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Items: 1 to 20 of 96

1.

Transplantation of microbiota from drug-free patients with schizophrenia causes schizophrenia-like abnormal behaviors and dysregulated kynurenine metabolism in mice.

Zhu F, Guo R, Wang W, Ju Y, Wang Q, Ma Q, Sun Q, Fan Y, Xie Y, Yang Z, Jie Z, Zhao B, Xiao L, Yang L, Zhang T, Liu B, Guo L, He X, Chen Y, Chen C, Gao C, Xu X, Yang H, Wang J, Dang Y, Madsen L, Brix S, Kristiansen K, Jia H, Ma X.

Mol Psychiatry. 2019 Aug 7. doi: 10.1038/s41380-019-0475-4. [Epub ahead of print]

PMID:
31391545
2.

Fecal microbiota transplantation from chronic unpredictable mild stress mice donors affects anxiety-like and depression-like behavior in recipient mice via the gut microbiota-inflammation-brain axis.

Li N, Wang Q, Wang Y, Sun A, Lin Y, Jin Y, Li X.

Stress. 2019 Sep;22(5):592-602. doi: 10.1080/10253890.2019.1617267. Epub 2019 May 24.

PMID:
31124390
3.

Gut microbiota regulates mouse behaviors through glucocorticoid receptor pathway genes in the hippocampus.

Luo Y, Zeng B, Zeng L, Du X, Li B, Huo R, Liu L, Wang H, Dong M, Pan J, Zheng P, Zhou C, Wei H, Xie P.

Transl Psychiatry. 2018 Sep 7;8(1):187. doi: 10.1038/s41398-018-0240-5.

4.

Post-weaning social isolation of rats leads to long-term disruption of the gut microbiota-immune-brain axis.

Dunphy-Doherty F, O'Mahony SM, Peterson VL, O'Sullivan O, Crispie F, Cotter PD, Wigmore P, King MV, Cryan JF, Fone KCF.

Brain Behav Immun. 2018 Feb;68:261-273. doi: 10.1016/j.bbi.2017.10.024. Epub 2017 Nov 6.

PMID:
29104061
5.

Transferring the blues: Depression-associated gut microbiota induces neurobehavioural changes in the rat.

Kelly JR, Borre Y, O' Brien C, Patterson E, El Aidy S, Deane J, Kennedy PJ, Beers S, Scott K, Moloney G, Hoban AE, Scott L, Fitzgerald P, Ross P, Stanton C, Clarke G, Cryan JF, Dinan TG.

J Psychiatr Res. 2016 Nov;82:109-18. doi: 10.1016/j.jpsychires.2016.07.019. Epub 2016 Jul 25.

PMID:
27491067
6.

Reversal of imbalance between kynurenic acid and 3-hydroxykynurenine by antipsychotics in medication-naïve and medication-free schizophrenic patients.

Myint AM, Schwarz MJ, Verkerk R, Mueller HH, Zach J, Scharpé S, Steinbusch HW, Leonard BE, Kim YK.

Brain Behav Immun. 2011 Nov;25(8):1576-81. doi: 10.1016/j.bbi.2011.05.005. Epub 2011 May 17.

PMID:
21620952
7.

Transplantation of fecal microbiota from patients with irritable bowel syndrome alters gut function and behavior in recipient mice.

De Palma G, Lynch MD, Lu J, Dang VT, Deng Y, Jury J, Umeh G, Miranda PM, Pigrau Pastor M, Sidani S, Pinto-Sanchez MI, Philip V, McLean PG, Hagelsieb MG, Surette MG, Bergonzelli GE, Verdu EF, Britz-McKibbin P, Neufeld JD, Collins SM, Bercik P.

Sci Transl Med. 2017 Mar 1;9(379). pii: eaaf6397. doi: 10.1126/scitranslmed.aaf6397.

PMID:
28251905
8.

Kynurenine pathway metabolism and the microbiota-gut-brain axis.

Kennedy PJ, Cryan JF, Dinan TG, Clarke G.

Neuropharmacology. 2017 Jan;112(Pt B):399-412. doi: 10.1016/j.neuropharm.2016.07.002. Epub 2016 Jul 5. Review.

PMID:
27392632
9.

Cortical kynurenine pathway metabolism: a novel target for cognitive enhancement in Schizophrenia.

Wonodi I, Schwarcz R.

Schizophr Bull. 2010 Mar;36(2):211-8. doi: 10.1093/schbul/sbq002. Epub 2010 Feb 10. Review.

10.

Enteric Delivery of Regenerating Family Member 3 alpha Alters the Intestinal Microbiota and Controls Inflammation in Mice With Colitis.

Darnaud M, Dos Santos A, Gonzalez P, Augui S, Lacoste C, Desterke C, De Hertogh G, Valentino E, Braun E, Zheng J, Boisgard R, Neut C, Dubuquoy L, Chiappini F, Samuel D, Lepage P, Guerrieri F, Doré J, Bréchot C, Moniaux N, Faivre J.

Gastroenterology. 2018 Mar;154(4):1009-1023.e14. doi: 10.1053/j.gastro.2017.11.003. Epub 2017 Nov 11.

11.

Abnormal composition of gut microbiota contributes to delirium-like behaviors after abdominal surgery in mice.

Zhang J, Bi JJ, Guo GJ, Yang L, Zhu B, Zhan GF, Li S, Huang NN, Hashimoto K, Yang C, Luo AL.

CNS Neurosci Ther. 2019 Jun;25(6):685-696. doi: 10.1111/cns.13103. Epub 2019 Jan 24.

12.

Key role of gut microbiota in anhedonia-like phenotype in rodents with neuropathic pain.

Yang C, Fang X, Zhan G, Huang N, Li S, Bi J, Jiang R, Yang L, Miao L, Zhu B, Luo A, Hashimoto K.

Transl Psychiatry. 2019 Jan 31;9(1):57. doi: 10.1038/s41398-019-0379-8.

13.

Impaired kynurenine pathway metabolism in the prefrontal cortex of individuals with schizophrenia.

Sathyasaikumar KV, Stachowski EK, Wonodi I, Roberts RC, Rassoulpour A, McMahon RP, Schwarcz R.

Schizophr Bull. 2011 Nov;37(6):1147-56. doi: 10.1093/schbul/sbq112. Epub 2010 Oct 29.

14.

Intestinal microbiota impact sepsis associated encephalopathy via the vagus nerve.

Li S, Lv J, Li J, Zhao Z, Guo H, Zhang Y, Cheng S, Sun J, Pan H, Fan S, Li Z.

Neurosci Lett. 2018 Jan 1;662:98-104. doi: 10.1016/j.neulet.2017.10.008. Epub 2017 Oct 6.

15.

The kynurenine pathway in schizophrenia and bipolar disorder.

Erhardt S, Schwieler L, Imbeault S, Engberg G.

Neuropharmacology. 2017 Jan;112(Pt B):297-306. doi: 10.1016/j.neuropharm.2016.05.020. Epub 2016 May 28. Review.

PMID:
27245499
16.

Microbial regulation of hippocampal miRNA expression: Implications for transcription of kynurenine pathway enzymes.

Moloney GM, O'Leary OF, Salvo-Romero E, Desbonnet L, Shanahan F, Dinan TG, Clarke G, Cryan JF.

Behav Brain Res. 2017 Sep 15;334:50-54. doi: 10.1016/j.bbr.2017.07.026. Epub 2017 Jul 20.

PMID:
28736331
17.

Targeted deletion of kynurenine 3-monooxygenase in mice: a new tool for studying kynurenine pathway metabolism in periphery and brain.

Giorgini F, Huang SY, Sathyasaikumar KV, Notarangelo FM, Thomas MA, Tararina M, Wu HQ, Schwarcz R, Muchowski PJ.

J Biol Chem. 2013 Dec 20;288(51):36554-66. doi: 10.1074/jbc.M113.503813. Epub 2013 Nov 4.

18.

Activation of kynurenine pathway in ex vivo fibroblasts from patients with bipolar disorder or schizophrenia: cytokine challenge increases production of 3-hydroxykynurenine.

Johansson AS, Owe-Larsson B, Asp L, Kocki T, Adler M, Hetta J, Gardner R, Lundkvist GB, Urbanska EM, Karlsson H.

J Psychiatr Res. 2013 Nov;47(11):1815-23. doi: 10.1016/j.jpsychires.2013.08.008. Epub 2013 Aug 23.

PMID:
24012176
19.

Microbiota-Derived Metabolic Factors Reduce Campylobacteriosis in Mice.

Sun X, Winglee K, Gharaibeh RZ, Gauthier J, He Z, Tripathi P, Avram D, Bruner S, Fodor A, Jobin C.

Gastroenterology. 2018 May;154(6):1751-1763.e2. doi: 10.1053/j.gastro.2018.01.042. Epub 2018 Feb 1.

20.

Microorganisms, Tryptophan Metabolism, and Kynurenine Pathway: A Complex Interconnected Loop Influencing Human Health Status.

Dehhaghi M, Kazemi Shariat Panahi H, Guillemin GJ.

Int J Tryptophan Res. 2019 Jun 19;12:1178646919852996. doi: 10.1177/1178646919852996. eCollection 2019. Review.

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