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Items: 1 to 20 of 101


LncRNA HAND2-AS1 promotes liver cancer stem cell self-renewal via BMP signaling.

Wang Y, Zhu P, Luo J, Wang J, Liu Z, Wu W, Du Y, Ye B, Wang D, He L, Ren W, Wang J, Sun X, Chen R, Tian Y, Fan Z.

EMBO J. 2019 Sep 2;38(17):e101110. doi: 10.15252/embj.2018101110. Epub 2019 Jul 23.


The long noncoding RNA lncTCF7 promotes self-renewal of human liver cancer stem cells through activation of Wnt signaling.

Wang Y, He L, Du Y, Zhu P, Huang G, Luo J, Yan X, Ye B, Li C, Xia P, Zhang G, Tian Y, Chen R, Fan Z.

Cell Stem Cell. 2015 Apr 2;16(4):413-25. doi: 10.1016/j.stem.2015.03.003.


Long noncoding RNA lncHand2 promotes liver repopulation via c-Met signaling.

Wang Y, Zhu P, Wang J, Zhu X, Luo J, Meng S, Wu J, Ye B, He L, Du Y, He L, Chen R, Tian Y, Fan Z.

J Hepatol. 2018 Oct;69(4):861-872. doi: 10.1016/j.jhep.2018.03.029. Epub 2018 Apr 11.


The long non-coding RNA LncHDAC2 drives the self-renewal of liver cancer stem cells via activation of Hedgehog signaling.

Wu J, Zhu P, Lu T, Du Y, Wang Y, He L, Ye B, Liu B, Yang L, Wang J, Gu Y, Lan J, Hao Y, He L, Fan Z.

J Hepatol. 2019 May;70(5):918-929. doi: 10.1016/j.jhep.2018.12.015. Epub 2018 Dec 22.


Long noncoding RNA HAND2-AS1 inhibits cancer cell proliferation, migration, and invasion in esophagus squamous cell carcinoma by regulating microRNA-21.

Yan Y, Li S, Wang S, Rubegni P, Tognetti L, Zhang J, Yan L.

J Cell Biochem. 2019 Jun;120(6):9564-9571. doi: 10.1002/jcb.28233. Epub 2018 Dec 5.


LncRNA HAND2-AS1 overexpression inhibits cancer cell proliferation in melanoma by downregulating ROCK1.

Liu P, Du R, Yu X.

Oncol Lett. 2019 Aug;18(2):1005-1010. doi: 10.3892/ol.2019.10402. Epub 2019 May 27.


LncRNA HAND2-AS1 inhibits non-small cell lung cancer migration, invasion and maintains cell stemness through the interactions with TGF-β1.

Miao F, Chen J, Shi M, Song Y, Chen Z, Pang L.

Biosci Rep. 2019 Jan 11;39(1). pii: BSR20181525. doi: 10.1042/BSR20181525. Print 2019 Jan 31.


Long non-coding RNA HAND2-AS1 inhibits invasion and metastasis in endometrioid endometrial carcinoma through inactivating neuromedin U.

Yang X, Wang CC, Lee WYW, Trovik J, Chung TKH, Kwong J.

Cancer Lett. 2018 Jan 28;413:23-34. doi: 10.1016/j.canlet.2017.10.028. Epub 2017 Oct 26.


Energy stress-induced lncRNA HAND2-AS1 represses HIF1α-mediated energy metabolism and inhibits osteosarcoma progression.

Kang Y, Zhu X, Xu Y, Tang Q, Huang Z, Zhao Z, Lu J, Song G, Xu H, Deng C, Wang J.

Am J Cancer Res. 2018 Mar 1;8(3):526-537. eCollection 2018.


LncRNA HAND2-AS1 exerts anti-oncogenic effects on ovarian cancer via restoration of BCL2L11 as a sponge of microRNA-340-5p.

Chen J, Lin Y, Jia Y, Xu T, Wu F, Jin Y.

J Cell Physiol. 2019 Dec;234(12):23421-23436. doi: 10.1002/jcp.28911. Epub 2019 Jun 21.


Down-regulated lncRNA DLX6-AS1 inhibits tumorigenesis through STAT3 signaling pathway by suppressing CADM1 promoter methylation in liver cancer stem cells.

Wu DM, Zheng ZH, Zhang YB, Fan SH, Zhang ZF, Wang YJ, Zheng YL, Lu J.

J Exp Clin Cancer Res. 2019 Jun 6;38(1):237. doi: 10.1186/s13046-019-1239-3.


lncRNA HAND2-AS1 inhibits cancer cell proliferation, migration and invasion by downregulating ROCK1 in HPV-positive and negative cervical squamous cell carcinoma.

Jin L, Ji J, Shi L, Jin S, Pei L.

Exp Ther Med. 2019 Oct;18(4):2512-2518. doi: 10.3892/etm.2019.7830. Epub 2019 Jul 30.


Long non-coding RNA HAND2-AS1 targets glucose metabolism and inhibits cancer cell proliferation in osteosarcoma.

Chen S, Xu X, Lu S, Hu B.

Oncol Lett. 2019 Aug;18(2):1323-1329. doi: 10.3892/ol.2019.10445. Epub 2019 Jun 7.


LncRNA HAND2-AS1 sponging miR-1275 suppresses colorectal cancer progression by upregulating KLF14.

Zhou J, Lin J, Zhang H, Zhu F, Xie R.

Biochem Biophys Res Commun. 2018 Sep 10;503(3):1848-1853. doi: 10.1016/j.bbrc.2018.07.125. Epub 2018 Aug 1.


Long noncoding RNA glypican 3 (GPC3) antisense transcript 1 promotes hepatocellular carcinoma progression via epigenetically activating GPC3.

Zhu XT, Yuan JH, Zhu TT, Li YY, Cheng XY.

FEBS J. 2016 Oct;283(20):3739-3754. doi: 10.1111/febs.13839. Epub 2016 Sep 21.


A novel lncRNA MCM3AP-AS1 promotes the growth of hepatocellular carcinoma by targeting miR-194-5p/FOXA1 axis.

Wang Y, Yang L, Chen T, Liu X, Guo Y, Zhu Q, Tong X, Yang W, Xu Q, Huang D, Tu K.

Mol Cancer. 2019 Feb 19;18(1):28. doi: 10.1186/s12943-019-0957-7.


The long noncoding RNA GAS8-AS1 suppresses hepatocarcinogenesis by epigenetically activating the tumor suppressor GAS8.

Pan W, Zhang N, Liu W, Liu J, Zhou L, Liu Y, Yang M.

J Biol Chem. 2018 Nov 2;293(44):17154-17165. doi: 10.1074/jbc.RA118.003055. Epub 2018 Sep 18.


LncRNA KTN1-AS1 promotes tumor growth of hepatocellular carcinoma by targeting miR-23c/ERBB2IP axis.

Zhang L, Wang L, Wang Y, Chen T, Liu R, Yang W, Liu Q, Tu K.

Biomed Pharmacother. 2019 Jan;109:1140-1147. doi: 10.1016/j.biopha.2018.10.105. Epub 2018 Nov 6.


Long Noncoding RNA lncCAMTA1 Promotes Proliferation and Cancer Stem Cell-Like Properties of Liver Cancer by Inhibiting CAMTA1.

Ding LJ, Li Y, Wang SD, Wang XS, Fang F, Wang WY, Lv P, Zhao DH, Wei F, Qi L.

Int J Mol Sci. 2016 Sep 23;17(10). pii: E1617. doi: 10.3390/ijms17101617.


The HNF1α-regulated lncRNA HNF1A-AS1 reverses the malignancy of hepatocellular carcinoma by enhancing the phosphatase activity of SHP-1.

Ding CH, Yin C, Chen SJ, Wen LZ, Ding K, Lei SJ, Liu JP, Wang J, Chen KX, Jiang HL, Zhang X, Luo C, Xie WF.

Mol Cancer. 2018 Feb 21;17(1):63. doi: 10.1186/s12943-018-0813-1.

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