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Items: 1 to 20 of 95

1.

N-glycosylation-defective splice variants of neuropilin-1 promote metastasis by activating endosomal signals.

Huang X, Ye Q, Chen M, Li A, Mi W, Fang Y, Zaytseva YY, O'Connor KL, Vander Kooi CW, Liu S, She QB.

Nat Commun. 2019 Aug 16;10(1):3708. doi: 10.1038/s41467-019-11580-4.

2.

NRP1 knockdown promotes the migration and invasion of human neuroblastoma-derived SK‑N‑AS cells via the activation of β1 integrin expression.

Ishizuka Y, Koshinaga T, Hirano T, Nagasaki-Maeoka E, Watanabe Y, Hoshi R, Yoshizawa S, Sugito K, Kawashima H, Uekusa S, Fukuda N, Soma M, Fujiwara K.

Int J Oncol. 2018 Jul;53(1):159-166. doi: 10.3892/ijo.2018.4397. Epub 2018 May 7.

PMID:
29750423
3.

A Novel Physiological Glycosaminoglycan-Deficient Splice Variant of Neuropilin-1 Is Anti-Tumorigenic In Vitro and In Vivo.

Hendricks C, Dubail J, Brohée L, Delforge Y, Colige A, Deroanne C.

PLoS One. 2016 Oct 31;11(10):e0165153. doi: 10.1371/journal.pone.0165153. eCollection 2016.

4.

Neuropilin-1 mediates PDGF stimulation of vascular smooth muscle cell migration and signalling via p130Cas.

Pellet-Many C, Frankel P, Evans IM, Herzog B, Jünemann-Ramírez M, Zachary IC.

Biochem J. 2011 May 1;435(3):609-18. doi: 10.1042/BJ20100580.

5.

Co-targeting of EGF receptor and neuropilin-1 overcomes cetuximab resistance in pancreatic ductal adenocarcinoma with integrin β1-driven Src-Akt bypass signaling.

Kim YJ, Jung K, Baek DS, Hong SS, Kim YS.

Oncogene. 2017 May 4;36(18):2543-2552. doi: 10.1038/onc.2016.407. Epub 2016 Oct 31.

PMID:
27797376
6.

Neuropilin-1 exerts co-receptor function for TGF-beta-1 on the membrane of cancer cells and enhances responses to both latent and active TGF-beta.

Glinka Y, Stoilova S, Mohammed N, Prud'homme GJ.

Carcinogenesis. 2011 Apr;32(4):613-21. doi: 10.1093/carcin/bgq281. Epub 2010 Dec 24.

PMID:
21186301
7.

Neuropilin-1 promotes human glioma progression through potentiating the activity of the HGF/SF autocrine pathway.

Hu B, Guo P, Bar-Joseph I, Imanishi Y, Jarzynka MJ, Bogler O, Mikkelsen T, Hirose T, Nishikawa R, Cheng SY.

Oncogene. 2007 Aug 16;26(38):5577-86. Epub 2007 Mar 19.

8.

Calreticulin promotes migration and invasion of esophageal cancer cells by upregulating neuropilin-1 expression via STAT5A.

Shi F, Shang L, Pan BQ, Wang XM, Jiang YY, Hao JJ, Zhang Y, Cai Y, Xu X, Zhan QM, Wang MR.

Clin Cancer Res. 2014 Dec 1;20(23):6153-62. doi: 10.1158/1078-0432.CCR-14-0583. Epub 2014 Sep 17.

9.

Neuropilin-1 and neuropilin-2 act as coreceptors, potentiating proangiogenic activity.

Sulpice E, Plouët J, Bergé M, Allanic D, Tobelem G, Merkulova-Rainon T.

Blood. 2008 Feb 15;111(4):2036-45. Epub 2007 Dec 7.

PMID:
18065694
10.

Neuropilin-1 antagonism in human carcinoma cells inhibits migration and enhances chemosensitivity.

Jia H, Cheng L, Tickner M, Bagherzadeh A, Selwood D, Zachary I.

Br J Cancer. 2010 Feb 2;102(3):541-52. doi: 10.1038/sj.bjc.6605539. Epub 2010 Jan 19.

11.

Neuropilin-1/GIPC1 signaling regulates alpha5beta1 integrin traffic and function in endothelial cells.

Valdembri D, Caswell PT, Anderson KI, Schwarz JP, König I, Astanina E, Caccavari F, Norman JC, Humphries MJ, Bussolino F, Serini G.

PLoS Biol. 2009 Jan 27;7(1):e25. doi: 10.1371/journal.pbio.1000025.

12.

Met endosomal signalling: in the right place, at the right time.

Barrow-McGee R, Kermorgant S.

Int J Biochem Cell Biol. 2014 Apr;49:69-74. doi: 10.1016/j.biocel.2014.01.009. Epub 2014 Jan 16. Review.

PMID:
24440758
13.

Vascular endothelial growth factor and semaphorin induce neuropilin-1 endocytosis via separate pathways.

Salikhova A, Wang L, Lanahan AA, Liu M, Simons M, Leenders WP, Mukhopadhyay D, Horowitz A.

Circ Res. 2008 Sep 12;103(6):e71-9. doi: 10.1161/CIRCRESAHA.108.183327. Epub 2008 Aug 21. Erratum in: Circ Res. 2010 Oct 29;107(9):e14.

14.

Chondroitin sulphate-modified neuropilin 1 is expressed in human tumour cells and modulates 3D invasion in the U87MG human glioblastoma cell line through a p130Cas-mediated pathway.

Frankel P, Pellet-Many C, Lehtolainen P, D'Abaco GM, Tickner ML, Cheng L, Zachary IC.

EMBO Rep. 2008 Oct;9(10):983-9. doi: 10.1038/embor.2008.151. Epub 2008 Aug 15.

15.

The neuropilin 1 cytoplasmic domain is required for VEGF-A-dependent arteriogenesis.

Lanahan A, Zhang X, Fantin A, Zhuang Z, Rivera-Molina F, Speichinger K, Prahst C, Zhang J, Wang Y, Davis G, Toomre D, Ruhrberg C, Simons M.

Dev Cell. 2013 Apr 29;25(2):156-68. doi: 10.1016/j.devcel.2013.03.019.

16.

Neuropilin-1-dependent regulation of EGF-receptor signaling.

Rizzolio S, Rabinowicz N, Rainero E, Lanzetti L, Serini G, Norman J, Neufeld G, Tamagnone L.

Cancer Res. 2012 Nov 15;72(22):5801-11. doi: 10.1158/0008-5472.CAN-12-0995. Epub 2012 Sep 17.

17.

Prognostic value and in vitro biological relevance of Neuropilin 1 and Neuropilin 2 in osteosarcoma.

Boro A, Arlt MJ, Lengnick H, Robl B, Husmann M, Bertz J, Born W, Fuchs B.

Am J Transl Res. 2015 Mar 15;7(3):640-53. eCollection 2015.

18.

Neuropilin-1 is a receptor for extracellular miRNA and AGO2/miRNA complexes and mediates the internalization of miRNAs that modulate cell function.

Prud'homme GJ, Glinka Y, Lichner Z, Yousef GM.

Oncotarget. 2016 Oct 18;7(42):68057-68071. doi: 10.18632/oncotarget.10929.

19.

Neuropilin-1 promotes epithelial-to-mesenchymal transition by stimulating nuclear factor-kappa B and is associated with poor prognosis in human oral squamous cell carcinoma.

Chu W, Song X, Yang X, Ma L, Zhu J, He M, Wang Z, Wu Y.

PLoS One. 2014 Jul 7;9(7):e101931. doi: 10.1371/journal.pone.0101931. eCollection 2014.

20.

Neuropilin-1 is a receptor for transforming growth factor beta-1, activates its latent form, and promotes regulatory T cell activity.

Glinka Y, Prud'homme GJ.

J Leukoc Biol. 2008 Jul;84(1):302-10. doi: 10.1189/jlb.0208090. Epub 2008 Apr 24.

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