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Items: 1 to 20 of 103

1.

Insulin Resistance Exacerbates Genetic Predisposition to Nonalcoholic Fatty Liver Disease in Individuals Without Diabetes.

Barata L, Feitosa MF, Bielak LF, Halligan B, Baldridge AS, Guo X, Yerges-Armstrong LM, Smith AV, Yao J, Palmer ND, VanWagner LB, Carr JJ, Chen YI, Allison M, Budoff MJ, Handelman SK, Kardia SLR, Mosley TH Jr, Ryan K, Harris TB, Launer LJ, Gudnason V, Rotter JI, Fornage M, Rasmussen-Torvik LJ, Borecki IB, O'Connell JR, Peyser PA, Speliotes EK, Province MA.

Hepatol Commun. 2019 Apr 18;3(7):894-907. doi: 10.1002/hep4.1353. eCollection 2019 Jul.

2.

Association between variants in or near PNPLA3, GCKR, and PPP1R3B with ultrasound-defined steatosis based on data from the third National Health and Nutrition Examination Survey.

Hernaez R, McLean J, Lazo M, Brancati FL, Hirschhorn JN, Borecki IB, Harris TB; Genetics of Obesity-Related Liver Disease (GOLD) Consortium, Nguyen T, Kamel IR, Bonekamp S, Eberhardt MS, Clark JM, Kao WH, Speliotes EK.

Clin Gastroenterol Hepatol. 2013 Sep;11(9):1183-1190.e2. doi: 10.1016/j.cgh.2013.02.011. Epub 2013 Feb 13.

3.

Genetic variants in GCKR and PNPLA3 confer susceptibility to nonalcoholic fatty liver disease in obese individuals.

Lin YC, Chang PF, Chang MH, Ni YH.

Am J Clin Nutr. 2014 Apr;99(4):869-74. doi: 10.3945/ajcn.113.079749. Epub 2014 Jan 29.

PMID:
24477042
4.

Characterization of European ancestry nonalcoholic fatty liver disease-associated variants in individuals of African and Hispanic descent.

Palmer ND, Musani SK, Yerges-Armstrong LM, Feitosa MF, Bielak LF, Hernaez R, Kahali B, Carr JJ, Harris TB, Jhun MA, Kardia SL, Langefeld CD, Mosley TH Jr, Norris JM, Smith AV, Taylor HA, Wagenknecht LE, Liu J, Borecki IB, Peyser PA, Speliotes EK.

Hepatology. 2013 Sep;58(3):966-75. doi: 10.1002/hep.26440. Epub 2013 Jul 16.

5.

Genetic determinants of hepatic steatosis and serum cytokeratin-18 fragment levels in Taiwanese children.

Lin YC, Chang PF, Chang MH, Ni YH.

Liver Int. 2018 Jul;38(7):1300-1307. doi: 10.1111/liv.13689. Epub 2018 Jan 24.

PMID:
29314568
6.

Patatin-like phospholipase domain containing 3 variants differentially impact metabolic traits in individuals at high risk for cardiovascular events.

Rüschenbaum S, Schwarzkopf K, Friedrich-Rust M, Seeger F, Schoelzel F, Martinez Y, Zeuzem S, Bojunga J, Lange CM.

Hepatol Commun. 2018 Jun 6;2(7):798-806. doi: 10.1002/hep4.1183. eCollection 2018 Jul.

7.

Patatin-like phospholipase domain-containing protein 3 rs738409-G in recipients of liver transplants is a risk factor for graft steatosis.

Finkenstedt A, Auer C, Glodny B, Posch U, Steitzer H, Lanzer G, Pratschke J, Biebl M, Steurer M, Graziadei I, Vogel W, Zoller H.

Clin Gastroenterol Hepatol. 2013 Dec;11(12):1667-72. doi: 10.1016/j.cgh.2013.06.025. Epub 2013 Jul 18.

PMID:
23872669
8.

PNPLA3 p.I148M variant is associated with greater reduction of liver fat content after bariatric surgery.

Krawczyk M, Jiménez-Agüero R, Alustiza JM, Emparanza JI, Perugorria MJ, Bujanda L, Lammert F, Banales JM.

Surg Obes Relat Dis. 2016 Dec;12(10):1838-1846. doi: 10.1016/j.soard.2016.06.004. Epub 2016 Jul 1.

PMID:
27576208
9.

PNPLA3 gene-by-visceral adipose tissue volume interaction and the pathogenesis of fatty liver disease: the NHLBI family heart study.

Graff M, North KE, Franceschini N, Reiner AP, Feitosa M, Carr JJ, Gordon-Larsen P, Wojczynski MK, Borecki IB.

Int J Obes (Lond). 2013 Mar;37(3):432-8. doi: 10.1038/ijo.2012.65. Epub 2012 May 1.

10.

Liver and Cardiovascular Damage in Patients With Lean Nonalcoholic Fatty Liver Disease, and Association With Visceral Obesity.

Fracanzani AL, Petta S, Lombardi R, Pisano G, Russello M, Consonni D, Di Marco V, Cammà C, Mensi L, Dongiovanni P, Valenti L, Craxì A, Fargion S.

Clin Gastroenterol Hepatol. 2017 Oct;15(10):1604-1611.e1. doi: 10.1016/j.cgh.2017.04.045. Epub 2017 May 26.

PMID:
28554682
11.

A common variant in the patatin-like phospholipase 3 gene (PNPLA3) is associated with fatty liver disease in obese children and adolescents.

Santoro N, Kursawe R, D'Adamo E, Dykas DJ, Zhang CK, Bale AE, Calí AM, Narayan D, Shaw MM, Pierpont B, Savoye M, Lartaud D, Eldrich S, Cushman SW, Zhao H, Shulman GI, Caprio S.

Hepatology. 2010 Oct;52(4):1281-90. doi: 10.1002/hep.23832.

12.

APOC3 rs2070666 Is Associated with the Hepatic Steatosis Independently of PNPLA3 rs738409 in Chinese Han Patients with Nonalcoholic Fatty Liver Diseases.

Zhang RN, Zheng RD, Mi YQ, Zhou D, Shen F, Chen GY, Zhu CY, Pan Q, Fan JG.

Dig Dis Sci. 2016 Aug;61(8):2284-93. doi: 10.1007/s10620-016-4120-7. Epub 2016 Apr 8.

PMID:
27059980
13.

Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease.

Hotta K, Yoneda M, Hyogo H, Ochi H, Mizusawa S, Ueno T, Chayama K, Nakajima A, Nakao K, Sekine A.

BMC Med Genet. 2010 Dec 22;11:172. doi: 10.1186/1471-2350-11-172.

14.

No correlation between PNPLA3 rs738409 genotype and fatty liver and hepatic cirrhosis in Japanese patients with HCV.

Nakamura M, Kanda T, Nakamoto S, Miyamura T, Jiang X, Wu S, Yokosuka O.

PLoS One. 2013 Dec 11;8(12):e81312. doi: 10.1371/journal.pone.0081312. eCollection 2013.

15.

I148M variant of PNPLA3 increases the susceptibility to non-alcoholic fatty liver disease caused by obesity and metabolic disorders.

Xia MF, Ling Y, Bian H, Lin HD, Yan HM, Chang XX, Li XM, Ma H, Wang D, Zhang LS, Wang SS, Wu BJ, He WY, Zhao NQ, Gao X.

Aliment Pharmacol Ther. 2016 Mar;43(5):631-42. doi: 10.1111/apt.13521. Epub 2016 Jan 13.

16.

The PNPLA3 rs738409 G-allele associates with reduced fasting serum triglyceride and serum cholesterol in Danes with impaired glucose regulation.

Krarup NT, Grarup N, Banasik K, Friedrichsen M, Færch K, Sandholt CH, Jørgensen T, Poulsen P, Witte DR, Vaag A, Sørensen T, Pedersen O, Hansen T.

PLoS One. 2012;7(7):e40376. doi: 10.1371/journal.pone.0040376. Epub 2012 Jul 5.

17.

I148M variant in PNPLA3 reduces central adiposity and metabolic disease risks while increasing nonalcoholic fatty liver disease.

Park JH, Cho B, Kwon H, Prilutsky D, Yun JM, Choi HC, Hwang KB, Lee IH, Kim JI, Kong SW.

Liver Int. 2015 Dec;35(12):2537-46. doi: 10.1111/liv.12909. Epub 2015 Jul 23.

PMID:
26148225
18.

Interactions of a PPARGC1A Variant and a PNPLA3 Variant Affect Nonalcoholic Steatohepatitis in Severely Obese Taiwanese Patients.

Tai CM, Huang CK, Tu HP, Hwang JC, Yeh ML, Huang CF, Huang JF, Dai CY, Chuang WL, Yu ML.

Medicine (Baltimore). 2016 Mar;95(12):e3120. doi: 10.1097/MD.0000000000003120.

19.

I148M patatin-like phospholipase domain-containing 3 gene variant and severity of pediatric nonalcoholic fatty liver disease.

Valenti L, Alisi A, Galmozzi E, Bartuli A, Del Menico B, Alterio A, Dongiovanni P, Fargion S, Nobili V.

Hepatology. 2010 Oct;52(4):1274-80. doi: 10.1002/hep.23823.

PMID:
20648474
20.

Additive Effects of the Risk Alleles of PNPLA3 and TM6SF2 on Non-alcoholic Fatty Liver Disease (NAFLD) in a Chinese Population.

Wang X, Liu Z, Wang K, Wang Z, Sun X, Zhong L, Deng G, Song G, Sun B, Peng Z, Liu W.

Front Genet. 2016 Aug 2;7:140. doi: 10.3389/fgene.2016.00140. eCollection 2016.

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