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Next-generation unnatural monosaccharides reveal that ESRRB O-GlcNAcylation regulates pluripotency of mouse embryonic stem cells.

Hao Y, Fan X, Shi Y, Zhang C, Sun DE, Qin K, Qin W, Zhou W, Chen X.

Nat Commun. 2019 Sep 6;10(1):4065. doi: 10.1038/s41467-019-11942-y.


Artificial Cysteine S-Glycosylation Induced by Per-O-Acetylated Unnatural Monosaccharides during Metabolic Glycan Labeling.

Qin W, Qin K, Fan X, Peng L, Hong W, Zhu Y, Lv P, Du Y, Huang R, Han M, Cheng B, Liu Y, Zhou W, Wang C, Chen X.

Angew Chem Int Ed Engl. 2018 Feb 12;57(7):1817-1820. doi: 10.1002/anie.201711710. Epub 2018 Jan 5.


O-GlcNAc regulates pluripotency and reprogramming by directly acting on core components of the pluripotency network.

Jang H, Kim TW, Yoon S, Choi SY, Kang TW, Kim SY, Kwon YW, Cho EJ, Youn HD.

Cell Stem Cell. 2012 Jul 6;11(1):62-74. doi: 10.1016/j.stem.2012.03.001. Epub 2012 May 17.


Esrrb activates Oct4 transcription and sustains self-renewal and pluripotency in embryonic stem cells.

Zhang X, Zhang J, Wang T, Esteban MA, Pei D.

J Biol Chem. 2008 Dec 19;283(51):35825-33. doi: 10.1074/jbc.M803481200. Epub 2008 Oct 28.


RING1B O-GlcNAcylation regulates gene targeting of polycomb repressive complex 1 in human embryonic stem cells.

Maury JJ, El Farran CA, Ng D, Loh YH, Bi X, Bardor M, Choo AB.

Stem Cell Res. 2015 Jul;15(1):182-9. doi: 10.1016/j.scr.2015.06.007. Epub 2015 Jun 17.


Gas5 is an essential lncRNA regulator for self-renewal and pluripotency of mouse embryonic stem cells and induced pluripotent stem cells.

Tu J, Tian G, Cheung HH, Wei W, Lee TL.

Stem Cell Res Ther. 2018 Mar 21;9(1):71. doi: 10.1186/s13287-018-0813-5.


SOX2 O-GlcNAcylation alters its protein-protein interactions and genomic occupancy to modulate gene expression in pluripotent cells.

Myers SA, Peddada S, Chatterjee N, Friedrich T, Tomoda K, Krings G, Thomas S, Maynard J, Broeker M, Thomson M, Pollard K, Yamanaka S, Burlingame AL, Panning B.

Elife. 2016 Mar 7;5:e10647. doi: 10.7554/eLife.10647.


Adequate concentration of B cell leukemia/lymphoma 3 (Bcl3) is required for pluripotency and self-renewal of mouse embryonic stem cells via downregulation of Nanog transcription.

Kang S, Yun J, Kim DY, Jung SY, Kim YJ, Park JH, Ji ST, Jang WB, Ha J, Kim JH, Baek SH, Kwon SM.

BMB Rep. 2018 Feb;51(2):92-97.


Estrogen-related receptor beta interacts with Oct4 to positively regulate Nanog gene expression.

van den Berg DL, Zhang W, Yates A, Engelen E, Takacs K, Bezstarosti K, Demmers J, Chambers I, Poot RA.

Mol Cell Biol. 2008 Oct;28(19):5986-95. doi: 10.1128/MCB.00301-08. Epub 2008 Jul 28.


LIF-activated Jak signaling determines Esrrb expression during late-stage reprogramming.

Huang D, Wang L, Duan J, Huang C, Tian XC, Zhang M, Tang Y.

Biol Open. 2018 Jan 22;7(1). pii: bio029264. doi: 10.1242/bio.029264.


Elevated O-GlcNAc levels activate epigenetically repressed genes and delay mouse ESC differentiation without affecting naïve to primed cell transition.

Speakman CM, Domke TC, Wongpaiboonwattana W, Sanders K, Mudaliar M, van Aalten DM, Barton GJ, Stavridis MP.

Stem Cells. 2014 Oct;32(10):2605-15. doi: 10.1002/stem.1761.


Metabolic Chemical Reporters of Glycans Exhibit Cell-Type-Selective Metabolism and Glycoprotein Labeling.

Batt AR, Zaro BW, Navarro MX, Pratt MR.

Chembiochem. 2017 Jul 4;18(13):1177-1182. doi: 10.1002/cbic.201700020. Epub 2017 Mar 28.


Metabolic cross-talk allows labeling of O-linked beta-N-acetylglucosamine-modified proteins via the N-acetylgalactosamine salvage pathway.

Boyce M, Carrico IS, Ganguli AS, Yu SH, Hangauer MJ, Hubbard SC, Kohler JJ, Bertozzi CR.

Proc Natl Acad Sci U S A. 2011 Feb 22;108(8):3141-6. doi: 10.1073/pnas.1010045108. Epub 2011 Feb 7.


Icaritin enhances mESC self-renewal through upregulating core pluripotency transcription factors mediated by ERα.

Tsang WP, Zhang F, He Q, Cai W, Huang J, Chan WY, Shen Z, Wan C.

Sci Rep. 2017 Jan 16;7:40894. doi: 10.1038/srep40894.


Conserved long noncoding RNAs transcriptionally regulated by Oct4 and Nanog modulate pluripotency in mouse embryonic stem cells.

Sheik Mohamed J, Gaughwin PM, Lim B, Robson P, Lipovich L.

RNA. 2010 Feb;16(2):324-37. doi: 10.1261/rna.1441510. Epub 2009 Dec 21.


The long non-coding RNA Snhg3 is essential for mouse embryonic stem cell self-renewal and pluripotency.

Lu W, Yu J, Shi F, Zhang J, Huang R, Yin S, Songyang Z, Huang J.

Stem Cell Res Ther. 2019 May 31;10(1):157. doi: 10.1186/s13287-019-1270-5.


ESRRB plays a crucial role in the promotion of porcine cell reprograming.

Yang F, Ren Y, Li H, Wang H.

J Cell Physiol. 2018 Feb;233(2):1601-1611. doi: 10.1002/jcp.26063. Epub 2017 Jul 31.


O-GlcNAc transferase regulates transcriptional activity of human Oct4.

Constable S, Lim JM, Vaidyanathan K, Wells L.

Glycobiology. 2017 Oct 1;27(10):927-937. doi: 10.1093/glycob/cwx055.

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