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Long-Lasting Transcriptional Changes in Circulating Monocytes of Acute Q Fever Patients.

Raijmakers RP, Stenos J, Keijmel SP, Ter Horst R, Novakovic B, Nguyen C, Van Der Meer JW, Netea MG, Bleeker-Rovers CP, Joosten LA, Graves SR.

Open Forum Infect Dis. 2019 Jul 1;6(7). pii: ofz296. doi: 10.1093/ofid/ofz296.


Cytokine profiles in patients with Q fever fatigue syndrome.

Raijmakers RPH, Koeken VACM, Jansen AFM, Keijmel SP, Roerink ME, Joosten LAB, Netea MG, van der Meer JWM, Bleeker-Rovers CP.

J Infect. 2019 May;78(5):349-357. doi: 10.1016/j.jinf.2019.01.006. Epub 2019 Jan 23.


A possible link between recurrent upper respiratory tract infections and lower cytokine production in patients with Q fever fatigue syndrome.

Raijmakers RPH, Jansen AFM, Keijmel SP, van der Meer JWM, Joosten LAB, Netea MG, Bleeker-Rovers CP.

Eur J Immunol. 2019 Jul;49(7):1015-1022. doi: 10.1002/eji.201848012. Epub 2019 May 9.


A possible role for mitochondrial-derived peptides humanin and MOTS-c in patients with Q fever fatigue syndrome and chronic fatigue syndrome.

Raijmakers RPH, Jansen AFM, Keijmel SP, Ter Horst R, Roerink ME, Novakovic B, Joosten LAB, van der Meer JWM, Netea MG, Bleeker-Rovers CP.

J Transl Med. 2019 May 14;17(1):157. doi: 10.1186/s12967-019-1906-3.


Cytokine dysregulation in the post-Q-fever fatigue syndrome.

Penttila IA, Harris RJ, Storm P, Haynes D, Worswick DA, Marmion BP.

QJM. 1998 Aug;91(8):549-60.


Altered interferon-γ response in patients with Q-fever fatigue syndrome.

Keijmel SP, Raijmakers RP, Bleeker-Rovers CP, van der Meer JW, Netea MG, Schoffelen T, van Deuren M.

J Infect. 2016 Apr;72(4):478-85. doi: 10.1016/j.jinf.2016.01.004. Epub 2016 Jan 25.


Interferon-γ and CXCL10 responses related to complaints in patients with Q fever fatigue syndrome.

Raijmakers RPH, Jansen AFM, Keijmel SP, Schoffelen T, Scholzen A, van der Meer JWM, Joosten LAB, Netea MG, van Deuren M, Bleeker-Rovers CP.

Eur J Clin Microbiol Infect Dis. 2018 Jul;37(7):1385-1391. doi: 10.1007/s10096-018-3265-z. Epub 2018 May 26.


High-fat meals induce systemic cytokine release without evidence of endotoxemia-mediated cytokine production from circulating monocytes or myeloid dendritic cells.

Fogarty CL, Nieminen JK, Peräneva L, Lassenius MI, Ahola AJ, Taskinen MR, Jauhiainen M, Kirveskari J, Pussinen P, Hörkkö S, Mäkinen VP, Gordin D, Forsblom C, Groop PH, Vaarala O, Lehto M.

Acta Diabetol. 2015 Apr;52(2):315-22. doi: 10.1007/s00592-014-0641-8. Epub 2014 Sep 3.


Plasma cytokines, cytokine antagonists, and disease progression in African women infected with HIV-1.

Thea DM, Porat R, Nagimbi K, Baangi M, St Louis ME, Kaplan G, Dinarello CA, Keusch GT.

Ann Intern Med. 1996 Apr 15;124(8):757-62.


Circulating cytokine balance and activation markers of leucocytes in Q fever.

Capo C, Amirayan N, Ghigo E, Raoult D, Mege J.

Clin Exp Immunol. 1999 Jan;115(1):120-3.


Effectiveness of Long-term Doxycycline Treatment and Cognitive-Behavioral Therapy on Fatigue Severity in Patients with Q Fever Fatigue Syndrome (Qure Study): A Randomized Controlled Trial.

Keijmel SP, Delsing CE, Bleijenberg G, van der Meer JWM, Donders RT, Leclercq M, Kampschreur LM, van den Berg M, Sprong T, Nabuurs-Franssen MH, Knoop H, Bleeker-Rovers CP.

Clin Infect Dis. 2017 Apr 15;64(8):998-1005. doi: 10.1093/cid/cix013.


Interleukin-1 receptor antagonist expression is inversely associated with outcomes of hepatitis B-related acute-on-chronic liver failure.

Lai J, Liu Y, Pan C, Lin C, Sun F, Huang Z, Lin Y, Zhou R, Lin Y, Zhou Y.

Exp Ther Med. 2017 Jun;13(6):2867-2875. doi: 10.3892/etm.2017.4361. Epub 2017 Apr 19.


[Persistent fatigue following Q fever].

Keijmel SP, Morroy G, Delsing CE, Bleijenberg G, Bleeker-Rovers CP, Timen A.

Ned Tijdschr Geneeskd. 2012;156(48):A5258. Review. Dutch.


Evaluation of IL-1β, IL-1ra, and IL-10 levels and outcome of periodontal therapy in chronic periodontitis with familial Mediterranean fever.

Bostanci V, Toker H, Senel S, Poyraz O, Akpinar A, Görgün EP, Bakar O.

Clin Oral Investig. 2017 Jan;21(1):469-475. doi: 10.1007/s00784-016-1816-1. Epub 2016 Apr 11.


Influence of the IL-1Ra gene polymorphism on in vivo synthesis of IL-1Ra and IL-1beta after live yellow fever vaccination.

Hacker UT, Erhardt S, Tschöp K, Jelinek T, Endres S.

Clin Exp Immunol. 2001 Sep;125(3):465-9.


Circulating interleukin-1 receptor antagonist concentrations are increased in adult patients with thermal injury.

Mandrup-Poulsen T, Wogensen LD, Jensen M, Svensson P, Nilsson P, Emdal T, Mølvig J, Dinarello CA, Nerup J.

Crit Care Med. 1995 Jan;23(1):26-33.


Profile of circulating levels of IL-1Ra, CXCL10/IP-10, CCL4/MIP-1β and CCL2/MCP-1 in dengue fever and parvovirosis.

de-Oliveira-Pinto LM, Gandini M, Freitas LP, Siqueira MM, Marinho CF, Setúbal S, Kubelka CF, Cruz OG, Oliveira SA.

Mem Inst Oswaldo Cruz. 2012 Feb;107(1):48-56.


The Qure study: Q fever fatigue syndrome--response to treatment; a randomized placebo-controlled trial.

Keijmel SP, Delsing CE, Sprong T, Bleijenberg G, van der Meer JW, Knoop H, Bleeker-Rovers CP.

BMC Infect Dis. 2013 Mar 27;13:157. doi: 10.1186/1471-2334-13-157.


Fatigue following Acute Q-Fever: A Systematic Literature Review.

Morroy G, Keijmel SP, Delsing CE, Bleijenberg G, Langendam M, Timen A, Bleeker-Rovers CP.

PLoS One. 2016 May 25;11(5):e0155884. doi: 10.1371/journal.pone.0155884. eCollection 2016. Review.

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