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Changes in the rate of and trends in colectomy for ulcerative colitis during the era of biologics and calcineurin inhibitors based on a Japanese nationwide cohort study.

Uchino M, Ikeuchi H, Hata K, Okada S, Ishihara S, Morimoto K, Sahara R, Watanabe K, Fukushima K, Takahashi K, Kimura H, Hirata K, Mizushima T, Araki T, Kusunoki M, Nezu R, Nakao S, Itabashi M, Hirata A, Ozawa H, Ishida T, Okabayashi K, Yamamoto T, Noake T, Arakaki J, Watadani Y, Ohge H, Futatsuki R, Koganei K, Sugita A, Higashi D, Futami K.

Surg Today. 2019 Jul 15. doi: 10.1007/s00595-019-01845-2. [Epub ahead of print]


Associations between multiple immunosuppressive treatments before surgery and surgical morbidity in patients with ulcerative colitis during the era of biologics.

Uchino M, Ikeuchi H, Bando T, Chohno T, Sasaki H, Horio Y, Kuwahara R, Minagawa T, Goto Y, Ichiki K, Nakajima K, Takahashi Y, Ueda T, Takesue Y.

Int J Colorectal Dis. 2019 Apr;34(4):699-710. doi: 10.1007/s00384-019-03253-x. Epub 2019 Jan 26.


Readministration of calcineurin inhibitors for ulcerative colitis.

Hiraoka S, Kato J, Suzuki H, Yamamoto K.

Ann Pharmacother. 2012 Oct;46(10):1315-21. doi: 10.1345/aph.1R210. Epub 2012 Oct 2.


Pre-operative use of anti-TNF-α agents and the risk of post-operative complications in patients with ulcerative colitis - a nationwide cohort study.

Nørgård BM, Nielsen J, Qvist N, Gradel KO, de Muckadell OB, Kjeldsen J.

Aliment Pharmacol Ther. 2012 Jun;35(11):1301-9. doi: 10.1111/j.1365-2036.2012.05099.x. Epub 2012 Apr 16.


Short- and long-term efficacy of adalimumab salvage therapy after failure of calcineurin inhibitors in steroid-refractory ulcerative colitis.

Nishio M, Ishii Y, Hashimoto Y, Otake H, Ogashiwa T, Tsuda S, Yasuhara H, Saigusa Y, Kimura H, Maeda S, Kunisaki R.

Scand J Gastroenterol. 2018 Oct - Nov;53(10-11):1236-1244. doi: 10.1080/00365521.2018.1511825. Epub 2018 Oct 24.


Prevalence and Risk Factors for Therapy Escalation in Ulcerative Colitis in the Swiss IBD Cohort Study.

Safroneeva E, Vavricka SR, Fournier N, Straumann A, Rogler G, Schoepfer AM.

Inflamm Bowel Dis. 2015 Jun;21(6):1348-58. doi: 10.1097/MIB.0000000000000368.


Prognostic factors for colectomy in refractory ulcerative colitis treated with calcineurin inhibitors.

Bamba S, Andoh A, Imaeda H, Ban H, Kobori A, Mochizuki Y, Shioya M, Nishimura T, Inatomi O, Sasaki M, Saitoh Y, Tsujikawa T, Fujiyama Y.

Exp Ther Med. 2012 Jul;4(1):99-104. Epub 2012 Apr 11.


Impact of anti-TNF-alpha therapy on colectomy rate and indications for colectomy in ulcerative colitis: comparison of two patient cohorts from 2005 to 2007 and from 2014 to 2016.

Kolehmainen S, Lepistö A, Färkkilä M.

Scand J Gastroenterol. 2019 Jun;54(6):707-711. doi: 10.1080/00365521.2019.1620326. Epub 2019 May 28.


Review article: applying pharmacokinetics to optimise dosing of anti-TNF biologics in acute severe ulcerative colitis.

Rosen MJ, Minar P, Vinks AA.

Aliment Pharmacol Ther. 2015 Jun;41(11):1094-103. doi: 10.1111/apt.13175. Epub 2015 Mar 23. Review.


The incidence rate of colectomy for medically refractory ulcerative colitis has declined in parallel with increasing anti-TNF use: a time-trend study.

Reich KM, Chang HJ, Rezaie A, Wang H, Goodman KJ, Kaplan GG, Svenson LW, Lees G, Fedorak RN, Kroeker KI.

Aliment Pharmacol Ther. 2014 Sep;40(6):629-38. doi: 10.1111/apt.12873. Epub 2014 Jul 13.


Preoperative immunosuppression is not associated with increased postoperative complications following colectomy in children with colitis.

Schaufler C, Lerer T, Campbell B, Weiss R, Cohen J, Sayej W, Hyams J.

J Pediatr Gastroenterol Nutr. 2012 Oct;55(4):421-4.


Early predictors of colectomy and long-term maintenance of remission in ulcerative colitis patients treated using anti-tumour necrosis factor therapy.

Subramaniam K, Richardson A, Dodd J, Platten J, Shadbolt B, Pavli P.

Intern Med J. 2014 May;44(5):464-70. doi: 10.1111/imj.12397.


The Impact of Inflammatory Bowel Disease in Canada 2018: Direct Costs and Health Services Utilization.

Kuenzig ME, Benchimol EI, Lee L, Targownik LE, Singh H, Kaplan GG, Bernstein CN, Bitton A, Nguyen GC, Lee K, Cooke-Lauder J, Murthy SK.

J Can Assoc Gastroenterol. 2019 Feb;2(Suppl 1):S17-S33. doi: 10.1093/jcag/gwy055. Epub 2018 Nov 2.


Long-term prognosis of ulcerative colitis and its temporal change between 1977 and 2013: a hospital-based cohort study from Korea.

Lee HS, Park SH, Yang SK, Lee J, Soh JS, Lee S, Bae JH, Lee HJ, Yang DH, Kim KJ, Yea BD, Byeon JS, Myung SJ, Yoon YS, Yu CS, Kim JH.

J Crohns Colitis. 2015 Feb;9(2):147-55.


Generalized Pyoderma Gangrenosum Associated with Ulcerative Colitis: Successful Treatment with Infliximab and Azathioprine.

Chatzinasiou F, Polymeros D, Panagiotou M, Theodoropoulos K, Rigopoulos D.

Acta Dermatovenerol Croat. 2016 Apr;24(1):83-5.


The risk of colorectal cancer in patients with ulcerative colitis.

Nowacki TM, Brückner M, Eveslage M, Tepasse P, Pott F, Thoennissen NH, Hengst K, Ross M, Bettenworth D.

Dig Dis Sci. 2015 Feb;60(2):492-501. doi: 10.1007/s10620-014-3373-2. Epub 2014 Oct 4.


Association of Preoperative Anti-Tumor Necrosis Factor Therapy With Adverse Postoperative Outcomes in Patients Undergoing Abdominal Surgery for Ulcerative Colitis.

Kulaylat AS, Kulaylat AN, Schaefer EW, Tinsley A, Williams E, Koltun W, Hollenbeak CS, Messaris E.

JAMA Surg. 2017 Aug 16;152(8):e171538. doi: 10.1001/jamasurg.2017.1538. Epub 2017 Aug 16.


Elderly-Onset and Adult-Onset Ulcerative Colitis Are More Similar than Previously Reported in a Nationwide Cohort.

Kumar V, Shah Y, Patel D, Khan N.

Dig Dis Sci. 2017 Oct;62(10):2857-2862. doi: 10.1007/s10620-017-4734-4. Epub 2017 Sep 7.


Incidence of and impact of medications on colectomy in newly diagnosed ulcerative colitis in the era of biologics.

Williet N, Pillot C, Oussalah A, Billioud V, Chevaux JB, Bresler L, Bigard MA, Gueant JL, Peyrin-Biroulet L.

Inflamm Bowel Dis. 2012 Sep;18(9):1641-6. doi: 10.1002/ibd.21932. Epub 2011 Dec 4.


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