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Items: 1 to 20 of 99

1.

Formononetin ameliorates cognitive disorder via PGC-1α pathway in neuroinflammation conditions in high-fat diet-induced mice.

Fu X, Qin T, Yu J, Jiao J, Ma Z, Fu Q, Deng X, Ma S.

CNS Neurol Disord Drug Targets. 2019 Aug 7. doi: 10.2174/1871527318666190807160137. [Epub ahead of print]

PMID:
31389320
2.

Thymol improves high-fat diet-induced cognitive deficits in mice via ameliorating brain insulin resistance and upregulating NRF2/HO-1 pathway.

FangFang, Li H, Qin T, Li M, Ma S.

Metab Brain Dis. 2017 Apr;32(2):385-393. doi: 10.1007/s11011-016-9921-z. Epub 2016 Oct 20.

PMID:
27761760
3.

Obesity caused by a high-fat diet regulates the Sirt1/PGC-1α/FNDC5/BDNF pathway to exacerbate isoflurane-induced postoperative cognitive dysfunction in older mice.

Zhao Z, Yao M, Wei L, Ge S.

Nutr Neurosci. 2019 Feb 22:1-12. doi: 10.1080/1028415X.2019.1581460. [Epub ahead of print]

PMID:
30794116
4.

High fat diet increases cognitive decline and neuroinflammation in a model of orexin loss.

Duffy CM, Hofmeister JJ, Nixon JP, Butterick TA.

Neurobiol Learn Mem. 2019 Jan;157:41-47. doi: 10.1016/j.nlm.2018.11.008. Epub 2018 Nov 22.

PMID:
30471346
5.

Bofutsushosan ameliorates obesity in mice through modulating PGC-1α expression in brown adipose tissues and inhibiting inflammation in white adipose tissues.

Chen YY, Yan Y, Zhao Z, Shi MJ, Zhang YB.

Chin J Nat Med. 2016 Jun;14(6):449-56. doi: 10.1016/S1875-5364(16)30042-5.

PMID:
27473963
6.

Neuroprotective Effects of Endurance Exercise Against High-Fat Diet-Induced Hippocampal Neuroinflammation.

Kang EB, Koo JH, Jang YC, Yang CH, Lee Y, Cosio-Lima LM, Cho JY.

J Neuroendocrinol. 2016 May;28(5). doi: 10.1111/jne.12385.

PMID:
26991447
7.

Juglanin ameliorates LPS-induced neuroinflammation in animal models of Parkinson's disease and cell culture via inactivating TLR4/NF-κB pathway.

Zhang FX, Xu RS.

Biomed Pharmacother. 2018 Jan;97:1011-1019. doi: 10.1016/j.biopha.2017.08.132. Epub 2017 Nov 8.

PMID:
29136779
8.
9.

PPARγ coactivator-1α (PGC-1α) protects neuroblastoma cells against amyloid-beta (Aβ) induced cell death and neuroinflammation via NF-κB pathway.

Zhang Y, Chen C, Jiang Y, Wang S, Wu X, Wang K.

BMC Neurosci. 2017 Sep 25;18(1):69. doi: 10.1186/s12868-017-0387-7.

10.

Galantamine improves cognition, hippocampal inflammation, and synaptic plasticity impairments induced by lipopolysaccharide in mice.

Liu Y, Zhang Y, Zheng X, Fang T, Yang X, Luo X, Guo A, Newell KA, Huang XF, Yu Y.

J Neuroinflammation. 2018 Apr 18;15(1):112. doi: 10.1186/s12974-018-1141-5.

11.

Voluntary alcohol consumption exacerbated high fat diet-induced cognitive deficits by NF-κB-calpain dependent apoptotic cell death in rat hippocampus: Ameliorative effect of melatonin.

Dwivedi DK, Kumar D, Kwatra M, Pandey SN, Choubey P, Lahkar M, Jangra A.

Biomed Pharmacother. 2018 Dec;108:1393-1403. doi: 10.1016/j.biopha.2018.09.173. Epub 2018 Oct 6.

12.

The Oral Pretreatment of Glycyrrhizin Prevents Surgery-Induced Cognitive Impairment in Aged Mice by Reducing Neuroinflammation and Alzheimer's-Related Pathology via HMGB1 Inhibition.

Kong ZH, Chen X, Hua HP, Liang L, Liu LJ.

J Mol Neurosci. 2017 Dec;63(3-4):385-395. doi: 10.1007/s12031-017-0989-7. Epub 2017 Oct 16.

PMID:
29034441
13.

Moderate treadmill exercise ameliorates amyloid-β-induced learning and memory impairment, possibly via increasing AMPK activity and up-regulation of the PGC-1α/FNDC5/BDNF pathway.

Azimi M, Gharakhanlou R, Naghdi N, Khodadadi D, Heysieattalab S.

Peptides. 2018 Apr;102:78-88. doi: 10.1016/j.peptides.2017.12.027. Epub 2018 Jan 5.

PMID:
29309801
14.

Early inflammation-associated factors blunt sterol regulatory element-binding proteins-1-mediated lipogenesis in high-fat diet-fed APPSWE /PSEN1dE9 mouse model of Alzheimer's disease.

Tang Y, Peng Y, Liu J, Shi L, Wang Y, Long J, Liu J.

J Neurochem. 2016 Feb;136(4):791-803. doi: 10.1111/jnc.13437. Epub 2015 Dec 10.

15.

High-fat diet inhibits PGC-1α suppressive effect on NFκB signaling in hepatocytes.

Barroso WA, Victorino VJ, Jeremias IC, Petroni RC, Ariga SKK, Salles TA, Barbeiro DF, de Lima TM, de Souza HP.

Eur J Nutr. 2018 Aug;57(5):1891-1900. doi: 10.1007/s00394-017-1472-5. Epub 2017 May 24.

PMID:
28540526
16.

Effect of high-fat diet on cognitive impairment in triple-transgenic mice model of Alzheimer's disease.

Sah SK, Lee C, Jang JH, Park GH.

Biochem Biophys Res Commun. 2017 Nov 4;493(1):731-736. doi: 10.1016/j.bbrc.2017.08.122. Epub 2017 Sep 1.

PMID:
28865961
17.

Chikusetsu saponin IVa ameliorates high fat diet-induced inflammation in adipose tissue of mice through inhibition of NLRP3 inflammasome activation and NF-κB signaling.

Yuan C, Liu C, Wang T, He Y, Zhou Z, Dun Y, Zhao H, Ren D, Wang J, Zhang C, Yuan D.

Oncotarget. 2017 May 9;8(19):31023-31040. doi: 10.18632/oncotarget.16052.

18.

Balasubramide derivative 3C modulates microglia activation via CaMKKβ-dependent AMPK/PGC-1α pathway in neuroinflammatory conditions.

Wang Y, Ruan W, Mi J, Xu J, Wang H, Cao Z, Saavedra JM, Zhang L, Lin H, Pang T.

Brain Behav Immun. 2018 Jan;67:101-117. doi: 10.1016/j.bbi.2017.08.006. Epub 2017 Aug 9.

PMID:
28803158
19.

High-fat diet-induced renal cell apoptosis and oxidative stress in spontaneously hypertensive rat are ameliorated by fenofibrate through the PPARα-FoxO3a-PGC-1α pathway.

Chung HW, Lim JH, Kim MY, Shin SJ, Chung S, Choi BS, Kim HW, Kim YS, Park CW, Chang YS.

Nephrol Dial Transplant. 2012 Jun;27(6):2213-25. doi: 10.1093/ndt/gfr613. Epub 2011 Nov 9.

PMID:
22076434
20.

Cardiotrophin-1 (CT-1) improves high fat diet-induced cognitive deficits in mice.

Wang D, Liu L, Yan J, Wu W, Zhu X, Wang Y.

Neurochem Res. 2015 Apr;40(4):843-53. doi: 10.1007/s11064-015-1535-z. Epub 2015 Feb 12.

PMID:
25672823

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