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Items: 1 to 20 of 100

1.

A meta-opinion: cannabinoids delivered to oral mucosa by a spray for systemic absorption are rather ingested into gastro-intestinal tract: the influences of fed / fasting states.

Itin C, Domb AJ, Hoffman A.

Expert Opin Drug Deliv. 2019 Oct;16(10):1031-1035. doi: 10.1080/17425247.2019.1653852. Epub 2019 Aug 12.

PMID:
31393180
2.

Can oral fluid cannabinoid testing monitor medication compliance and/or cannabis smoking during oral THC and oromucosal Sativex administration?

Lee D, Karschner EL, Milman G, Barnes AJ, Goodwin RS, Huestis MA.

Drug Alcohol Depend. 2013 Jun 1;130(1-3):68-76. doi: 10.1016/j.drugalcdep.2012.10.011. Epub 2012 Nov 10.

3.

Piperine-pro-nanolipospheres as a novel oral delivery system of cannabinoids: Pharmacokinetic evaluation in healthy volunteers in comparison to buccal spray administration.

Cherniakov I, Izgelov D, Barasch D, Davidson E, Domb AJ, Hoffman A.

J Control Release. 2017 Nov 28;266:1-7. doi: 10.1016/j.jconrel.2017.09.011. Epub 2017 Sep 8.

PMID:
28890215
4.

Critical evaluation of permeation enhancers for oral mucosal drug delivery.

Sohi H, Ahuja A, Ahmad FJ, Khar RK.

Drug Dev Ind Pharm. 2010 Mar;36(3):254-82. doi: 10.1080/03639040903117348. Review.

PMID:
19663558
5.

Oral mucosal drug delivery: clinical pharmacokinetics and therapeutic applications.

Zhang H, Zhang J, Streisand JB.

Clin Pharmacokinet. 2002;41(9):661-80. Review.

PMID:
12126458
6.

PTL401, a New Formulation Based on Pro-Nano Dispersion Technology, Improves Oral Cannabinoids Bioavailability in Healthy Volunteers.

Atsmon J, Cherniakov I, Izgelov D, Hoffman A, Domb AJ, Deutsch L, Deutsch F, Heffetz D, Sacks H.

J Pharm Sci. 2018 May;107(5):1423-1429. doi: 10.1016/j.xphs.2017.12.020. Epub 2017 Dec 26.

PMID:
29287930
7.

The detection of THC, CBD and CBN in the oral fluid of Sativex® patients using two on-site screening tests and LC-MS/MS.

Molnar A, Fu S, Lewis J, Allsop DJ, Copeland J.

Forensic Sci Int. 2014 May;238:113-9. doi: 10.1016/j.forsciint.2014.03.004. Epub 2014 Mar 12.

PMID:
24699310
8.

Plasma cannabinoid pharmacokinetics following controlled oral delta9-tetrahydrocannabinol and oromucosal cannabis extract administration.

Karschner EL, Darwin WD, Goodwin RS, Wright S, Huestis MA.

Clin Chem. 2011 Jan;57(1):66-75. doi: 10.1373/clinchem.2010.152439. Epub 2010 Nov 15.

9.

A drug discovery case history of 'delta-9-tetrahydrocannabinol, cannabidiol'.

Tanasescu R, Rog D, Constantinescu CS.

Expert Opin Drug Discov. 2011 Apr;6(4):437-52. doi: 10.1517/17460441.2011.560935. Epub 2011 Mar 3.

PMID:
22646020
10.
11.

Abuse potential and psychoactive effects of δ-9-tetrahydrocannabinol and cannabidiol oromucosal spray (Sativex), a new cannabinoid medicine.

Robson P.

Expert Opin Drug Saf. 2011 Sep;10(5):675-85. doi: 10.1517/14740338.2011.575778. Epub 2011 May 4. Review.

PMID:
21542664
12.

In Vivo Dissolution and Systemic Absorption of Immediate Release Ibuprofen in Human Gastrointestinal Tract under Fed and Fasted Conditions.

Koenigsknecht MJ, Baker JR, Wen B, Frances A, Zhang H, Yu A, Zhao T, Tsume Y, Pai MP, Bleske BE, Zhang X, Lionberger R, Lee A, Amidon GL, Hasler WL, Sun D.

Mol Pharm. 2017 Dec 4;14(12):4295-4304. doi: 10.1021/acs.molpharmaceut.7b00425. Epub 2017 Oct 5.

PMID:
28937221
13.

Cannabinoids: novel medicines for the treatment of Huntington's disease.

Sagredo O, Pazos MR, Valdeolivas S, Fernandez-Ruiz J.

Recent Pat CNS Drug Discov. 2012 Apr 1;7(1):41-8. Review.

PMID:
22280340
15.

Subjective and physiological effects after controlled Sativex and oral THC administration.

Karschner EL, Darwin WD, McMahon RP, Liu F, Wright S, Goodwin RS, Huestis MA.

Clin Pharmacol Ther. 2011 Mar;89(3):400-7. doi: 10.1038/clpt.2010.318. Epub 2011 Feb 2.

16.

Differential pharmacokinetics of diclofenac potassium for oral solution vs immediate-release tablets from a randomized trial: effect of fed and fasting conditions.

Chen C, Bujanover S, Kareht S, Rapoport AM.

Headache. 2015 Feb;55(2):265-75. doi: 10.1111/head.12483. Epub 2014 Dec 24.

PMID:
25546369
17.
19.

Single-Dose Pharmacokinetics of Oral Cannabidiol Following Administration of PTL101: A New Formulation Based on Gelatin Matrix Pellets Technology.

Atsmon J, Heffetz D, Deutsch L, Deutsch F, Sacks H.

Clin Pharmacol Drug Dev. 2018 Sep;7(7):751-758. doi: 10.1002/cpdd.408. Epub 2017 Nov 10.

PMID:
29125702
20.

Delivery of bioactive peptides and proteins across oral (buccal) mucosa.

Senel S, Kremer M, Nagy K, Squier C.

Curr Pharm Biotechnol. 2001 Jun;2(2):175-86. Review.

PMID:
11480421

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