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Items: 1 to 20 of 102

1.

Hypoxia Up-regulates HIF Expression While Suppressing Cell Growth and NOTCH Activity in Leukaemia Cells.

Itoh M, Okuhashi Y, Takahashi Y, Sonoda Y, Mohammad S, Saito T, Shiratori E, Tohda S.

Anticancer Res. 2019 Aug;39(8):4165-4170. doi: 10.21873/anticanres.13575.

PMID:
31366501
2.

Regulation of HIF-1α signaling and chemoresistance in acute lymphocytic leukemia under hypoxic conditions of the bone marrow microenvironment.

Frolova O, Samudio I, Benito JM, Jacamo R, Kornblau SM, Markovic A, Schober W, Lu H, Qiu YH, Buglio D, McQueen T, Pierce S, Shpall E, Konoplev S, Thomas D, Kantarjian H, Lock R, Andreeff M, Konopleva M.

Cancer Biol Ther. 2012 Aug;13(10):858-70. doi: 10.4161/cbt.20838. Epub 2012 Aug 1.

3.

Effects of the HIF1 inhibitor, echinomycin, on growth and NOTCH signalling in leukaemia cells.

Yonekura S, Itoh M, Okuhashi Y, Takahashi Y, Ono A, Nara N, Tohda S.

Anticancer Res. 2013 Aug;33(8):3099-103.

PMID:
23898065
4.

Hypoxia inducible factor 2α/insulin-like growth factor receptor signal loop supports the proliferation and Oct-4 maintenance of mouse germline stem cells.

Huang YH, Lin MH, Wang PC, Wu YC, Chiang HL, Wang YL, Chang JH, Huang YK, Gu SY, Ho HN, Ling TY.

Mol Hum Reprod. 2014 Jun;20(6):526-37. doi: 10.1093/molehr/gau016. Epub 2014 Mar 5.

PMID:
24598112
5.

2-Methoxyestradiol inhibits hypoxia-induced scleroderma fibroblast collagen synthesis by phosphatidylinositol 3-kinase/Akt/mTOR signalling.

Zhou X, Liu C, Lu J, Zhu L, Li M.

Rheumatology (Oxford). 2018 Sep 1;57(9):1675-1684. doi: 10.1093/rheumatology/key166.

PMID:
29905853
6.

Notch1 is required for hypoxia-induced proliferation, invasion and chemoresistance of T-cell acute lymphoblastic leukemia cells.

Zou J, Li P, Lu F, Liu N, Dai J, Ye J, Qu X, Sun X, Ma D, Park J, Ji C.

J Hematol Oncol. 2013 Jan 5;6:3. doi: 10.1186/1756-8722-6-3.

7.

Notch-1 signaling regulates microglia activation via NF-κB pathway after hypoxic exposure in vivo and in vitro.

Yao L, Kan EM, Kaur C, Dheen ST, Hao A, Lu J, Ling EA.

PLoS One. 2013 Nov 6;8(11):e78439. doi: 10.1371/journal.pone.0078439. eCollection 2013.

8.

Notch Signaling Enhances Stemness by Regulating Metabolic Pathways Through Modifying p53, NF-κB, and HIF-1α.

Moriyama H, Moriyama M, Ozawa T, Tsuruta D, Iguchi T, Tamada S, Nakatani T, Nakagawa K, Hayakawa T.

Stem Cells Dev. 2018 Jul 1;27(13):935-947. doi: 10.1089/scd.2017.0260. Epub 2018 May 30.

PMID:
29717634
9.

Activation of hypoxia-inducible factor 1 in human T-cell leukaemia virus type 1-infected cell lines and primary adult T-cell leukaemia cells.

Tomita M, Semenza GL, Michiels C, Matsuda T, Uchihara JN, Okudaira T, Tanaka Y, Taira N, Ohshiro K, Mori N.

Biochem J. 2007 Sep 1;406(2):317-23. Retraction in: Biochem J. 2011 Mar 15;434(3):571.

10.

Inflammatory stimulation and hypoxia cooperatively activate HIF-1{alpha} in bronchial epithelial cells: involvement of PI3K and NF-{kappa}B.

Jiang H, Zhu YS, Xu H, Sun Y, Li QF.

Am J Physiol Lung Cell Mol Physiol. 2010 May;298(5):L660-9. doi: 10.1152/ajplung.00394.2009. Epub 2010 Feb 5.

11.

14-3-3ζ up-regulates hypoxia-inducible factor-1α in hepatocellular carcinoma via activation of PI3K/Akt/NF-кB signal transduction pathway.

Tang Y, Lv P, Sun Z, Han L, Luo B, Zhou W.

Int J Clin Exp Pathol. 2015 Dec 1;8(12):15845-53. eCollection 2015.

12.

Mesenchymal Stem Cell Migration and Proliferation Are Mediated by Hypoxia-Inducible Factor-1α Upstream of Notch and SUMO Pathways.

Ciria M, García NA, Ontoria-Oviedo I, González-King H, Carrero R, De La Pompa JL, Montero JA, Sepúlveda P.

Stem Cells Dev. 2017 Jul 1;26(13):973-985. doi: 10.1089/scd.2016.0331. Epub 2017 May 18.

13.

Ursolic acid inhibits proliferation and reverses drug resistance of ovarian cancer stem cells by downregulating ABCG2 through suppressing the expression of hypoxia-inducible factor-1α in vitro.

Wang WJ, Sui H, Qi C, Li Q, Zhang J, Wu SF, Mei MZ, Lu YY, Wan YT, Chang H, Guo PT.

Oncol Rep. 2016 Jul;36(1):428-40. doi: 10.3892/or.2016.4813. Epub 2016 May 18.

PMID:
27221674
14.

Rapid non-genomic signalling by 17β-oestradiol through c-Src involves mTOR-dependent expression of HIF-1α in breast cancer cells.

Sudhagar S, Sathya S, Lakshmi BS.

Br J Cancer. 2011 Sep 27;105(7):953-60. doi: 10.1038/bjc.2011.349. Epub 2011 Sep 6.

15.

Interaction of hypoxia-inducible factor-1α and Notch signaling regulates medulloblastoma precursor proliferation and fate.

Pistollato F, Rampazzo E, Persano L, Abbadi S, Frasson C, Denaro L, D'Avella D, Panchision DM, Della Puppa A, Scienza R, Basso G.

Stem Cells. 2010 Nov;28(11):1918-29. doi: 10.1002/stem.518.

16.

Inflammatory interferon activates HIF-1α-mediated epithelial-to-mesenchymal transition via PI3K/AKT/mTOR pathway.

Yeh YH, Hsiao HF, Yeh YC, Chen TW, Li TK.

J Exp Clin Cancer Res. 2018 Mar 27;37(1):70. doi: 10.1186/s13046-018-0730-6.

17.

Endothelin-1 inhibits prolyl hydroxylase domain 2 to activate hypoxia-inducible factor-1alpha in melanoma cells.

Spinella F, Rosanò L, Del Duca M, Di Castro V, Nicotra MR, Natali PG, Bagnato A.

PLoS One. 2010 Jun 21;5(6):e11241. doi: 10.1371/journal.pone.0011241.

18.

YC-1 inhibits HIF-1 expression in prostate cancer cells: contribution of Akt/NF-kappaB signaling to HIF-1alpha accumulation during hypoxia.

Sun HL, Liu YN, Huang YT, Pan SL, Huang DY, Guh JH, Lee FY, Kuo SC, Teng CM.

Oncogene. 2007 Jun 7;26(27):3941-51. Epub 2007 Jan 8.

PMID:
17213816
19.

Celecoxib Down-Regulates the Hypoxia-Induced Expression of HIF-1α and VEGF Through the PI3K/AKT Pathway in Retinal Pigment Epithelial Cells.

Sun YZ, Cai N, Liu NN.

Cell Physiol Biochem. 2017;44(4):1640-1650. doi: 10.1159/000485764. Epub 2017 Dec 6.

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