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Items: 1 to 20 of 99

1.

miR526b and miR655 Induce Oxidative Stress in Breast Cancer.

Shin B, Feser R, Nault B, Hunter S, Maiti S, Ugwuagbo KC, Majumder M.

Int J Mol Sci. 2019 Aug 19;20(16). pii: E4039. doi: 10.3390/ijms20164039.

2.

Mir526b and Mir655 Promote Tumour Associated Angiogenesis and Lymphangiogenesis in Breast Cancer.

Hunter S, Nault B, Ugwuagbo KC, Maiti S, Majumder M.

Cancers (Basel). 2019 Jul 4;11(7). pii: E938. doi: 10.3390/cancers11070938.

3.

COX-2 induces oncogenic micro RNA miR655 in human breast cancer.

Majumder M, Dunn L, Liu L, Hasan A, Vincent K, Brackstone M, Hess D, Lala PK.

Sci Rep. 2018 Jan 10;8(1):327. doi: 10.1038/s41598-017-18612-3.

4.

MicroRNA‑655 suppresses cell proliferation and invasion in oral squamous cell carcinoma by directly targeting metadherin and regulating the PTEN/AKT pathway.

Wang Q, Lv L, Li Y, Ji H.

Mol Med Rep. 2018 Sep;18(3):3106-3114. doi: 10.3892/mmr.2018.9292. Epub 2018 Jul 16.

PMID:
30015840
5.

EP4 as a Therapeutic Target for Aggressive Human Breast Cancer.

Majumder M, Nandi P, Omar A, Ugwuagbo KC, Lala PK.

Int J Mol Sci. 2018 Mar 29;19(4). pii: E1019. doi: 10.3390/ijms19041019. Review.

6.

Role of thioredoxin reductase 1 and thioredoxin interacting protein in prognosis of breast cancer.

Cadenas C, Franckenstein D, Schmidt M, Gehrmann M, Hermes M, Geppert B, Schormann W, Maccoux LJ, Schug M, Schumann A, Wilhelm C, Freis E, Ickstadt K, Rahnenführer J, Baumbach JI, Sickmann A, Hengstler JG.

Breast Cancer Res. 2010;12(3):R44. doi: 10.1186/bcr2599. Epub 2010 Jun 28.

7.

Induction of Oxidative Stress Through Inhibition of Thioredoxin Reductase 1 Is an Effective Therapeutic Approach for Hepatocellular Carcinoma.

Lee D, Xu IM, Chiu DK, Leibold J, Tse AP, Bao MH, Yuen VW, Chan CY, Lai RK, Chin DW, Chan DF, Cheung TT, Chok SH, Wong CM, Lowe SW, Ng IO, Wong CC.

Hepatology. 2019 Apr;69(4):1768-1786. doi: 10.1002/hep.30467. Epub 2019 Mar 21.

PMID:
30561826
8.

miR-500a-5p regulates oxidative stress response genes in breast cancer and predicts cancer survival.

Degli Esposti D, Aushev VN, Lee E, Cros MP, Zhu J, Herceg Z, Chen J, Hernandez-Vargas H.

Sci Rep. 2017 Nov 21;7(1):15966. doi: 10.1038/s41598-017-16226-3.

9.

MicroRNA-124 regulates the radiosensitivity of non-small cell lung cancer cells by targeting TXNRD1.

Hao C, Xu X, Ma J, Xia J, Dai B, Liu L, Ma Y.

Oncol Lett. 2017 Apr;13(4):2071-2078. doi: 10.3892/ol.2017.5701. Epub 2017 Feb 8.

10.

PCK1 Downregulation Promotes TXNRD1 Expression and Hepatoma Cell Growth via the Nrf2/Keap1 Pathway.

Tuo L, Xiang J, Pan X, Gao Q, Zhang G, Yang Y, Liang L, Xia J, Wang K, Tang N.

Front Oncol. 2018 Dec 17;8:611. doi: 10.3389/fonc.2018.00611. eCollection 2018.

11.

The production of reactive oxygen species enhanced with the reduction of menadione by active thioredoxin reductase.

Li J, Zuo X, Cheng P, Ren X, Sun S, Xu J, Holmgren A, Lu J.

Metallomics. 2019 Sep 1;11(9):1490-1497. doi: 10.1039/c9mt00133f. Epub 2019 Jul 30.

PMID:
31359011
12.

MicroRNA‑655 inhibits cell proliferation and invasion in epithelial ovarian cancer by directly targeting vascular endothelial growth factor.

Zhao Z, Yang S, Cheng Y, Zhao X.

Mol Med Rep. 2018 Aug;18(2):1878-1884. doi: 10.3892/mmr.2018.9090. Epub 2018 May 29.

PMID:
29845206
13.

Role of TGF-β1/miR-382-5p/SOD2 axis in the induction of oxidative stress in CD34+ cells from primary myelofibrosis.

Rossi C, Zini R, Rontauroli S, Ruberti S, Prudente Z, Barbieri G, Bianchi E, Salati S, Genovese E, Bartalucci N, Guglielmelli P, Tagliafico E, Rosti V, Barosi G, Vannucchi AM, Manfredini R; AGIMM (AIRC-Gruppo Italiano Malattie Mieloproliferative) investigators.

Mol Oncol. 2018 Dec;12(12):2102-2123. doi: 10.1002/1878-0261.12387. Epub 2018 Nov 16.

14.

Ethanol exposure induces the cancer-associated fibroblast phenotype and lethal tumor metabolism: implications for breast cancer prevention.

Sanchez-Alvarez R, Martinez-Outschoorn UE, Lin Z, Lamb R, Hulit J, Howell A, Sotgia F, Rubin E, Lisanti MP.

Cell Cycle. 2013 Jan 15;12(2):289-301. doi: 10.4161/cc.23109. Epub 2012 Jan 15.

15.

COX-2 Elevates Oncogenic miR-526b in Breast Cancer by EP4 Activation.

Majumder M, Landman E, Liu L, Hess D, Lala PK.

Mol Cancer Res. 2015 Jun;13(6):1022-33. doi: 10.1158/1541-7786.MCR-14-0543. Epub 2015 Mar 2.

16.

Homozygous mutation in TXNRD1 is associated with genetic generalized epilepsy.

Kudin AP, Baron G, Zsurka G, Hampel KG, Elger CE, Grote A, Weber Y, Lerche H, Thiele H, Nürnberg P, Schulz H, Ruppert AK, Sander T, Cheng Q, Arnér ES, Schomburg L, Seeher S, Fradejas-Villar N, Schweizer U, Kunz WS.

Free Radic Biol Med. 2017 May;106:270-277. doi: 10.1016/j.freeradbiomed.2017.02.040. Epub 2017 Feb 21.

PMID:
28232204
17.

Loss of thioredoxin reductase 1 renders tumors highly susceptible to pharmacologic glutathione deprivation.

Mandal PK, Schneider M, Kölle P, Kuhlencordt P, Förster H, Beck H, Bornkamm GW, Conrad M.

Cancer Res. 2010 Nov 15;70(22):9505-14. doi: 10.1158/0008-5472.CAN-10-1509. Epub 2010 Nov 2.

18.

Induced peroxidase and cytoprotective enzyme expressions support adaptation of HUVECs to sustain subsequent H2O2 exposure.

Patel H, Chen J, Kavdia M.

Microvasc Res. 2016 Jan;103:1-10. doi: 10.1016/j.mvr.2015.09.003. Epub 2015 Sep 25.

19.

The expression and activity of thioredoxin reductase 1 splice variants v1 and v2 regulate the expression of genes associated with differentiation and adhesion.

Nalvarte I, Damdimopoulos AE, Rüegg J, Spyrou G.

Biosci Rep. 2015 Oct 13;35(6). pii: e00269. doi: 10.1042/BSR20150236.

20.

Glucose-sensing microRNA-21 disrupts ROS homeostasis and impairs antioxidant responses in cellular glucose variability.

La Sala L, Mrakic-Sposta S, Micheloni S, Prattichizzo F, Ceriello A.

Cardiovasc Diabetol. 2018 Jul 23;17(1):105. doi: 10.1186/s12933-018-0748-2.

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