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Items: 1 to 20 of 101


Regulatory networks in mechanotransduction reveal key genes in promoting cancer cell stemness and proliferation.

Huang W, Hu H, Zhang Q, Wu X, Wei F, Yang F, Gan L, Wang N, Yang X, Guo AY.

Oncogene. 2019 Aug 12. doi: 10.1038/s41388-019-0925-0. [Epub ahead of print]


Low Levels of Sox2 are required for Melanoma Tumor-Repopulating Cell Dormancy.

Jia Q, Yang F, Huang W, Zhang Y, Bao B, Li K, Wei F, Zhang C, Jia H.

Theranostics. 2019 Jan 1;9(2):424-435. doi: 10.7150/thno.29698. eCollection 2019.


MicroRNA MiR-199a-5p regulates smooth muscle cell proliferation and morphology by targeting WNT2 signaling pathway.

Hashemi Gheinani A, Burkhard FC, Rehrauer H, Aquino Fournier C, Monastyrskaya K.

J Biol Chem. 2015 Mar 13;290(11):7067-86. doi: 10.1074/jbc.M114.618694. Epub 2015 Jan 16.


miR-199a-5p confers tumor-suppressive role in triple-negative breast cancer.

Chen J, Shin VY, Siu MT, Ho JC, Cheuk I, Kwong A.

BMC Cancer. 2016 Nov 14;16(1):887.


miR-199a-3p targets stemness-related and mitogenic signaling pathways to suppress the expansion and tumorigenic capabilities of prostate cancer stem cells.

Liu R, Liu C, Zhang D, Liu B, Chen X, Rycaj K, Jeter C, Calhoun-Davis T, Li Y, Yang T, Wang J, Tang DG.

Oncotarget. 2016 Aug 30;7(35):56628-56642. doi: 10.18632/oncotarget.10652.


Nanoparticle delivery of stable miR-199a-5p agomir improves the osteogenesis of human mesenchymal stem cells via the HIF1a pathway.

Chen X, Gu S, Chen BF, Shen WL, Yin Z, Xu GW, Hu JJ, Zhu T, Li G, Wan C, Ouyang HW, Lee TL, Chan WY.

Biomaterials. 2015 Jun;53:239-50. doi: 10.1016/j.biomaterials.2015.02.071. Epub 2015 Mar 14.


MicroRNA profiling reveals dysregulated microRNAs and their target gene regulatory networks in cemento-ossifying fibroma.

Pereira TDSF, Brito JAR, Guimarães ALS, Gomes CC, de Lacerda JCT, de Castro WH, Coimbra RS, Diniz MG, Gomez RS.

J Oral Pathol Med. 2018 Jan;47(1):78-85. doi: 10.1111/jop.12650. Epub 2017 Nov 1.


Soft fibrin matrix downregulates DAB2IP to promote Nanog-dependent growth of colon tumor-repopulating cells.

Zhang M, Xu C, Wang HZ, Peng YN, Li HO, Zhou YJ, Liu S, Wang F, Liu L, Chang Y, Zhao Q, Liu J.

Cell Death Dis. 2019 Feb 15;10(3):151. doi: 10.1038/s41419-019-1309-7.


Efficient extravasation of tumor-repopulating cells depends on cell deformability.

Chen J, Zhou W, Jia Q, Chen J, Zhang S, Yao W, Wei F, Zhang Y, Yang F, Huang W, Zhang Y, Zhang H, Zhang Y, Huang B, Zhang Z, Jia H, Wang N.

Sci Rep. 2016 Jan 20;6:19304. doi: 10.1038/srep19304.


Investigation of key miRNAs and target genes in bladder cancer using miRNA profiling and bioinformatic tools.

Canturk KM, Ozdemir M, Can C, Öner S, Emre R, Aslan H, Cilingir O, Ciftci E, Celayir FM, Aldemir O, Özen M, Artan S.

Mol Biol Rep. 2014 Dec;41(12):8127-35. doi: 10.1007/s11033-014-3713-5. Epub 2014 Sep 5.


The deoxycholic acid targets miRNA-dependent CAC1 gene expression in multidrug resistance of human colorectal cancer.

Kong Y, Bai PS, Sun H, Nan KJ, Chen NZ, Qi XG.

Int J Biochem Cell Biol. 2012 Dec;44(12):2321-32. doi: 10.1016/j.biocel.2012.08.006. Epub 2012 Aug 10.


MicroRNA-199a is induced in dystrophic muscle and affects WNT signaling, cell proliferation, and myogenic differentiation.

Alexander MS, Kawahara G, Motohashi N, Casar JC, Eisenberg I, Myers JA, Gasperini MJ, Estrella EA, Kho AT, Mitsuhashi S, Shapiro F, Kang PB, Kunkel LM.

Cell Death Differ. 2013 Sep;20(9):1194-208. doi: 10.1038/cdd.2013.62. Epub 2013 Jun 14.


miR-199a-5p and miR-495 target GRP78 within UPR pathway of lung cancer.

Ahmadi A, Khansarinejad B, Hosseinkhani S, Ghanei M, Mowla SJ.

Gene. 2017 Jul 15;620:15-22. doi: 10.1016/j.gene.2017.03.032. Epub 2017 Mar 28.


Matrix softness regulates plasticity of tumour-repopulating cells via H3K9 demethylation and Sox2 expression.

Tan Y, Tajik A, Chen J, Jia Q, Chowdhury F, Wang L, Chen J, Zhang S, Hong Y, Yi H, Wu DC, Zhang Y, Wei F, Poh YC, Seong J, Singh R, Lin LJ, Doğanay S, Li Y, Jia H, Ha T, Wang Y, Huang B, Wang N.

Nat Commun. 2014 Aug 6;5:4619. doi: 10.1038/ncomms5619.


APC gene is modulated by hsa-miR-135b-5p in both diffuse and intestinal gastric cancer subtypes.

Magalhães L, Quintana LG, Lopes DCF, Vidal AF, Pereira AL, D'Araujo Pinto LC, de Jesus Viana Pinheiro J, Khayat AS, Goulart LR, Burbano R, de Assumpção PP, Ribeiro-Dos-Santos Â.

BMC Cancer. 2018 Oct 30;18(1):1055. doi: 10.1186/s12885-018-4980-7.


SRF expedites metastasis and modulates the epithelial to mesenchymal transition by regulating miR-199a-5p expression in human gastric cancer.

Zhao X, He L, Li T, Lu Y, Miao Y, Liang S, Guo H, Bai M, Xie H, Luo G, Zhou L, Shen G, Guo C, Bai F, Sun S, Wu K, Nie Y, Fan D.

Cell Death Differ. 2014 Dec;21(12):1900-13. doi: 10.1038/cdd.2014.109. Epub 2014 Aug 1.


IGF-I induces upregulation of DDR1 collagen receptor in breast cancer cells by suppressing MIR-199a-5p through the PI3K/AKT pathway.

Matà R, Palladino C, Nicolosi ML, Lo Presti AR, Malaguarnera R, Ragusa M, Sciortino D, Morrione A, Maggiolini M, Vella V, Belfiore A.

Oncotarget. 2016 Feb 16;7(7):7683-700. doi: 10.18632/oncotarget.6524.


MicroRNA Expression Profiling in Clear Cell Renal Cell Carcinoma: Identification and Functional Validation of Key miRNAs.

He H, Wang L, Zhou W, Zhang Z, Wang L, Xu S, Wang D, Dong J, Tang C, Tang H, Yi X, Ge J.

PLoS One. 2015 May 4;10(5):e0125672. doi: 10.1371/journal.pone.0125672. eCollection 2015.


MiR-30-5p suppresses cell chemoresistance and stemness in colorectal cancer through USP22/Wnt/β-catenin signaling axis.

Jiang S, Miao D, Wang M, Lv J, Wang Y, Tong J.

J Cell Mol Med. 2019 Jan;23(1):630-640. doi: 10.1111/jcmm.13968. Epub 2018 Oct 19.

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