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Items: 1 to 20 of 100

1.

Design of balanced COX inhibitors based on anti-inflammatory and/or COX-2 inhibitory ascidian metabolites.

Ju Z, Su M, Hong J, La Kim E, Moon HR, Chung HY, Kim S, Jung JH.

Eur J Med Chem. 2019 Oct 15;180:86-98. doi: 10.1016/j.ejmech.2019.07.016. Epub 2019 Jul 6.

PMID:
31301566
2.

An Algal Metabolite-Based PPAR-γ Agonist Displayed Anti-Inflammatory Effect via Inhibition of the NF-κB Pathway.

Ju Z, Su M, Li D, Hong J, Im DS, Kim S, Kim E, Jung JH.

Mar Drugs. 2019 May 30;17(6). pii: E321. doi: 10.3390/md17060321.

3.

Potent anti-inflammatory effect of a novel furan-2,5-dione derivative, BPD, mediated by dual suppression of COX-2 activity and LPS-induced inflammatory gene expression via NF-κB inactivation.

Shin JS, Park SJ, Ryu S, Kang HB, Kim TW, Choi JH, Lee JY, Cho YW, Lee KT.

Br J Pharmacol. 2012 Mar;165(6):1926-1940. doi: 10.1111/j.1476-5381.2011.01670.x.

4.

Pinocembrin attenuates lipopolysaccharide-induced inflammatory responses in Labeo rohita macrophages via the suppression of the NF-κB signalling pathway.

Giri SS, Sen SS, Sukumaran V, Park SC.

Fish Shellfish Immunol. 2016 Sep;56:459-466. doi: 10.1016/j.fsi.2016.07.038. Epub 2016 Aug 2.

PMID:
27492123
5.

Sparassis crispa exerts anti-inflammatory activity via suppression of TLR-mediated NF-κB and MAPK signaling pathways in LPS-induced RAW264.7 macrophage cells.

Han JM, Lee EK, Gong SY, Sohng JK, Kang YJ, Jung HJ.

J Ethnopharmacol. 2019 Mar 1;231:10-18. doi: 10.1016/j.jep.2018.11.003. Epub 2018 Nov 3.

PMID:
30395976
6.

Inhibitory effects of alternaramide on inflammatory mediator expression through TLR4-MyD88-mediated inhibition of NF-кB and MAPK pathway signaling in lipopolysaccharide-stimulated RAW264.7 and BV2 cells.

Ko W, Sohn JH, Jang JH, Ahn JS, Kang DG, Lee HS, Kim JS, Kim YC, Oh H.

Chem Biol Interact. 2016 Jan 25;244:16-26. doi: 10.1016/j.cbi.2015.11.024. Epub 2015 Nov 24.

PMID:
26620692
7.

Anti-inflammatory activity of myricetin from Diospyros lotus through suppression of NF-κB and STAT1 activation and Nrf2-mediated HO-1 induction in lipopolysaccharide-stimulated RAW264.7 macrophages.

Cho BO, Yin HH, Park SH, Byun EB, Ha HY, Jang SI.

Biosci Biotechnol Biochem. 2016 Aug;80(8):1520-30. doi: 10.1080/09168451.2016.1171697. Epub 2016 Apr 12.

PMID:
27068250
8.

Zedoarondiol isolated from the rhizoma of Curcuma heyneana is involved in the inhibition of iNOS, COX-2 and pro-inflammatory cytokines via the downregulation of NF-kappaB pathway in LPS-stimulated murine macrophages.

Cho W, Nam JW, Kang HJ, Windono T, Seo EK, Lee KT.

Int Immunopharmacol. 2009 Aug;9(9):1049-57. doi: 10.1016/j.intimp.2009.04.012. Epub 2009 Apr 24.

PMID:
19398040
9.
10.

Downregulation of pro-inflammatory mediators by a water extract of Schisandra chinensis (Turcz.) Baill fruit in lipopolysaccharide-stimulated RAW 264.7 macrophage cells.

Dilshara MG, Jayasooriya RGPT, Kang CH, Lee S, Park SR, Jeong JW, Choi YH, Seo YT, Jang YP, Kim GY.

Environ Toxicol Pharmacol. 2013 Sep;36(2):256-264. doi: 10.1016/j.etap.2013.04.005. Epub 2013 Apr 19.

PMID:
23686005
11.

Arvelexin from Brassica rapa suppresses NF-κB-regulated pro-inflammatory gene expression by inhibiting activation of IκB kinase.

Shin JS, Noh YS, Lee YS, Cho YW, Baek NI, Choi MS, Jeong TS, Kang E, Chung HG, Lee KT.

Br J Pharmacol. 2011 Sep;164(1):145-58. doi: 10.1111/j.1476-5381.2011.01351.x.

12.

Suppression of inflammatory responses by handelin, a guaianolide dimer from Chrysanthemum boreale, via downregulation of NF-κB signaling and pro-inflammatory cytokine production.

Pyee Y, Chung HJ, Choi TJ, Park HJ, Hong JY, Kim JS, Kang SS, Lee SK.

J Nat Prod. 2014 Apr 25;77(4):917-24. doi: 10.1021/np4009877. Epub 2014 Apr 1.

PMID:
24689881
13.

4-methoxycinnamyl p-coumarate isolated from Etlingera pavieana rhizomes inhibits inflammatory response via suppression of NF-κB, Akt and AP-1 signaling in LPS-stimulated RAW 264.7 macrophages.

Mankhong S, Iawsipo P, Srisook E, Srisook K.

Phytomedicine. 2019 Feb 15;54:89-97. doi: 10.1016/j.phymed.2018.09.193. Epub 2018 Sep 18.

PMID:
30668386
14.

Propionibacterium acnes-induced iNOS and COX-2 protein expression via ROS-dependent NF-κB and AP-1 activation in macrophages.

Tsai HH, Lee WR, Wang PH, Cheng KT, Chen YC, Shen SC.

J Dermatol Sci. 2013 Feb;69(2):122-31. doi: 10.1016/j.jdermsci.2012.10.009. Epub 2012 Oct 24.

PMID:
23178030
15.

Phenolic rich Cocos nucifera inflorescence extract ameliorates inflammatory responses in LPS-stimulated RAW264.7 macrophages and toxin-induced murine models.

Chithra MA, Ijinu TP, Kharkwal H, Sharma RK, Pushpangadan P, George V.

Inflammopharmacology. 2019 Jul 26. doi: 10.1007/s10787-019-00620-6. [Epub ahead of print]

PMID:
31350628
16.

DXXK exerts anti-inflammatory effects by inhibiting the lipopolysaccharide-induced NF-κB/COX-2 signalling pathway and the expression of inflammatory mediators.

Yu Y, Li X, Qu L, Chen Y, Dai Y, Wang M, Zou W.

J Ethnopharmacol. 2016 Feb 3;178:199-208. doi: 10.1016/j.jep.2015.11.016. Epub 2015 Nov 10.

PMID:
26571085
17.

Anti-Inflammatory Effect of Mangostenone F in Lipopolysaccharide-Stimulated RAW264.7 Macrophages by Suppressing NF-κB and MAPK Activation.

Cho BO, Ryu HW, So Y, Lee CW, Jin CH, Yook HS, Jeong YW, Park JC, Jeong IY.

Biomol Ther (Seoul). 2014 Jul;22(4):288-94. doi: 10.4062/biomolther.2014.052.

18.
19.

Anti-inflammatory effect of Centella asiatica phytosome in a mouse model of phthalic anhydride-induced atopic dermatitis.

Ju Ho P, Jun Sung J, Ki Cheon K, Jin Tae H.

Phytomedicine. 2018 Apr 1;43:110-119. doi: 10.1016/j.phymed.2018.04.013. Epub 2018 Apr 6.

PMID:
29747743
20.

(E)-3-(3,4-Dimethoxyphenyl)-1-(5-hydroxy-2,2-dimethyl-2H-chromen-6-yl)prop-2-en-1-one ameliorates the collagen-arthritis via blocking ERK/JNK and NF-κB signaling pathway.

Li X, Peng F, Xie C, Wu W, Han X, Chen L.

Int Immunopharmacol. 2013 Dec;17(4):1125-33. doi: 10.1016/j.intimp.2013.10.001. Epub 2013 Oct 14.

PMID:
24135236

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