Format
Sort by
Items per page

Send to

Choose Destination

Links from PubMed

Items: 1 to 20 of 96

1.

Antioxidant, Anti-inflammatory, and Neuroprotective Effects of Novel Vinyl Sulfonate Compounds as Nrf2 Activator.

Choi JW, Shin SJ, Kim HJ, Park JH, Kim HJ, Lee EH, Pae AN, Bahn YS, Park KD.

ACS Med Chem Lett. 2019 Jun 3;10(7):1061-1067. doi: 10.1021/acsmedchemlett.9b00163. eCollection 2019 Jul 11.

PMID:
31312409
2.

Discovery of vinyl sulfones as a novel class of neuroprotective agents toward Parkinson's disease therapy.

Woo SY, Kim JH, Moon MK, Han SH, Yeon SK, Choi JW, Jang BK, Song HJ, Kang YG, Kim JW, Lee J, Kim DJ, Hwang O, Park KD.

J Med Chem. 2014 Feb 27;57(4):1473-87. doi: 10.1021/jm401788m. Epub 2014 Feb 5.

PMID:
24467268
3.

Optimization of Vinyl Sulfone Derivatives as Potent Nuclear Factor Erythroid 2-Related Factor 2 (Nrf2) Activators for Parkinson's Disease Therapy.

Choi JW, Kim S, Park JH, Kim HJ, Shin SJ, Kim JW, Woo SY, Lee C, Han SM, Lee J, Pae AN, Han G, Park KD.

J Med Chem. 2019 Jan 24;62(2):811-830. doi: 10.1021/acs.jmedchem.8b01527. Epub 2018 Dec 20.

PMID:
30540174
4.

Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease.

Ahuja M, Ammal Kaidery N, Yang L, Calingasan N, Smirnova N, Gaisin A, Gaisina IN, Gazaryan I, Hushpulian DM, Kaddour-Djebbar I, Bollag WB, Morgan JC, Ratan RR, Starkov AA, Beal MF, Thomas B.

J Neurosci. 2016 Jun 8;36(23):6332-51. doi: 10.1523/JNEUROSCI.0426-16.2016.

5.

A novel compound VSC2 has anti-inflammatory and antioxidant properties in microglia and in Parkinson's disease animal model.

Lee JA, Kim JH, Woo SY, Son HJ, Han SH, Jang BK, Choi JW, Kim DJ, Park KD, Hwang O.

Br J Pharmacol. 2015 Feb;172(4):1087-100. doi: 10.1111/bph.12973. Epub 2014 Dec 15.

6.

Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease.

Kaidery NA, Banerjee R, Yang L, Smirnova NA, Hushpulian DM, Liby KT, Williams CR, Yamamoto M, Kensler TW, Ratan RR, Sporn MB, Beal MF, Gazaryan IG, Thomas B.

Antioxid Redox Signal. 2013 Jan 10;18(2):139-57. doi: 10.1089/ars.2011.4491. Epub 2012 Aug 13.

7.

A Novel Compound ITC-3 Activates the Nrf2 Signaling and Provides Neuroprotection in Parkinson's Disease Models.

Lee JA, Son HJ, Park KD, Han SH, Shin N, Kim JH, Kim HR, Kim DJ, Hwang O.

Neurotox Res. 2015 Nov;28(4):332-45. doi: 10.1007/s12640-015-9550-z. Epub 2015 Aug 2.

PMID:
26233727
8.

Nrf2-ARE signals mediated the anti-oxidative action of electroacupuncture in an MPTP mouse model of Parkinson's disease.

Lv E, Deng J, Yu Y, Wang Y, Gong X, Jia J, Wang X.

Free Radic Res. 2015;49(11):1296-307. doi: 10.3109/10715762.2015.1067696. Epub 2015 Jul 30.

PMID:
26118717
9.
10.

Multitarget intervention of Fasudil in the neuroprotection of dopaminergic neurons in MPTP-mouse model of Parkinson's disease.

Zhao YF, Zhang Q, Xi JY, Li YH, Ma CG, Xiao BG.

J Neurol Sci. 2015;353(1-2):28-37. doi: 10.1016/j.jns.2015.03.022. Epub 2015 Mar 20.

PMID:
25908255
11.

Naringenin protects against 6-OHDA-induced neurotoxicity via activation of the Nrf2/ARE signaling pathway.

Lou H, Jing X, Wei X, Shi H, Ren D, Zhang X.

Neuropharmacology. 2014 Apr;79:380-8. doi: 10.1016/j.neuropharm.2013.11.026. Epub 2013 Dec 11.

PMID:
24333330
12.

Gastrodin prevents motor deficits and oxidative stress in the MPTP mouse model of Parkinson's disease: involvement of ERK1/2-Nrf2 signaling pathway.

Wang XL, Xing GH, Hong B, Li XM, Zou Y, Zhang XJ, Dong MX.

Life Sci. 2014 Oct 2;114(2):77-85. doi: 10.1016/j.lfs.2014.08.004. Epub 2014 Aug 14.

PMID:
25132361
13.

Neuroprotective effects of tetramethylpyrazine against dopaminergic neuron injury in a rat model of Parkinson's disease induced by MPTP.

Lu C, Zhang J, Shi X, Miao S, Bi L, Zhang S, Yang Q, Zhou X, Zhang M, Xie Y, Miao Q, Wang S.

Int J Biol Sci. 2014 Mar 13;10(4):350-7. doi: 10.7150/ijbs.8366. eCollection 2014.

14.

DJ-1 regulating PI3K-Nrf2 signaling plays a significant role in bibenzyl compound 20C-mediated neuroprotection against rotenone-induced oxidative insult.

Zhang XL, Yuan YH, Shao QH, Wang ZZ, Zhu CG, Shi JG, Ma KL, Yan X, Chen NH.

Toxicol Lett. 2017 Apr 5;271:74-83. doi: 10.1016/j.toxlet.2017.02.022. Epub 2017 Feb 27.

PMID:
28245986
15.

Pinostrobin Exerts Neuroprotective Actions in Neurotoxin-Induced Parkinson's Disease Models through Nrf2 Induction.

Li C, Tang B, Feng Y, Tang F, Pui-Man Hoi M, Su Z, Ming-Yuen Lee S.

J Agric Food Chem. 2018 Aug 8;66(31):8307-8318. doi: 10.1021/acs.jafc.8b02607. Epub 2018 Jul 26.

PMID:
29961319
16.

Nrf2 activation by tauroursodeoxycholic acid in experimental models of Parkinson's disease.

Moreira S, Fonseca I, Nunes MJ, Rosa A, Lemos L, Rodrigues E, Carvalho AN, Outeiro TF, Rodrigues CMP, Gama MJ, Castro-Caldas M.

Exp Neurol. 2017 Sep;295:77-87. doi: 10.1016/j.expneurol.2017.05.009. Epub 2017 May 25.

PMID:
28552716
17.

Hydralazine Protects Nigrostriatal Dopaminergic Neurons From MPP+ and MPTP Induced Neurotoxicity: Roles of Nrf2-ARE Signaling Pathway.

Guo X, Han C, Ma K, Xia Y, Wan F, Yin S, Kou L, Sun Y, Wu J, Hu J, Huang J, Xiong N, Wang T.

Front Neurol. 2019 Mar 20;10:271. doi: 10.3389/fneur.2019.00271. eCollection 2019.

18.

Tanshinone IIA protects dopaminergic neurons against 6-hydroxydopamine-induced neurotoxicity through miR-153/NF-E2-related factor 2/antioxidant response element signaling pathway.

Zhang XS, Ha S, Wang XL, Shi YL, Duan SS, Li ZA.

Neuroscience. 2015 Sep 10;303:489-502. doi: 10.1016/j.neuroscience.2015.06.030. Epub 2015 Jun 23.

PMID:
26116522
19.

Gintonin Mitigates MPTP-Induced Loss of Nigrostriatal Dopaminergic Neurons and Accumulation of α-Synuclein via the Nrf2/HO-1 Pathway.

Jo MG, Ikram M, Jo MH, Yoo L, Chung KC, Nah SY, Hwang H, Rhim H, Kim MO.

Mol Neurobiol. 2019 Jan;56(1):39-55. doi: 10.1007/s12035-018-1020-1. Epub 2018 Apr 19.

PMID:
29675576
20.

Nrf2/ARE Signaling Pathway: Key Mediator in Oxidative Stress and Potential Therapeutic Target in ALS.

Petri S, Körner S, Kiaei M.

Neurol Res Int. 2012;2012:878030. doi: 10.1155/2012/878030. Epub 2012 Sep 20.

Supplemental Content

Support Center