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Items: 1 to 20 of 96

1.

Sulfonamide-Based Inhibitors of Biotin Protein Ligase as New Antibiotic Leads.

Lee KJ, Tieu W, Blanco-Rodriguez B, Paparella AS, Yu J, Hayes A, Feng J, Marshall AC, Noll B, Milne R, Cini D, Wilce MCJ, Booker GW, Bruning JB, Polyak SW, Abell AD.

ACS Chem Biol. 2019 Sep 20;14(9):1990-1997. doi: 10.1021/acschembio.9b00463. Epub 2019 Aug 21.

PMID:
31407891
2.

New Series of BPL Inhibitors To Probe the Ribose-Binding Pocket of Staphylococcus aureus Biotin Protein Ligase.

Feng J, Paparella AS, Tieu W, Heim D, Clark S, Hayes A, Booker GW, Polyak SW, Abell AD.

ACS Med Chem Lett. 2016 Oct 10;7(12):1068-1072. eCollection 2016 Dec 8.

3.

Biotin Protein Ligase Is a Target for New Antibacterials.

Feng J, Paparella AS, Booker GW, Polyak SW, Abell AD.

Antibiotics (Basel). 2016 Jul 25;5(3). pii: E26. doi: 10.3390/antibiotics5030026. Review.

4.

Structural characterization of Staphylococcus aureus biotin protein ligase and interaction partners: an antibiotic target.

Pendini NR, Yap MY, Traore DA, Polyak SW, Cowieson NP, Abell A, Booker GW, Wallace JC, Wilce JA, Wilce MC.

Protein Sci. 2013 Jun;22(6):762-73. doi: 10.1002/pro.2262. Erratum in: Protein Sci. 2014 Jan;23(1):121. Traore, D A K [added].

5.

Biotin analogues with antibacterial activity are potent inhibitors of biotin protein ligase.

Soares da Costa TP, Tieu W, Yap MY, Zvarec O, Bell JM, Turnidge JD, Wallace JC, Booker GW, Wilce MC, Abell AD, Polyak SW.

ACS Med Chem Lett. 2012 May 23;3(6):509-14. doi: 10.1021/ml300106p. eCollection 2012 Jun 14.

6.

Heterocyclic acyl-phosphate bioisostere-based inhibitors of Staphylococcus aureus biotin protein ligase.

Tieu W, Jarrad AM, Paparella AS, Keeling KA, Soares da Costa TP, Wallace JC, Booker GW, Polyak SW, Abell AD.

Bioorg Med Chem Lett. 2014 Oct 1;24(19):4689-4693. doi: 10.1016/j.bmcl.2014.08.030. Epub 2014 Aug 19.

PMID:
25193234
7.

Structure guided design of biotin protein ligase inhibitors for antibiotic discovery.

Paparella AS, Soares da Costa TP, Yap MY, Tieu W, Wilce MC, Booker GW, Abell AD, Polyak SW.

Curr Top Med Chem. 2014;14(1):4-20. Review.

PMID:
24236729
8.

Halogenation of Biotin Protein Ligase Inhibitors Improves Whole Cell Activity against Staphylococcus aureus.

Paparella AS, Lee KJ, Hayes AJ, Feng J, Feng Z, Cini D, Deshmukh S, Booker GW, Wilce MCJ, Polyak SW, Abell AD.

ACS Infect Dis. 2018 Feb 9;4(2):175-184. doi: 10.1021/acsinfecdis.7b00134. Epub 2017 Nov 16.

PMID:
29131575
9.

Improved Synthesis of Biotinol-5'-AMP: Implications for Antibacterial Discovery.

Tieu W, Polyak SW, Paparella AS, Yap MY, Soares da Costa TP, Ng B, Wang G, Lumb R, Bell JM, Turnidge JD, Wilce MC, Booker GW, Abell AD.

ACS Med Chem Lett. 2014 Dec 11;6(2):216-20. doi: 10.1021/ml500475n. eCollection 2015 Feb 12.

10.

Dual roles of F123 in protein homodimerization and inhibitor binding to biotin protein ligase from Staphylococcus aureus.

Soares da Costa TP, Yap MY, Perugini MA, Wallace JC, Abell AD, Wilce MC, Polyak SW, Booker GW.

Mol Microbiol. 2014 Jan;91(1):110-20. doi: 10.1111/mmi.12446. Epub 2013 Nov 21.

11.

Selective inhibition of biotin protein ligase from Staphylococcus aureus.

Soares da Costa TP, Tieu W, Yap MY, Pendini NR, Polyak SW, Sejer Pedersen D, Morona R, Turnidge JD, Wallace JC, Wilce MC, Booker GW, Abell AD.

J Biol Chem. 2012 May 18;287(21):17823-32. doi: 10.1074/jbc.M112.356576. Epub 2012 Mar 21.

12.

Synthesis and evaluation of potent and selective beta(3) adrenergic receptor agonists containing acylsulfonamide, sulfonylsulfonamide, and sulfonylurea carboxylic acid isosteres.

Uehling DE, Donaldson KH, Deaton DN, Hyman CE, Sugg EE, Barrett DG, Hughes RG, Reitter B, Adkison KK, Lancaster ME, Lee F, Hart R, Paulik MA, Sherman BW, True T, Cowan C.

J Med Chem. 2002 Jan 31;45(3):567-83.

PMID:
11806709
13.

Active site conformational changes upon reaction intermediate biotinyl-5'-AMP binding in biotin protein ligase from Mycobacterium tuberculosis.

Ma Q, Akhter Y, Wilmanns M, Ehebauer MT.

Protein Sci. 2014 Jul;23(7):932-9. doi: 10.1002/pro.2475. Epub 2014 Apr 22.

14.

Antibacterial Activity and Mode of Action of a Sulfonamide-Based Class of Oxaborole Leucyl-tRNA-Synthetase Inhibitors.

Si Y, Basak S, Li Y, Merino J, Iuliano JN, Walker SG, Tonge PJ.

ACS Infect Dis. 2019 Jul 12;5(7):1231-1238. doi: 10.1021/acsinfecdis.9b00071. Epub 2019 May 1.

PMID:
31007018
15.

Phenazine antibiotic inspired discovery of potent bromophenazine antibacterial agents against Staphylococcus aureus and Staphylococcus epidermidis.

Borrero NV, Bai F, Perez C, Duong BQ, Rocca JR, Jin S, Huigens RW 3rd.

Org Biomol Chem. 2014 Feb 14;12(6):881-6. doi: 10.1039/c3ob42416b.

PMID:
24389824
16.

Protein biotinylation visualized by a complex structure of biotin protein ligase with a substrate.

Bagautdinov B, Matsuura Y, Bagautdinova S, Kunishima N.

J Biol Chem. 2008 May 23;283(21):14739-50. doi: 10.1074/jbc.M709116200. Epub 2008 Mar 26.

17.

Hydroxyethylene isostere inhibitors of human immunodeficiency virus-1 protease: structure-activity analysis using enzyme kinetics, X-ray crystallography, and infected T-cell assays.

Dreyer GB, Lambert DM, Meek TD, Carr TJ, Tomaszek TA Jr, Fernandez AV, Bartus H, Cacciavillani E, Hassell AM, Minnich M, et al.

Biochemistry. 1992 Jul 28;31(29):6646-59.

PMID:
1637805
18.

Combining the tail and the ring approaches for obtaining potent and isoform-selective carbonic anhydrase inhibitors: solution and X-ray crystallographic studies.

Bozdag M, Ferraroni M, Nuti E, Vullo D, Rossello A, Carta F, Scozzafava A, Supuran CT.

Bioorg Med Chem. 2014 Jan 1;22(1):334-40. doi: 10.1016/j.bmc.2013.11.016. Epub 2013 Nov 18.

PMID:
24300919
19.

Crystal structures of biotin protein ligase from Pyrococcus horikoshii OT3 and its complexes: structural basis of biotin activation.

Bagautdinov B, Kuroishi C, Sugahara M, Kunishima N.

J Mol Biol. 2005 Oct 21;353(2):322-33.

PMID:
16169557
20.

Design and synthesis of new hydroxyethylamines as inhibitors of D-alanyl-D-lactate ligase (VanA) and D-alanyl-D-alanine ligase (DdlB).

Sova M, Cadez G, Turk S, Majce V, Polanc S, Batson S, Lloyd AJ, Roper DI, Fishwick CW, Gobec S.

Bioorg Med Chem Lett. 2009 Mar 1;19(5):1376-9. doi: 10.1016/j.bmcl.2009.01.034. Epub 2009 Jan 19.

PMID:
19196510

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