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Expression and clinical significance of CPS1 in glioblastoma multiforme.

Wu G, Yan Y, Zhou Y, Wang X, Wei J, Chen X, Lin W, Ou C, Zhou J, Xu Z.

Curr Res Transl Med. 2019 Sep 3. pii: S2452-3186(19)30032-7. doi: 10.1016/j.retram.2019.08.003. [Epub ahead of print]


DNA methylation suppresses expression of the urea cycle enzyme carbamoyl phosphate synthetase 1 (CPS1) in human hepatocellular carcinoma.

Liu H, Dong H, Robertson K, Liu C.

Am J Pathol. 2011 Feb;178(2):652-61. doi: 10.1016/j.ajpath.2010.10.023.


LIM and SH3 protein 1 regulates cell growth and chemosensitivity of human glioblastoma via the PI3K/AKT pathway.

Zhong C, Chen Y, Tao B, Peng L, Peng T, Yang X, Xia X, Chen L.

BMC Cancer. 2018 Jul 6;18(1):722. doi: 10.1186/s12885-018-4649-2.


Identification of aberrantly methylated differentially expressed genes in glioblastoma multiforme and their association with patient survival.

Zhang M, Lv X, Jiang Y, Li G, Qiao Q.

Exp Ther Med. 2019 Sep;18(3):2140-2152. doi: 10.3892/etm.2019.7807. Epub 2019 Jul 24.


The activity of the carbamoyl phosphate synthase 1 promoter in human liver-derived cells is dependent on hepatocyte nuclear factor 3-beta.

Chen Z, Tang N, Wang X, Chen Y.

J Cell Mol Med. 2017 Sep;21(9):2036-2045. doi: 10.1111/jcmm.13123. Epub 2017 Mar 8.


Ammonia-lowering activities and carbamoyl phosphate synthetase 1 (Cps1) induction mechanism of a natural flavonoid.

Nohara K, Shin Y, Park N, Jeong K, He B, Koike N, Yoo SH, Chen Z.

Nutr Metab (Lond). 2015 Jun 9;12:23. doi: 10.1186/s12986-015-0020-7. eCollection 2015.


Fatal hyperammonemia and carbamoyl phosphate synthetase 1 (CPS1) deficiency following high-dose chemotherapy and autologous hematopoietic stem cell transplantation.

Laemmle A, Hahn D, Hu L, Rüfenacht V, Gautschi M, Leibundgut K, Nuoffer JM, Häberle J.

Mol Genet Metab. 2015 Mar;114(3):438-44. doi: 10.1016/j.ymgme.2015.01.002. Epub 2015 Jan 24.


Identification of a multidimensional transcriptome signature for survival prediction of postoperative glioblastoma multiforme patients.

Gao WZ, Guo LM, Xu TQ, Yin YH, Jia F.

J Transl Med. 2018 Dec 20;16(1):368. doi: 10.1186/s12967-018-1744-8.


Network Analysis of Metabolite GWAS Hits: Implication of CPS1 and the Urea Cycle in Weight Maintenance.

Matone A, Scott-Boyer MP, Carayol J, Fazelzadeh P, Lefebvre G, Valsesia A, Charon C, Vervoort J, Astrup A, Saris WH, Morine M, Hager J.

PLoS One. 2016 Mar 3;11(3):e0150495. doi: 10.1371/journal.pone.0150495. eCollection 2016.


Molecular characterization of carbamoyl-phosphate synthetase (CPS1) deficiency using human recombinant CPS1 as a key tool.

Diez-Fernandez C, Martínez AI, Pekkala S, Barcelona B, Pérez-Arellano I, Guadalajara AM, Summar M, Cervera J, Rubio V.

Hum Mutat. 2013 Aug;34(8):1149-59. doi: 10.1002/humu.22349. Epub 2013 May 28. Erratum in: Hum Mutat. 2019 Mar;40(3):355-356.


Understanding carbamoyl phosphate synthetase (CPS1) deficiency by using the recombinantly purified human enzyme: effects of CPS1 mutations that concentrate in a central domain of unknown function.

Díez-Fernández C, Hu L, Cervera J, Häberle J, Rubio V.

Mol Genet Metab. 2014 Jun;112(2):123-32. doi: 10.1016/j.ymgme.2014.04.003. Epub 2014 Apr 18.


Role of CPS1 in Cell Growth, Metabolism and Prognosis in LKB1-Inactivated Lung Adenocarcinoma.

Çeliktas M, Tanaka I, Tripathi SC, Fahrmann JF, Aguilar-Bonavides C, Villalobos P, Delgado O, Dhillon D, Dennison JB, Ostrin EJ, Wang H, Behrens C, Do KA, Gazdar AF, Hanash SM, Taguchi A.

J Natl Cancer Inst. 2017 Mar 1;109(3):1-9. doi: 10.1093/jnci/djw231.


Construction of Potential Glioblastoma Multiforme-Related miRNA-mRNA Regulatory Network.

Lou W, Ding B, Xu L, Fan W.

Front Mol Neurosci. 2019 Mar 26;12:66. doi: 10.3389/fnmol.2019.00066. eCollection 2019.


In search of druggable targets for GBM amino acid metabolism.

Panosyan EH, Lin HJ, Koster J, Lasky JL 3rd.

BMC Cancer. 2017 Feb 28;17(1):162. doi: 10.1186/s12885-017-3148-1.


Genetic, structural and biochemical basis of carbamoyl phosphate synthetase 1 deficiency.

Martínez AI, Pérez-Arellano I, Pekkala S, Barcelona B, Cervera J.

Mol Genet Metab. 2010 Dec;101(4):311-23. doi: 10.1016/j.ymgme.2010.08.002. Epub 2010 Aug 6. Review.


Gene expression profiling reveals Ki-67 associated proliferation signature in human glioblastoma.

Jin Q, Zhang W, Qiu XG, Yan W, You G, Liu YW, Jiang T, Wang L.

Chin Med J (Engl). 2011 Sep;124(17):2584-8.


[Experimental studies on correlation between nucleolus spindle-related protein 1 and the malignant progression and prognosis of human glioblastoma multiforme].

Xue YP, Ji XY, Yang L, Liu HR, Sheng YJ, Dai XX, Xi YJ, Liu JC, Shi J, Xie T, Zhang YS, Ma JW, Dong J.

Zhonghua Yi Xue Za Zhi. 2018 Jan 30;98(5):340-345. doi: 10.3760/cma.j.issn.0376-2491.2018.05.005. Chinese.


Expression Profile Analysis Identifies a Novel Five-Gene Signature to Improve Prognosis Prediction of Glioblastoma.

Yin W, Tang G, Zhou Q, Cao Y, Li H, Fu X, Wu Z, Jiang X.

Front Genet. 2019 May 3;10:419. doi: 10.3389/fgene.2019.00419. eCollection 2019.

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