG, Park B, Nam BH.

N Engl J Med. 2018 Mar 22;378(12):1085-1095. doi: 10.1056/NEJMoa1708423.


Helicobacter pylori eradication for the prevention of gastric neoplasia.

Ford AC, Forman D, Hunt R, Yuan Y, Moayyedi P.

Cochrane Database Syst Rev. 2015 Jul 22;(7):CD005583. doi: 10.1002/14651858.CD005583.pub2. Review.


Helicobacter pylori infection and development of gastric cancer in Korea: long-term follow-up.

Kim N, Park RY, Cho SI, Lim SH, Lee KH, Lee W, Kang HM, Lee HS, Jung HC, Song IS.

J Clin Gastroenterol. 2008 May-Jun;42(5):448-54. doi: 10.1097/MCG.0b013e318046eac3.


Effects of vitamin/mineral supplementation on the prevalence of histological dysplasia and early cancer of the esophagus and stomach: results from the General Population Trial in Linxian, China.

Wang GQ, Dawsey SM, Li JY, Taylor PR, Li B, Blot WJ, Weinstein WM, Liu FS, Lewin KJ, Wang H, et al.

Cancer Epidemiol Biomarkers Prev. 1994 Mar;3(2):161-6.


Chemoprevention of gastric dysplasia: randomized trial of antioxidant supplements and anti-helicobacter pylori therapy.

Correa P, Fontham ET, Bravo JC, Bravo LE, Ruiz B, Zarama G, Realpe JL, Malcom GT, Li D, Johnson WD, Mera R.

J Natl Cancer Inst. 2000 Dec 6;92(23):1881-8.


Association Between Helicobacter pylori Eradication and Gastric Cancer Incidence: A Systematic Review and Meta-analysis.

Lee YC, Chiang TH, Chou CK, Tu YK, Liao WC, Wu MS, Graham DY.

Gastroenterology. 2016 May;150(5):1113-1124.e5. doi: 10.1053/j.gastro.2016.01.028. Epub 2016 Feb 2. Review.

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