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Items: 1 to 20 of 96

1.

Constitutive Activation of the B Cell Receptor Underlies Dysfunctional Signaling in Chronic Lymphocytic Leukemia.

Ziegler CGK, Kim J, Piersanti K, Oyler-Yaniv A, Argyropoulos KV, van den Brink MRM, Palomba ML, Altan-Bonnet N, Altan-Bonnet G.

Cell Rep. 2019 Jul 23;28(4):923-937.e3. doi: 10.1016/j.celrep.2019.06.069.

2.

B Cell Anergy Modulated by TLR1/2 and the miR-17∼92 Cluster Underlies the Indolent Clinical Course of Chronic Lymphocytic Leukemia Stereotyped Subset #4.

Ntoufa S, Papakonstantinou N, Apollonio B, Gounari M, Galigalidou C, Fonte E, Anagnostopoulos A, Belessi C, Muzio M, Ghia P, Stamatopoulos K.

J Immunol. 2016 May 15;196(10):4410-7. doi: 10.4049/jimmunol.1502297. Epub 2016 Apr 8.

3.

Aberrant B cell receptor signaling from B29 (Igbeta, CD79b) gene mutations of chronic lymphocytic leukemia B cells.

Gordon MS, Kato RM, Lansigan F, Thompson AA, Wall R, Rawlings DJ.

Proc Natl Acad Sci U S A. 2000 May 9;97(10):5504-9.

4.

B-cell antigen receptor signaling enhances chronic lymphocytic leukemia cell migration and survival: specific targeting with a novel spleen tyrosine kinase inhibitor, R406.

Quiroga MP, Balakrishnan K, Kurtova AV, Sivina M, Keating MJ, Wierda WG, Gandhi V, Burger JA.

Blood. 2009 Jul 30;114(5):1029-37. doi: 10.1182/blood-2009-03-212837. Epub 2009 Jun 2.

5.

Comparison of the mRNA expression profile of B-cell receptor components in normal CD5-high B-lymphocytes and chronic lymphocytic leukemia: a key role of ZAP70.

Gladkikh AA, Potashnikova DM, Tatarskiy V Jr, Yastrebova M, Khamidullina A, Barteneva N, Vorobjev I.

Cancer Med. 2017 Dec;6(12):2984-2997. doi: 10.1002/cam4.1257. Epub 2017 Nov 10.

6.

Proteomic analysis of B-cell receptor signaling in chronic lymphocytic leukaemia reveals a possible role for kininogen.

Kashuba E, Eagle GL, Bailey J, Evans P, Welham KJ, Allsup D, Cawkwell L.

J Proteomics. 2013 Oct 8;91:478-85. doi: 10.1016/j.jprot.2013.08.002. Epub 2013 Aug 11.

PMID:
23938224
7.

Sustained signaling through the B-cell receptor induces Mcl-1 and promotes survival of chronic lymphocytic leukemia B cells.

Petlickovski A, Laurenti L, Li X, Marietti S, Chiusolo P, Sica S, Leone G, Efremov DG.

Blood. 2005 Jun 15;105(12):4820-7. Epub 2005 Feb 22.

PMID:
15728130
8.

Multidimensional single-cell analysis of BCR signaling reveals proximal activation defect as a hallmark of chronic lymphocytic leukemia B cells.

Palomba ML, Piersanti K, Ziegler CG, Decker H, Cotari JW, Bantilan K, Rijo I, Gardner JR, Heaney M, Bemis D, Balderas R, Malek SN, Seymour E, Zelenetz AD, van den Brink MR, Altan-Bonnet G.

PLoS One. 2014 Jan 29;9(1):e79987. doi: 10.1371/journal.pone.0079987. eCollection 2014.

9.

Calcium signaling and cell fate: how can Ca2+ signals contribute to wrong decisions for Chronic Lymphocytic Leukemic B lymphocyte outcome?

Debant M, Hemon P, Brigaudeau C, Renaudineau Y, Mignen O.

Int J Dev Biol. 2015;59(7-9):379-89. doi: 10.1387/ijdb.150204om. Review.

10.

Stereotyped B-cell receptors in chronic lymphocytic leukemia.

Agathangelidis A, Vardi A, Baliakas P, Stamatopoulos K.

Leuk Lymphoma. 2014 Oct;55(10):2252-61. doi: 10.3109/10428194.2013.879715. Epub 2014 Mar 17. Review.

PMID:
24397617
11.

Regulation of MAPK signaling and implications in chronic lymphocytic leukemia.

Shukla A, Shukla V, Joshi SS.

Leuk Lymphoma. 2018 Jul;59(7):1565-1573. doi: 10.1080/10428194.2017.1370548. Epub 2017 Sep 7. Review.

PMID:
28882083
12.

CXCR4- and BCR-triggered integrin activation in B-cell chronic lymphocytic leukemia cells depends on JAK2-activated Bruton's tyrosine kinase.

Montresor A, Toffali L, Rigo A, Ferrarini I, Vinante F, Laudanna C.

Oncotarget. 2018 Oct 12;9(80):35123-35140. doi: 10.18632/oncotarget.26212. eCollection 2018 Oct 12.

13.

The lymph node microenvironment promotes B-cell receptor signaling, NF-kappaB activation, and tumor proliferation in chronic lymphocytic leukemia.

Herishanu Y, Pérez-Galán P, Liu D, Biancotto A, Pittaluga S, Vire B, Gibellini F, Njuguna N, Lee E, Stennett L, Raghavachari N, Liu P, McCoy JP, Raffeld M, Stetler-Stevenson M, Yuan C, Sherry R, Arthur DC, Maric I, White T, Marti GE, Munson P, Wilson WH, Wiestner A.

Blood. 2011 Jan 13;117(2):563-74. doi: 10.1182/blood-2010-05-284984. Epub 2010 Oct 12.

14.

B cell receptor signaling in chronic lymphocytic leukemia.

Burger JA, Chiorazzi N.

Trends Immunol. 2013 Dec;34(12):592-601. doi: 10.1016/j.it.2013.07.002. Epub 2013 Aug 5. Review.

15.

B-cell receptor signaling in chronic lymphocytic leukemia.

Stevenson FK, Krysov S, Davies AJ, Steele AJ, Packham G.

Blood. 2011 Oct 20;118(16):4313-20. doi: 10.1182/blood-2011-06-338855. Epub 2011 Aug 3.

PMID:
21816833
16.

Signaling pathways activated by the B-cell receptor in chronic lymphocytic leukemia.

Scupoli MT, Pizzolo G.

Expert Rev Hematol. 2012 Jun;5(3):341-8. doi: 10.1586/ehm.12.21. Review.

PMID:
22780213
17.

Antigen receptor nonresponsiveness in chronic lymphocytic leukemia B cells.

Lankester AC, van Schijndel GM, van der Schoot CE, van Oers MH, van Noesel CJ, van Lier RA.

Blood. 1995 Aug 1;86(3):1090-7.

PMID:
7620163
18.

Integration of innate into adaptive immune responses in ZAP-70-positive chronic lymphocytic leukemia.

Wagner M, Oelsner M, Moore A, Götte F, Kuhn PH, Haferlach T, Fiegl M, Bogner C, Baxter EJ, Peschel C, Follows GA, Ringshausen I.

Blood. 2016 Jan 28;127(4):436-48. doi: 10.1182/blood-2015-05-646935. Epub 2015 Oct 27.

PMID:
26508782
19.

BCR signaling in chronic lymphocytic leukemia and related inhibitors currently in clinical studies.

Robak T, Robak P.

Int Rev Immunol. 2013 Aug;32(4):358-76. doi: 10.3109/08830185.2013.786711. Epub 2013 Apr 25. Review.

PMID:
23617253
20.

TLR-9 and IL-15 Synergy Promotes the In Vitro Clonal Expansion of Chronic Lymphocytic Leukemia B Cells.

Mongini PK, Gupta R, Boyle E, Nieto J, Lee H, Stein J, Bandovic J, Stankovic T, Barrientos J, Kolitz JE, Allen SL, Rai K, Chu CC, Chiorazzi N.

J Immunol. 2015 Aug 1;195(3):901-23. doi: 10.4049/jimmunol.1403189. Epub 2015 Jul 1.

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