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Analysis of Tumor Genomic Pathway Alterations Using Broad-Panel Next-Generation Sequencing in Surgically Resected Lung Adenocarcinoma.

Zhou J, Sanchez-Vega F, Caso R, Tan KS, Brandt WS, Jones GD, Yan S, Adusumilli PS, Bott M, Huang J, Isbell JM, Sihag S, Molena D, Rusch VW, Chatila WK, Rekhtman N, Yang F, Ladanyi M, Solit DB, Berger MF, Schultz N, Jones DR.

Clin Cancer Res. 2019 Aug 27. doi: 10.1158/1078-0432.CCR-19-1651. [Epub ahead of print]


BRMS1 Expression in Surgically Resected Lung Adenocarcinoma Predicts Future Metastases and Is Associated with a Poor Prognosis.

Bucciarelli PR, Tan KS, Chudgar NP, Brandt W, Montecalvo J, Eguchi T, Liu Y, Aly R, Travis WD, Adusumilli PS, Jones DR.

J Thorac Oncol. 2018 Jan;13(1):73-84. doi: 10.1016/j.jtho.2017.10.006. Epub 2017 Oct 31. Erratum in: J Thorac Oncol. 2019 Jun;14(6):1109.


Association of Alterations in Main Driver Genes With Outcomes of Patients With Resected Pancreatic Ductal Adenocarcinoma.

Qian ZR, Rubinson DA, Nowak JA, Morales-Oyarvide V, Dunne RF, Kozak MM, Welch MW, Brais LK, Da Silva A, Li T, Li W, Masuda A, Yang J, Shi Y, Gu M, Masugi Y, Bui J, Zellers CL, Yuan C, Babic A, Khalaf N, Aguirre A, Ng K, Miksad RA, Bullock AJ, Chang DT, Tseng JF, Clancy TE, Linehan DC, Findeis-Hosey JJ, Doyle LA, Thorner AR, Ducar M, Wollison B, Laing A, Hahn WC, Meyerson M, Fuchs CS, Ogino S, Hornick JL, Hezel AF, Koong AC, Wolpin BM.

JAMA Oncol. 2018 Mar 8;4(3):e173420. doi: 10.1001/jamaoncol.2017.3420. Epub 2018 Mar 8.


Broad, Hybrid Capture-Based Next-Generation Sequencing Identifies Actionable Genomic Alterations in Lung Adenocarcinomas Otherwise Negative for Such Alterations by Other Genomic Testing Approaches.

Drilon A, Wang L, Arcila ME, Balasubramanian S, Greenbowe JR, Ross JS, Stephens P, Lipson D, Miller VA, Kris MG, Ladanyi M, Rizvi NA.

Clin Cancer Res. 2015 Aug 15;21(16):3631-9. doi: 10.1158/1078-0432.CCR-14-2683. Epub 2015 Jan 7.


Visceral Pleural Invasion Is a Significant Prognostic Factor in Patients with Partly Solid Lung Adenocarcinoma Sized 30 mm or Smaller.

Seok Y, Lee E.

Thorac Cardiovasc Surg. 2018 Mar;66(2):150-155. doi: 10.1055/s-0036-1586757. Epub 2016 Aug 12.


Prognostic factors in curatively resected pathological stage I lung adenocarcinoma.

Yang Y, Mao Y, Yang L, He J, Gao S, Mu J, Xue Q, Wang D, Zhao J, Gao Y, Zhang Z, Ding N, Yang D.

J Thorac Dis. 2017 Dec;9(12):5267-5277. doi: 10.21037/jtd.2017.11.65.


The expression of plakoglobin is a potential prognostic biomarker for patients with surgically resected lung adenocarcinoma.

He X, Zhou T, Yang G, Fang W, Li Z, Zhan J, Zhao Y, Cheng Z, Huang Y, Zhao H, Zhang L.

Oncotarget. 2016 Mar 22;7(12):15274-87. doi: 10.18632/oncotarget.7729.


Clinicopathologic and prognostic significance of c-MYC copy number gain in lung adenocarcinomas.

Seo AN, Yang JM, Kim H, Jheon S, Kim K, Lee CT, Jin Y, Yun S, Chung JH, Paik JH.

Br J Cancer. 2014 May 27;110(11):2688-99. doi: 10.1038/bjc.2014.218. Epub 2014 May 8.


Visceral pleural invasion predict a poor survival among lung adenocarcinoma patients with tumor size ≤ 3cm.

Chen T, Luo J, Wang R, Gu H, Gu Y, Huang Q, Wang Y, Zheng J, Gu C, Pan X, Yang J, Yang Y, Zhao H.

Oncotarget. 2017 Mar 22;8(39):66576-66583. doi: 10.18632/oncotarget.16476. eCollection 2017 Sep 12.


The prognostic effect of single and multiple cancer-related somatic mutations in resected non-small-cell lung cancer.

Jao K, Tomasini P, Kamel-Reid S, Korpanty GJ, Mascaux C, Sakashita S, Labbé C, Leighl NB, Liu G, Feld R, Bradbury PA, Hwang DM, Pintilie M, Tsao MS, Shepherd FA.

Lung Cancer. 2018 Sep;123:22-29. doi: 10.1016/j.lungcan.2018.06.023. Epub 2018 Jun 19.


Comprehensive Molecular Characterization of Young Chinese Patients with Lung Adenocarcinoma Identified a Distinctive Genetic Profile.

Hou H, Zhu H, Zhao H, Yan W, Wang Y, Jiang M, Liu B, Liu D, Zhou N, Zhang C, Li P, Chang L, Guan Y, Wang Z, Zhang X, Li Z, Fang B, Zhang X.

Oncologist. 2018 Sep;23(9):1008-1015. doi: 10.1634/theoncologist.2017-0629. Epub 2018 Apr 26.


Anaplastic lymphoma kinase rearrangement in surgically resected stage IA lung adenocarcinoma.

Shin SH, Lee H, Jeong BH, Choi YS, Shin MH, Kim S, Han J, Lee KS, Shim YM, Kwon OJ, Kim H.

J Thorac Dis. 2018 Jun;10(6):3460-3467. doi: 10.21037/jtd.2018.05.131.


Prognostic factors including lymphovascular invasion on survival for resected non-small cell lung cancer.

Okiror L, Harling L, Toufektzian L, King J, Routledge T, Harrison-Phipps K, Pilling J, Veres L, Lal R, Bille A.

J Thorac Cardiovasc Surg. 2018 Aug;156(2):785-793. doi: 10.1016/j.jtcvs.2018.02.108. Epub 2018 Apr 12.


Positive intraoperative pleural lavage cytology is a predictive marker of disease recurrence in stage I lung adenocarcinoma.

Yanagawa N, Shiono S, Abiko M, Abe M, Watanabe K, Watanabe I, Uematsu M, Ogata SY, Sato T, Tamura G.

Interact Cardiovasc Thorac Surg. 2014 May;18(5):621-5. doi: 10.1093/icvts/ivu015. Epub 2014 Feb 13.


Solitary pulmonary nodular lung adenocarcinoma: correlation of histopathologic scoring and patient survival with imaging biomarkers.

Lee HY, Jeong JY, Lee KS, Kim HJ, Han J, Kim BT, Kim J, Shim YM, Kim JH, Song I.

Radiology. 2012 Sep;264(3):884-93. doi: 10.1148/radiol.12111793. Epub 2012 Jul 24.


Prediction of pathologic node-negative clinical stage IA lung adenocarcinoma for optimal candidates undergoing sublobar resection.

Tsutani Y, Miyata Y, Nakayama H, Okumura S, Adachi S, Yoshimura M, Okada M.

J Thorac Cardiovasc Surg. 2012 Dec;144(6):1365-71. doi: 10.1016/j.jtcvs.2012.07.012. Epub 2012 Aug 9.


Value of baseline positron emission tomography for predicting overall survival in patient with nonmetastatic esophageal or gastroesophageal junction carcinoma.

Hong D, Lunagomez S, Kim EE, Lee JH, Bresalier RS, Swisher SG, Wu TT, Morris J, Liao Z, Komaki R, Ajani JA.

Cancer. 2005 Oct 15;104(8):1620-6.


The predictive and prognostic values of factors associated with visceral pleural involvement in resected lung adenocarcinomas.

Zhang H, Lu C, Lu Y, Yu B, Lv F, Zhu Z.

Onco Targets Ther. 2016 Apr 20;9:2337-48. doi: 10.2147/OTT.S100965. eCollection 2016.


Anatomical Segmentectomy and Wedge Resections Are Associated with Comparable Outcomes for Patients with Small cT1N0 Non-Small Cell Lung Cancer.

Altorki NK, Kamel MK, Narula N, Ghaly G, Nasar A, Rahouma M, Lee PC, Port JL, Stiles BM.

J Thorac Oncol. 2016 Nov;11(11):1984-1992. doi: 10.1016/j.jtho.2016.06.031. Epub 2016 Aug 3.


Solid predominant histologic subtype and early recurrence predict poor postrecurrence survival in patients with stage I lung adenocarcinoma.

Luo J, Wang R, Han B, Zhang J, Zhao H, Fang W, Luo Q, Yang J, Yang Y, Zhu L, Chen T, Cheng X, Huang Q, Wang Y, Zheng J, Chen H.

Oncotarget. 2017 Jan 24;8(4):7050-7058. doi: 10.18632/oncotarget.12540.

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