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Mild hypothermia improves neurological outcome in mice after cardiopulmonary resuscitation through Silent Information Regulator 1-actviated autophagy.

Wei H, Yin M, Lu Y, Yang Y, Li B, Liao XX, Dai G, Jing X, Xiong Y, Hu C.

Cell Death Discov. 2019 Aug 13;5:129. doi: 10.1038/s41420-019-0209-z. eCollection 2019.


Effects of mild hypothermia on the ROS and expression of caspase-3 mRNA and LC3 of hippocampus nerve cells in rats after cardiopulmonary resuscitation.

Lu J, Shen Y, Qian HY, Liu LJ, Zhou BC, Xiao Y, Mao JN, An GY, Rui MZ, Wang T, Zhu CL.

World J Emerg Med. 2014;5(4):298-305. doi: 10.5847/wjem.j.issn.1920-8642.2014.04.010.


Mild hypothermia protects hippocampal neurons against oxygen-glucose deprivation/reperfusion-induced injury by improving lysosomal function and autophagic flux.

Zhou T, Liang L, Liang Y, Yu T, Zeng C, Jiang L.

Exp Cell Res. 2017 Sep 15;358(2):147-160. doi: 10.1016/j.yexcr.2017.06.010. Epub 2017 Jun 15.


Hydrogen sulfide improves survival after cardiac arrest and cardiopulmonary resuscitation via a nitric oxide synthase 3-dependent mechanism in mice.

Minamishima S, Bougaki M, Sips PY, Yu JD, Minamishima YA, Elrod JW, Lefer DJ, Bloch KD, Ichinose F.

Circulation. 2009 Sep 8;120(10):888-96. doi: 10.1161/CIRCULATIONAHA.108.833491. Epub 2009 Aug 24.


Beneficial effects of nitric oxide on outcomes after cardiac arrest and cardiopulmonary resuscitation in hypothermia-treated mice.

Kida K, Shirozu K, Yu B, Mandeville JB, Bloch KD, Ichinose F.

Anesthesiology. 2014 Apr;120(4):880-9. doi: 10.1097/ALN.0000000000000149.


Extracranial hypothermia during cardiac arrest and cardiopulmonary resuscitation is neuroprotective in vivo.

Hutchens MP, Fujiyoshi T, Koerner IP, Herson PS.

Ther Hypothermia Temp Manag. 2014 Jun;4(2):79-87. doi: 10.1089/ther.2014.0003. Epub 2014 May 27.


The Role of Cranial Temperature in Neuroprotection by Sodium Hydrogen Sulfide After Cardiac Arrest in Mice.

Nakayama S, Taguchi N, Tanaka M.

Ther Hypothermia Temp Manag. 2018 Feb 12. doi: 10.1089/ther.2017.0054. [Epub ahead of print]


[Effects of mild hypothermia on β-adrenergic signaling pathway in a cardiac arrest swine model].

Zhu F, Ji X, Zhong X, Hu H, Liang L, Chen J, Shang D.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 Feb;30(2):134-139. doi: 10.3760/cma.j.issn.2095-4352.2018.02.008. Chinese.


Mitochondria-targeted hydrogen sulfide donor AP39 improves neurological outcomes after cardiac arrest in mice.

Ikeda K, Marutani E, Hirai S, Wood ME, Whiteman M, Ichinose F.

Nitric Oxide. 2015 Sep 15;49:90-6. doi: 10.1016/j.niox.2015.05.001. Epub 2015 May 7.


[Therapeutic hypothermia reduced brain damage on rats after cardiopulmonary resuscitation by activating III-type PI3K pathway to increase autophagy].

Xiao Y, Zhao X, Zhu J, Zou Q, Liu L.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2019 Jan;31(1):55-60. doi: 10.3760/cma.j.issn.2095-4352.2019.01.012. Chinese.


[Effect of pre-arrest and post-arrest mild hypothermia on myocardial function of ventricular fibrillation after restoration of spontaneous circulation in rabbits].

Li Y, Fan Z, Qin J, Jiang L, Hua Q, Li J.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2015 Mar;27(3):185-9. doi: 10.3760/cma.j.issn.2095-4352.2015.03.006. Chinese.


Inhaled nitric oxide improves outcomes after successful cardiopulmonary resuscitation in mice.

Minamishima S, Kida K, Tokuda K, Wang H, Sips PY, Kosugi S, Mandeville JB, Buys ES, Brouckaert P, Liu PK, Liu CH, Bloch KD, Ichinose F.

Circulation. 2011 Oct 11;124(15):1645-53. doi: 10.1161/CIRCULATIONAHA.111.025395. Epub 2011 Sep 19.


[Protective effects of endovascular cooling treatment on post-resuscitation syndrome and its mechanism].

Zou Y, Chen L, Hua T, Yang M.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue. 2018 Sep;30(9):888-893. doi: 10.3760/cma.j.issn.2095-4352.2018.09.013. Chinese.


Improvement in Outcomes After Cardiac Arrest and Resuscitation by Inhibition of S-Nitrosoglutathione Reductase.

Hayashida K, Bagchi A, Miyazaki Y, Hirai S, Seth D, Silverman MG, Rezoagli E, Marutani E, Mori N, Magliocca A, Liu X, Berra L, Hindle AG, Donnino MW, Malhotra R, Bradley MO, Stamler JS, Ichinose F.

Circulation. 2019 Feb 5;139(6):815-827. doi: 10.1161/CIRCULATIONAHA.117.032488.


Effects of adenosine monophosphate on induction of therapeutic hypothermia and neuronal damage after cardiopulmonary resuscitation in rats.

Knapp J, Schneider A, Nees C, Bruckner T, Böttiger BW, Popp E.

Resuscitation. 2014 Sep;85(9):1291-7. doi: 10.1016/j.resuscitation.2014.05.030. Epub 2014 Jun 27.


Moderate brain hypothermia started before resuscitation improves survival and neurobehavioral outcomes after CA/CPR in mice.

Jang MS, Oh SK, Lee SW, Jeong SH, Kim H.

Am J Emerg Med. 2019 Jan 17. pii: S0735-6757(19)30027-0. doi: 10.1016/j.ajem.2019.01.027. [Epub ahead of print]


cPKCγ-Modulated Sequential Reactivation of mTOR Inhibited Autophagic Flux in Neurons Exposed to Oxygen Glucose Deprivation/Reperfusion.

Hua R, Han S, Zhang N, Dai Q, Liu T, Li J.

Int J Mol Sci. 2018 May 6;19(5). pii: E1380. doi: 10.3390/ijms19051380.


The effects of adenocaine (adenosine and lidocaine) on early post-resuscitation cardiac and neurological dysfunction in a porcine model of cardiac arrest.

Granfeldt A, Shi W, Schmarkey SL, Jiang R, Bone CC, Cline JM, Wogensen L, Dobson GP, Tønnesen E, Vinten-Johansen J.

Resuscitation. 2013 Nov;84(11):1611-8. doi: 10.1016/j.resuscitation.2013.07.001. Epub 2013 Jul 11.


Sodium sulfide prevents water diffusion abnormality in the brain and improves long term outcome after cardiac arrest in mice.

Kida K, Minamishima S, Wang H, Ren J, Yigitkanli K, Nozari A, Mandeville JB, Liu PK, Liu CH, Ichinose F.

Resuscitation. 2012 Oct;83(10):1292-7. doi: 10.1016/j.resuscitation.2012.02.020. Epub 2012 Feb 25.


Intra-cardiopulmonary resuscitation hypothermia with and without volume loading in an ischemic model of cardiac arrest.

Yannopoulos D, Zviman M, Castro V, Kolandaivelu A, Ranjan R, Wilson RF, Halperin HR.

Circulation. 2009 Oct 6;120(14):1426-35. doi: 10.1161/CIRCULATIONAHA.109.848424. Epub 2009 Sep 21.


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