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Items: 1 to 20 of 100

1.

Vactosertib, a Novel, Orally Bioavailable Activin Receptor-Like Kinase 5 Inhibitor, Promotes Regression of Fibrotic Plaques in a Rat Model of Peyronie's Disease.

Song KM, Chung DY, Choi MJ, Ghatak K, Nguyen NM, Limanjaya A, Kwon MH, Ock J, Yin GN, Kim DK, Ryu JK, Suh JK.

World J Mens Health. 2019 Aug 27. doi: 10.5534/wjmh.190071. [Epub ahead of print]

2.

Transforming growth factor (TGF)-β type I receptor kinase (ALK5) inhibitor alleviates profibrotic TGF-β1 responses in fibroblasts derived from Peyronie's plaque.

Piao S, Choi MJ, Tumurbaatar M, Kim WJ, Jin HR, Shin SH, Tuvshintur B, Yin GN, Song JS, Kwon MH, Lee SJ, Han JY, Kim SJ, Ryu JK, Suh JK.

J Sex Med. 2010 Oct;7(10):3385-95. doi: 10.1111/j.1743-6109.2010.01753.x.

PMID:
20233292
3.

IN-1130, a novel transforming growth factor-beta type I receptor kinase (activin receptor-like kinase 5) inhibitor, promotes regression of fibrotic plaque and corrects penile curvature in a rat model of Peyronie's disease.

Ryu JK, Piao S, Shin HY, Choi MJ, Zhang LW, Jin HR, Kim WJ, Han JY, Hong SS, Park SH, Lee SJ, Kim IH, Lee CR, Kim DK, Mamura M, Kim SJ, Suh JK.

J Sex Med. 2009 May;6(5):1284-96. doi: 10.1111/j.1743-6109.2009.01216.x. Epub 2009 Mar 18.

PMID:
19473283
4.

Silencing histone deacetylase 2 using small hairpin RNA induces regression of fibrotic plaque in a rat model of Peyronie's disease.

Kwon KD, Choi MJ, Park JM, Song KM, Kwon MH, Batbold D, Yin GN, Kim WJ, Ryu JK, Suh JK.

BJU Int. 2014 Dec;114(6):926-36. doi: 10.1111/bju.12812. Epub 2014 Aug 13.

5.

Reduction in Peyronie's-like plaque size using a vacuum erection device in a rat model of Peyronie's disease via the TGF-β/SMAD signalling pathway.

Li J, Wang S, Qin F, Zhu M, You X, Wu C, Fu F, Yuan J.

Andrologia. 2018 Sep;50(7):e13051. doi: 10.1111/and.13051. Epub 2018 May 28.

PMID:
29806152
6.

Activin Receptor-Like Kinase 5 Inhibitor Attenuates Fibrosis in Fibroblasts Derived from Peyronie's Plaque.

Jang JH, Ryu JK, Suh JK.

Korean J Urol. 2012 Jan;53(1):44-9. doi: 10.4111/kju.2012.53.1.44. Epub 2012 Jan 25.

7.

Fibrin as an inducer of fibrosis in the tunica albuginea of the rat: a new animal model of Peyronie's disease.

Davila HH, Ferrini MG, Rajfer J, Gonzalez-Cadavid NF.

BJU Int. 2003 Jun;91(9):830-8.

8.

Alterations in the transforming growth factor (TGF)-beta pathway as a potential factor in the pathogenesis of Peyronie's disease.

Haag SM, Hauck EW, Szardening-Kirchner C, Diemer T, Cha ES, Weidner W, Eickelberg O.

Eur Urol. 2007 Jan;51(1):255-61. Epub 2006 May 19.

PMID:
16782264
9.

Inhibition of histone deacetylase 2 mitigates profibrotic TGF-β1 responses in fibroblasts derived from Peyronie's plaque.

Ryu JK, Kim WJ, Choi MJ, Park JM, Song KM, Kwon MH, Das ND, Kwon KD, Batbold D, Yin GN, Suh JK.

Asian J Androl. 2013 Sep;15(5):640-5. doi: 10.1038/aja.2013.61. Epub 2013 Jun 17.

10.

Adipose tissue-derived stem cell therapy for prevention and treatment of erectile dysfunction in a rat model of Peyronie's disease.

Gokce A, Abd Elmageed ZY, Lasker GF, Bouljihad M, Kim H, Trost LW, Kadowitz PJ, Abdel-Mageed AB, Sikka SC, Hellstrom WJ.

Andrology. 2014 Mar;2(2):244-51. doi: 10.1111/j.2047-2927.2013.00181.x.

11.

Silencing Histone Deacetylase 7 Alleviates Transforming Growth Factor-β1-Induced Profibrotic Responses in Fibroblasts Derived from Peyronie's Plaque.

Kang DH, Yin GN, Choi MJ, Song KM, Ghatak K, Minh NN, Kwon MH, Seong DH, Ryu JK, Suh JK.

World J Mens Health. 2018 May;36(2):139-146. doi: 10.5534/wjmh.170005.

12.

Intratunical Injection of Genetically Modified Adipose Tissue-Derived Stem Cells with Human Interferon α-2b for Treatment of Erectile Dysfunction in a Rat Model of Tunica Albugineal Fibrosis.

Gokce A, Abd Elmageed ZY, Lasker GF, Bouljihad M, Braun SE, Kim H, Kadowitz PJ, Abdel-Mageed AB, Sikka SC, Hellstrom WJ.

J Sex Med. 2015 Jul;12(7):1533-44. doi: 10.1111/jsm.12916. Epub 2015 Jun 10.

13.

A novel PI3K inhibitor alleviates fibrotic responses in fibroblasts derived from Peyronie's plaques.

Jung KH, Ryu YL, Lee HS, Lee H, Son MK, Yan HH, Hong SW, Ryu JK, Hong S, Suh JK, Hong SS.

Int J Oncol. 2013 Jun;42(6):2001-8. doi: 10.3892/ijo.2013.1905. Epub 2013 Apr 16.

PMID:
23588860
14.

Effect of SMAD7 gene overexpression on TGF-β1-induced profibrotic responses in fibroblasts derived from Peyronie's plaque.

Choi MJ, Song KM, Park JM, Kwon MH, Kwon KD, Park SH, Ryu DS, Ryu JK, Suh JK.

Asian J Androl. 2015 May-Jun;17(3):487-92. doi: 10.4103/1008-682X.142130.

15.

Understanding the Role of Adenosine Receptors in the Myofibroblast Transformation in Peyronie's Disease.

Mateus M, Ilg MM, Stebbeds WJ, Christopher N, Muneer A, Ralph DJ, Cellek S.

J Sex Med. 2018 Jul;15(7):947-957. doi: 10.1016/j.jsxm.2018.05.003. Epub 2018 Jun 8.

PMID:
29891411
16.

Effects of long-term vardenafil treatment on the development of fibrotic plaques in a rat model of Peyronie's disease.

Ferrini MG, Kovanecz I, Nolazco G, Rajfer J, Gonzalez-Cadavid NF.

BJU Int. 2006 Mar;97(3):625-33.

17.

Antifibrotic Synergy Between Phosphodiesterase Type 5 Inhibitors and Selective Oestrogen Receptor Modulators in Peyronie's Disease Models.

Ilg MM, Mateus M, Stebbeds WJ, Milenkovic U, Christopher N, Muneer A, Albersen M, Ralph DJ, Cellek S.

Eur Urol. 2019 Feb;75(2):329-340. doi: 10.1016/j.eururo.2018.10.014. Epub 2018 Oct 19.

18.

Intratunical injection of human adipose tissue-derived stem cells prevents fibrosis and is associated with improved erectile function in a rat model of Peyronie's disease.

Castiglione F, Hedlund P, Van der Aa F, Bivalacqua TJ, Rigatti P, Van Poppel H, Montorsi F, De Ridder D, Albersen M.

Eur Urol. 2013 Mar;63(3):551-60. doi: 10.1016/j.eururo.2012.09.034. Epub 2012 Sep 24. Erratum in: Eur Urol. 2013 Jul;64(1):e21.

19.

Simvastatin and the Rho-kinase inhibitor Y-27632 prevent myofibroblast transformation in Peyronie's disease-derived fibroblasts via inhibition of YAP/TAZ nuclear translocation.

Milenkovic U, Ilg MM, Zuccato C, Ramazani Y, De Ridder D, Albersen M.

BJU Int. 2019 Apr;123(4):703-715. doi: 10.1111/bju.14638. Epub 2019 Jan 6.

PMID:
30536599
20.

The effect of surgical trauma on rat tunica albuginea.

El-Sakka AI, Selph CA, Yen TS, Dahiya R, Lue TF.

J Urol. 1998 May;159(5):1700-7.

PMID:
9554397

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